ABIN152544

antibody from antibodies-online

Targeting: HIP1 ILWEQ

Western blot (Supportive data in Antibodypedia)

Immunocytochemistry (Recommended by provider)

Immunoprecipitation (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Chromatin Immunoprecipitation (Recommended by provider)

Antibody Data

Product number

ABIN152544

Provider

antibodies-online

Product name

anti-Huntingtin Interacting Protein 1 (HIP1) antibody

Antibody type

Monoclonal

Description

Unpurified

Reactivity

Human, Mouse

Host

Mouse

Isotype

IgG

Antibody clone number

4B10

Vial size

0.1 mL

Storage

Aliquot and store at -20°C or -80°C. Avoid freeze-thaw cycles.

Handling

Avoid freeze-thaw cycles

References

Submitted references

Replacement of charged and polar residues in the coiled-coiled interface of huntingtin-interacting protein 1 (HIP1) causes aggregation and cell death.

Fontaine SN, Bauer SP, Lin X, Poorfarahani S, Ybe JA
FEBS letters 2012 Sep 21;586(19):3030-6

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G protein-coupled receptor kinase 5 phosphorylation of hip regulates internalization of the chemokine receptor CXCR4.

Barker BL, Benovic JL
Biochemistry 2011 Aug 16;50(32):6933-41

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Aberrant Huntingtin interacting protein 1 in lymphoid malignancies.

Bradley SV, Smith MR, Hyun TS, Lucas PC, Li L, Antonuk D, Joshi I, Jin F, Ross TS
Cancer research 2007 Sep 15;67(18):8923-31

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Huntingtin interacting protein 1 is a novel brain tumor marker that associates with epidermal growth factor receptor.

Bradley SV, Holland EC, Liu GY, Thomas D, Hyun TS, Ross TS
Cancer research 2007 Apr 15;67(8):3609-15

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Serum antibodies to huntingtin interacting protein-1: a new blood test for prostate cancer.

Bradley SV, Oravecz-Wilson KI, Bougeard G, Mizukami I, Li L, Munaco AJ, Sreekumar A, Corradetti MN, Chinnaiyan AM, Sanda MG, Ross TS
Cancer research 2005 May 15;65(10):4126-33

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Huntingtin interacting protein 1 modulates the transcriptional activity of nuclear hormone receptors.

Mills IG, Gaughan L, Robson C, Ross T, McCracken S, Kelly J, Neal DE
The Journal of cell biology 2005 Jul 18;170(2):191-200

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HIP1 and HIP1r stabilize receptor tyrosine kinases and bind 3-phosphoinositides via epsin N-terminal homology domains.

Hyun TS, Rao DS, Saint-Dic D, Michael LE, Kumar PD, Bradley SV, Mizukami IF, Oravecz-Wilson KI, Ross TS
The Journal of biological chemistry 2004 Apr 2;279(14):14294-306

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Huntingtin-interacting protein 1 is overexpressed in prostate and colon cancer and is critical for cellular survival.

Rao DS, Hyun TS, Kumar PD, Mizukami IF, Rubin MA, Lucas PC, Sanda MG, Ross TS
The Journal of clinical investigation 2002 Aug;110(3):351-60

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Huntingtin interacting protein 1 Is a clathrin coat binding protein required for differentiation of late spermatogenic progenitors.

Rao DS, Chang JC, Kumar PD, Mizukami I, Smithson GM, Bradley SV, Parlow AF, Ross TS
Molecular and cellular biology 2001 Nov;21(22):7796-806

Western blot

Supportive validation

Submitted by

antibodies-online (provider)

Main image

Experimental details

WB