Antibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations
- Western blot [2]
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- Product number
- ABIN394348 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Heart and Neural Crest Derivatives Expressed 2 (HAND2) (AA 135-217) antibody
- Antibody type
- Monoclonal
- Description
- This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
- Reactivity
- Human
- Host
- Mouse
- Epitope
- AA 135-217
- Isotype
- IgG
- Antibody clone number
- 4D9
- Vial size
- 100 μg
- Storage
- Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Submitted references Transcription factor HAND2 mutations in sporadic Chinese patients with congenital heart disease.
Maternal genes and facial clefts in offspring: a comprehensive search for genetic associations in two population-based cleft studies from Scandinavia.
Co-regulated expression of HAND2 and DEIN by a bidirectional promoter with asymmetrical activity in neuroblastoma.
Cardiac neural crest expression of Hand2 regulates outflow and second heart field development.
Hand, an evolutionarily conserved bHLH transcription factor required for Drosophila cardiogenesis and hematopoiesis.
Shen L, Li XF, Shen AD, Wang Q, Liu CX, Guo YJ, Song ZJ, Li ZZ
Chinese medical journal 2010 Jul;123(13):1623-7
Chinese medical journal 2010 Jul;123(13):1623-7
Maternal genes and facial clefts in offspring: a comprehensive search for genetic associations in two population-based cleft studies from Scandinavia.
Jugessur A, Shi M, Gjessing HK, Lie RT, Wilcox AJ, Weinberg CR, Christensen K, Boyles AL, Daack-Hirsch S, Nguyen TT, Christiansen L, Lidral AC, Murray JC
PloS one 2010 Jul 9;5(7):e11493
PloS one 2010 Jul 9;5(7):e11493
Co-regulated expression of HAND2 and DEIN by a bidirectional promoter with asymmetrical activity in neuroblastoma.
Voth H, Oberthuer A, Simon T, Kahlert Y, Berthold F, Fischer M
BMC molecular biology 2009 Apr 6;10:28
BMC molecular biology 2009 Apr 6;10:28
Cardiac neural crest expression of Hand2 regulates outflow and second heart field development.
Morikawa Y, Cserjesi P
Circulation research 2008 Dec 5;103(12):1422-9
Circulation research 2008 Dec 5;103(12):1422-9
Hand, an evolutionarily conserved bHLH transcription factor required for Drosophila cardiogenesis and hematopoiesis.
Han Z, Yi P, Li X, Olson EN
Development (Cambridge, England) 2006 Mar;133(6):1175-82
Development (Cambridge, England) 2006 Mar;133(6):1175-82
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- WB
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- WB