16912-1-AP
antibody from Proteintech Group
Targeting: CES1
CEH, CES1A1, CES1A2, CES2, HMSE, HMSE1, SES1
Antibody data
- Antibody Data
- Antigen structure
- References [10]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
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Validation data
Reference
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- Product number
- 16912-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#16912-1-AP, RRID:AB_2077500
- Product name
- CES1 antibody
- Antibody type
- Polyclonal
- Description
- CES1 antibody (Cat. #16912-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IF, IHC, WB,ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Comprehensive analysis of ovarian granulosa cell proteomics and phosphoproteomics in PCOS patients without insulin resistance.
Cross-species single-cell transcriptomic analysis reveals divergence of cell composition and functions in mammalian ileum epithelium.
Clock gene Bmal1 controls diurnal rhythms in expression and activity of intestinal carboxylesterase 1.
Melatonin inhibits lipid accumulation to repress prostate cancer progression by mediating the epigenetic modification of CES1.
Significant Down-Regulation of Urea Cycle Generates Clinically Relevant Proteomic Signature in Hepatocellular Carcinoma Patients with Macrovascular Invasion.
ATAD3 gene cluster deletions cause cerebellar dysfunction associated with altered mitochondrial DNA and cholesterol metabolism.
Cisatracurium-induced proliferation impairment and death of colorectal cancer cells, HCT116 is mediated by p53 dependent intrinsic apoptotic pathway in vitro.
Suppression of carboxylesterases by imatinib mediated by the down-regulation of pregnane X receptor.
Multifactorial resistance to aminopeptidase inhibitor prodrug CHR2863 in myeloid leukemia cells: down-regulation of carboxylesterase 1, drug sequestration in lipid droplets and pro-survival activation ERK/Akt/mTOR.
Simultaneous absolute protein quantification of carboxylesterases 1 and 2 in human liver tissue fractions using liquid chromatography-tandem mass spectrometry.
Yang X, Liu P, He H, Qi D, Yan L
Molecular human reproduction 2024 Feb 29;30(3)
Molecular human reproduction 2024 Feb 29;30(3)
Cross-species single-cell transcriptomic analysis reveals divergence of cell composition and functions in mammalian ileum epithelium.
Li H, Wang X, Wang Y, Zhang M, Hong F, Wang H, Cui A, Zhao J, Ji W, Chen YG
Cell regeneration (London, England) 2022 May 5;11(1):19
Cell regeneration (London, England) 2022 May 5;11(1):19
Clock gene Bmal1 controls diurnal rhythms in expression and activity of intestinal carboxylesterase 1.
Chen X, Yu F, Guo X, Su C, Li SS, Wu B
The Journal of pharmacy and pharmacology 2021 Mar 1;73(1):52-59
The Journal of pharmacy and pharmacology 2021 Mar 1;73(1):52-59
Melatonin inhibits lipid accumulation to repress prostate cancer progression by mediating the epigenetic modification of CES1.
Zhou L, Zhang C, Yang X, Liu L, Hu J, Hou Y, Tao H, Sugimura H, Chen Z, Wang L, Chen K
Clinical and translational medicine 2021 Jun;11(6):e449
Clinical and translational medicine 2021 Jun;11(6):e449
Significant Down-Regulation of Urea Cycle Generates Clinically Relevant Proteomic Signature in Hepatocellular Carcinoma Patients with Macrovascular Invasion.
Cao Y, Ding W, Zhang J, Gao Q, Yang H, Cao W, Wang Z, Fang L, Du R
Journal of proteome research 2019 May 3;18(5):2032-2044
Journal of proteome research 2019 May 3;18(5):2032-2044
ATAD3 gene cluster deletions cause cerebellar dysfunction associated with altered mitochondrial DNA and cholesterol metabolism.
Desai R, Frazier AE, Durigon R, Patel H, Jones AW, Dalla Rosa I, Lake NJ, Compton AG, Mountford HS, Tucker EJ, Mitchell ALR, Jackson D, Sesay A, Di Re M, van den Heuvel LP, Burke D, Francis D, Lunke S, McGillivray G, Mandelstam S, Mochel F, Keren B, Jardel C, Turner AM, Ian Andrews P, Smeitink J, Spelbrink JN, Heales SJ, Kohda M, Ohtake A, Murayama K, Okazaki Y, Lombès A, Holt IJ, Thorburn DR, Spinazzola A
Brain : a journal of neurology 2017 Jun 1;140(6):1595-1610
Brain : a journal of neurology 2017 Jun 1;140(6):1595-1610
Cisatracurium-induced proliferation impairment and death of colorectal cancer cells, HCT116 is mediated by p53 dependent intrinsic apoptotic pathway in vitro.
Yabasin IB, Lu Z, Yu JC, Wen Q
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 Jul;91:320-329
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2017 Jul;91:320-329
Suppression of carboxylesterases by imatinib mediated by the down-regulation of pregnane X receptor.
Luo W, Xin Y, Zhao X, Zhang F, Liu C, Fan H, Xi T, Xiong J
British journal of pharmacology 2017 Apr;174(8):700-717
British journal of pharmacology 2017 Apr;174(8):700-717
Multifactorial resistance to aminopeptidase inhibitor prodrug CHR2863 in myeloid leukemia cells: down-regulation of carboxylesterase 1, drug sequestration in lipid droplets and pro-survival activation ERK/Akt/mTOR.
Verbrugge SE, Al M, Assaraf YG, Kammerer S, Chandrupatla DM, Honeywell R, Musters RP, Giovannetti E, O'Toole T, Scheffer GL, Krige D, de Gruijl TD, Niessen HW, Lems WF, Kramer PA, Scheper RJ, Cloos J, Ossenkoppele GJ, Peters GJ, Jansen G
Oncotarget 2016 Feb 2;7(5):5240-57
Oncotarget 2016 Feb 2;7(5):5240-57
Simultaneous absolute protein quantification of carboxylesterases 1 and 2 in human liver tissue fractions using liquid chromatography-tandem mass spectrometry.
Sato Y, Miyashita A, Iwatsubo T, Usui T
Drug metabolism and disposition: the biological fate of chemicals 2012 Jul;40(7):1389-96
Drug metabolism and disposition: the biological fate of chemicals 2012 Jul;40(7):1389-96
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HEK-293 cells were subjected to SDS PAGE followed by western blot with 16912-1-AP(CES1 antibody) at dilution of 1:500
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human liver using 16912-1-AP(CES1 antibody) at dilution of 1:200 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The CES1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human CES1. This antibody recognizes human antigen. The CES1 antibody has been validated for the following applications: ELISA, WB, IHC analysis.