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- Antigen structure
- References [22]
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- Product number
- 20625-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#20625-1-AP, RRID:AB_10700008
- Product name
- ZIP4 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated ZIP4 antibody (Cat. #20625-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IHC, WB,ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references A cuproptosis-related gene expression signature predicting clinical prognosis and immune responses in intrahepatic cholangiocarcinoma detected by single-cell RNA sequence analysis.
Sucrose-induced hyperglycemia dysregulates intestinal zinc metabolism and integrity: risk factors for chronic diseases.
GREM1, LRPPRC and SLC39A4 as potential biomarkers of intervertebral disc degeneration: a bioinformatics analysis based on multiple microarray and single-cell sequencing data.
Metal transporter SLC39A14/ZIP14 modulates regulation between the gut microbiome and host metabolism.
Structural Characterization of Zinc-Sucrose Complex and Its Ability to Promote Zinc Absorption in Caco-2 Monolayer Cells and Mice.
Acetyl-Coenzyme A Synthetase 2 Potentiates Macropinocytosis and Muscle Wasting Through Metabolic Reprogramming in Pancreatic Cancer.
RASSF1A independence and early galectin-1 upregulation in PIK3CA-induced hepatocarcinogenesis: new therapeutic venues.
Circular RNA ANAPC7 Inhibits Tumor Growth and Muscle Wasting via PHLPP2-AKT-TGF-β Signaling Axis in Pancreatic Cancer.
A Novel ZIP4-HDAC4-VEGFA Axis in High-Grade Serous Ovarian Cancer.
Gene expression microarray analysis of adult testicular germ cell tumor: a comparison between pure-type seminomas and seminoma components in mixed tumors.
Zinc Favors Triple-Negative Breast Cancer's Microenvironment Modulation and Cell Plasticity.
ZIP4 promotes non-small cell lung cancer metastasis by activating snail-N-cadherin signaling axis.
SLC39A4 as a Novel Prognosis Marker Promotes Tumor Progression in Esophageal Squamous Cell Carcinoma.
ZIP4 Increases Expression of Transcription Factor ZEB1 to Promote Integrin α3β1 Signaling and Inhibit Expression of the Gemcitabine Transporter ENT1 in Pancreatic Cancer Cells.
ZIP4 Is a Novel Cancer Stem Cell Marker in High-Grade Serous Ovarian Cancer.
A change in the zinc ion concentration reflects the maturation of insulin-producing cells generated from adipose-derived mesenchymal stem cells.
Inhibition of ZIP4 reverses epithelial-to-mesenchymal transition and enhances the radiosensitivity in human nasopharyngeal carcinoma cells.
Exosomal zinc transporter ZIP4 promotes cancer growth and is a novel diagnostic biomarker for pancreatic cancer.
ZIP4 Promotes Pancreatic Cancer Progression by Repressing ZO-1 and Claudin-1 through a ZEB1-Dependent Transcriptional Mechanism.
The novel ZIP4 regulation and its role in ovarian cancer.
Hepcidin Attenuates Zinc Efflux in Caco-2 Cells.
Influx mechanisms in the embryonic and adult rat choroid plexus: a transcriptome study.
Ren H, Liu C, Zhang C, Wu H, Zhang J, Wang Z, Chen L, Wang H, Shao C, Zhou L
Cancer cell international 2024 Mar 2;24(1):92
Cancer cell international 2024 Mar 2;24(1):92
Sucrose-induced hyperglycemia dysregulates intestinal zinc metabolism and integrity: risk factors for chronic diseases.
Mitchell SB, Hung YH, Thorn TL, Zou J, Baser F, Gulec S, Cheung C, Aydemir TB
Frontiers in nutrition 2023;10:1220533
Frontiers in nutrition 2023;10:1220533
GREM1, LRPPRC and SLC39A4 as potential biomarkers of intervertebral disc degeneration: a bioinformatics analysis based on multiple microarray and single-cell sequencing data.
Zhang Z, Huo J, Ji X, Wei L, Zhang J
BMC musculoskeletal disorders 2023 Sep 12;24(1):729
BMC musculoskeletal disorders 2023 Sep 12;24(1):729
Metal transporter SLC39A14/ZIP14 modulates regulation between the gut microbiome and host metabolism.
Mitchell SB, Thorn TL, Lee MT, Kim Y, Comrie JMC, Bai ZS, Johnson EL, Aydemir TB
American journal of physiology. Gastrointestinal and liver physiology 2023 Dec 1;325(6):G593-G607
American journal of physiology. Gastrointestinal and liver physiology 2023 Dec 1;325(6):G593-G607
Structural Characterization of Zinc-Sucrose Complex and Its Ability to Promote Zinc Absorption in Caco-2 Monolayer Cells and Mice.
Li N, Wang R, Deng Z, Zhou J, Li W, Du Q, Zheng L
Journal of agricultural and food chemistry 2023 Aug 9;71(31):12094-12104
Journal of agricultural and food chemistry 2023 Aug 9;71(31):12094-12104
Acetyl-Coenzyme A Synthetase 2 Potentiates Macropinocytosis and Muscle Wasting Through Metabolic Reprogramming in Pancreatic Cancer.
Zhou Z, Ren Y, Yang J, Liu M, Shi X, Luo W, Fung KM, Xu C, Bronze MS, Zhang Y, Houchen CW, Li M
Gastroenterology 2022 Nov;163(5):1281-1293.e1
Gastroenterology 2022 Nov;163(5):1281-1293.e1
RASSF1A independence and early galectin-1 upregulation in PIK3CA-induced hepatocarcinogenesis: new therapeutic venues.
Scheiter A, Evert K, Reibenspies L, Cigliano A, Annweiler K, Müller K, Pöhmerer LM, Xu H, Cui G, Itzel T, Materna-Reichelt S, Coluccio A, Honarnejad K, Teufel A, Brochhausen C, Dombrowski F, Chen X, Evert M, Calvisi DF, Utpatel K
Molecular oncology 2022 Mar;16(5):1091-1118
Molecular oncology 2022 Mar;16(5):1091-1118
Circular RNA ANAPC7 Inhibits Tumor Growth and Muscle Wasting via PHLPP2-AKT-TGF-β Signaling Axis in Pancreatic Cancer.
Shi X, Yang J, Liu M, Zhang Y, Zhou Z, Luo W, Fung KM, Xu C, Bronze MS, Houchen CW, Li M
Gastroenterology 2022 Jun;162(7):2004-2017.e2
Gastroenterology 2022 Jun;162(7):2004-2017.e2
A Novel ZIP4-HDAC4-VEGFA Axis in High-Grade Serous Ovarian Cancer.
Fan Q, Li L, Wang TL, Emerson RE, Xu Y
Cancers 2021 Jul 29;13(15)
Cancers 2021 Jul 29;13(15)
Gene expression microarray analysis of adult testicular germ cell tumor: a comparison between pure-type seminomas and seminoma components in mixed tumors.
Miyai K, Yonekura Y, Ito K, Matsukuma S, Tsuda H
Virchows Archiv : an international journal of pathology 2021 Dec;479(6):1177-1186
Virchows Archiv : an international journal of pathology 2021 Dec;479(6):1177-1186
Zinc Favors Triple-Negative Breast Cancer's Microenvironment Modulation and Cell Plasticity.
Vogel-González M, Musa-Afaneh D, Rivera Gil P, Vicente R
International journal of molecular sciences 2021 Aug 25;22(17)
International journal of molecular sciences 2021 Aug 25;22(17)
ZIP4 promotes non-small cell lung cancer metastasis by activating snail-N-cadherin signaling axis.
Jiang Y, Zhan H, Zhang Y, Yang J, Liu M, Xu C, Fan X, Zhang J, Zhou Z, Shi X, Ramesh R, Li M
Cancer letters 2021 Aug 24;521:71-81
Cancer letters 2021 Aug 24;521:71-81
SLC39A4 as a Novel Prognosis Marker Promotes Tumor Progression in Esophageal Squamous Cell Carcinoma.
Xia C, Chen X, Li J, Chen P
OncoTargets and therapy 2020;13:3999-4008
OncoTargets and therapy 2020;13:3999-4008
ZIP4 Increases Expression of Transcription Factor ZEB1 to Promote Integrin α3β1 Signaling and Inhibit Expression of the Gemcitabine Transporter ENT1 in Pancreatic Cancer Cells.
Liu M, Zhang Y, Yang J, Cui X, Zhou Z, Zhan H, Ding K, Tian X, Yang Z, Fung KA, Edil BH, Postier RG, Bronze MS, Fernandez-Zapico ME, Stemmler MP, Brabletz T, Li YP, Houchen CW, Li M
Gastroenterology 2020 Feb;158(3):679-692.e1
Gastroenterology 2020 Feb;158(3):679-692.e1
ZIP4 Is a Novel Cancer Stem Cell Marker in High-Grade Serous Ovarian Cancer.
Fan Q, Zhang W, Emerson RE, Xu Y
Cancers 2020 Dec 9;12(12)
Cancers 2020 Dec 9;12(12)
A change in the zinc ion concentration reflects the maturation of insulin-producing cells generated from adipose-derived mesenchymal stem cells.
Ohta S, Ikemoto T, Wada Y, Saito Y, Yamada S, Imura S, Morine Y, Shimada M
Scientific reports 2019 Dec 10;9(1):18731
Scientific reports 2019 Dec 10;9(1):18731
Inhibition of ZIP4 reverses epithelial-to-mesenchymal transition and enhances the radiosensitivity in human nasopharyngeal carcinoma cells.
Zeng Q, Liu YM, Liu J, Han J, Guo JX, Lu S, Huang XM, Yi P, Lang JY, Zhang P, Wang CT
Cell death & disease 2019 Aug 5;10(8):588
Cell death & disease 2019 Aug 5;10(8):588
Exosomal zinc transporter ZIP4 promotes cancer growth and is a novel diagnostic biomarker for pancreatic cancer.
Jin H, Liu P, Wu Y, Meng X, Wu M, Han J, Tan X
Cancer science 2018 Sep;109(9):2946-2956
Cancer science 2018 Sep;109(9):2946-2956
ZIP4 Promotes Pancreatic Cancer Progression by Repressing ZO-1 and Claudin-1 through a ZEB1-Dependent Transcriptional Mechanism.
Liu M, Yang J, Zhang Y, Zhou Z, Cui X, Zhang L, Fung KM, Zheng W, Allard FD, Yee EU, Ding K, Wu H, Liang Z, Zheng L, Fernandez-Zapico ME, Li YP, Bronze MS, Morris KT, Postier RG, Houchen CW, Yang J, Li M
Clinical cancer research : an official journal of the American Association for Cancer Research 2018 Jul 1;24(13):3186-3196
Clinical cancer research : an official journal of the American Association for Cancer Research 2018 Jul 1;24(13):3186-3196
The novel ZIP4 regulation and its role in ovarian cancer.
Fan Q, Cai Q, Li P, Wang W, Wang J, Gerry E, Wang TL, Shih IM, Nephew KP, Xu Y
Oncotarget 2017 Oct 27;8(52):90090-90107
Oncotarget 2017 Oct 27;8(52):90090-90107
Hepcidin Attenuates Zinc Efflux in Caco-2 Cells.
Hennigar SR, McClung JP
The Journal of nutrition 2016 Nov;146(11):2167-2173
The Journal of nutrition 2016 Nov;146(11):2167-2173
Influx mechanisms in the embryonic and adult rat choroid plexus: a transcriptome study.
Saunders NR, Dziegielewska KM, Møllgård K, Habgood MD, Wakefield MJ, Lindsay H, Stratzielle N, Ghersi-Egea JF, Liddelow SA
Frontiers in neuroscience 2015;9:123
Frontiers in neuroscience 2015;9:123
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The ZIP4 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human ZIP4. This antibody recognizes human antigen. The ZIP4 antibody has been validated for the following applications: ELISA, WB analysis.
