NB300-196

antibody from Novus Biologicals

Targeting: GABRA6

Western blot (Supportive data in Antibodypedia)

Immunocytochemistry (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

NB300-196

Provider

Novus Biologicals

Proper citation

Novus Cat#NB300-196, RRID:AB_10003414

Product name

Rabbit Polyclonal GABA-AR alpha 6 Antibody

Antibody type

Polyclonal

Description

Immunogen affinity purified. Specific for the ~57k alpha 6-subunit of the GABAA receptor in Western blots. Labeling is absent in alpha 6-subunit knockout animals.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Isotype

IgG

Vial size

0.1 ml

Concentration

0.2 mg/ml

Storage

Store at -20C. Avoid freeze-thaw cycles.

References

Submitted references

The α6 subunit-containing GABA(A) receptor: A novel drug target for inhibition of trigeminal activation.

Fan PC, Lai TH, Hor CC, Lee MT, Huang P, Sieghart W, Ernst M, Knutson DE, Cook J, Chiou LC
Neuropharmacology 2018 Sep 15;140:1-13

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Differential effects of methylmercury on gamma-aminobutyric acid type A receptor currents in rat cerebellar granule and cerebral cortical neurons in culture.

Herden CJ, Pardo NE, Hajela RK, Yuan Y, Atchison WD
The Journal of pharmacology and experimental therapeutics 2008 Feb;324(2):517-28

Western blot

Supportive validation

Submitted by

Novus Biologicals (provider)

Main image

Experimental details

Western Blot: GABA-A R alpha 6 Antibody [NB300-196] - Analysis of mouse forebrain lysates from Wild Type (Control) and a6-knockout (a6-K/O) animals showing specific immunolabeling of the ~57k a6-subunit of the GABAA-R. The labeling was absent from a lysate prepared from a6-knockout animals.

Supportive validation

Submitted by

Novus Biologicals (provider)

Main image

Experimental details

Western Blot: GABA A Receptor alpha 6 Antibody [NB300-196] - Detection of GABA-A alpha 6 receptor in wildtype cerebellum (5-7 ug/lane).