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ImmunocytochemistryAntibody data
- Antibody Data
- Antigen structure
- References [9]
- Comments [0]
- Validations
- Immunocytochemistry [1]
- Immunohistochemistry [2]
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- Product number
- 18727-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#18727-1-AP, RRID:AB_10637998
- Product name
- DNA2 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated DNA2 antibody (Cat. #18727-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references The germline factor DDX4 contributes to the chemoresistance of small cell lung cancer cells.
Human HELQ regulates DNA end resection at DNA double-strand breaks and stalled replication forks.
Stalled replication fork protection limits cGAS-STING and P-body-dependent innate immune signalling.
Increased Resection at DSBs in G(2)-Phase Is a Unique Phenotype Associated with DNA-PKcs Defects That Is Not Shared by Other Factors of c-NHEJ.
Increased Expression of DNA2 Was Linked to Poor Prognosis in Breast Cancer.
Characteristic Analysis of Featured Genes Associated With Stemness Indices in Colorectal Cancer.
Abro1 maintains genome stability and limits replication stress by protecting replication fork stability.
The autophagy GABARAPL1 gene is epigenetically regulated in breast cancer models.
The checkpoint clamp protein Rad9 facilitates DNA-end resection and prevents alternative non-homologous end joining.
Noyes C, Kitajima S, Li F, Suita Y, Miriyala S, Isaac S, Ahsan N, Knelson E, Vajdi A, Tani T, Thai TC, Xu D, Murai J, Tapinos N, Takahashi C, Barbie DA, Yajima M
Communications biology 2023 Jan 18;6(1):65
Communications biology 2023 Jan 18;6(1):65
Human HELQ regulates DNA end resection at DNA double-strand breaks and stalled replication forks.
Zhao Y, Hou K, Li Y, Hao S, Liu Y, Na Y, Li C, Cui J, Xu X, Wu X, Wang H
Nucleic acids research 2023 Dec 11;51(22):12207-12223
Nucleic acids research 2023 Dec 11;51(22):12207-12223
Stalled replication fork protection limits cGAS-STING and P-body-dependent innate immune signalling.
Emam A, Wu X, Xu S, Wang L, Liu S, Wang B
Nature cell biology 2022 Jul;24(7):1154-1164
Nature cell biology 2022 Jul;24(7):1154-1164
Increased Resection at DSBs in G(2)-Phase Is a Unique Phenotype Associated with DNA-PKcs Defects That Is Not Shared by Other Factors of c-NHEJ.
Xiao H, Li F, Mladenov E, Soni A, Mladenova V, Pan B, Dueva R, Stuschke M, Timmermann B, Iliakis G
Cells 2022 Jul 2;11(13)
Cells 2022 Jul 2;11(13)
Increased Expression of DNA2 Was Linked to Poor Prognosis in Breast Cancer.
Han Y, Zhang Z, Wang Z, Sun S
Disease markers 2021;2021:8860728
Disease markers 2021;2021:8860728
Characteristic Analysis of Featured Genes Associated With Stemness Indices in Colorectal Cancer.
Lu Y, Zhou X, Liu Z, Wang W, Li F, Fu W
Frontiers in molecular biosciences 2020;7:563922
Frontiers in molecular biosciences 2020;7:563922
Abro1 maintains genome stability and limits replication stress by protecting replication fork stability.
Xu S, Wu X, Wu L, Castillo A, Liu J, Atkinson E, Paul A, Su D, Schlacher K, Komatsu Y, You MJ, Wang B
Genes & development 2017 Jul 15;31(14):1469-1482
Genes & development 2017 Jul 15;31(14):1469-1482
The autophagy GABARAPL1 gene is epigenetically regulated in breast cancer models.
Hervouet E, Claude-Taupin A, Gauthier T, Perez V, Fraichard A, Adami P, Despouy G, Monnien F, Algros MP, Jouvenot M, Delage-Mourroux R, Boyer-Guittaut M
BMC cancer 2015 Oct 17;15:729
BMC cancer 2015 Oct 17;15:729
The checkpoint clamp protein Rad9 facilitates DNA-end resection and prevents alternative non-homologous end joining.
Tsai FL, Kai M
Cell cycle (Georgetown, Tex.) 2014;13(21):3460-4
Cell cycle (Georgetown, Tex.) 2014;13(21):3460-4
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The DNA2 antibody from Proteintech is a rabbit polyclonal antibody to a peptide of human DNA2. This antibody recognizes human antigen. The DNA2 antibody has been validated for the following applications: ELISA, IHC, IF analysis.
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human cervical cancer using 18727-1-AP(DNA2 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human cervical cancer using 18727-1-AP(DNA2 antibody) at dilution of 1:50 (under 40x lens)
- Sample type
- tissue
