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- Antibody Data
- Antigen structure
- References [13]
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- Validations
- Western blot [1]
- Immunoprecipitation [1]
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- Product number
- 11188-2-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#11188-2-AP, RRID:AB_2064971
- Product name
- BBS2 antibody
- Antibody type
- Polyclonal
- Description
- BBS2 antibody (Cat. #11188-2-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references POMC Neuron BBSome Regulation of Body Weight is Independent of its Ciliary Function.
Genetic interaction of mammalian IFT-A paralogs regulates cilia disassembly, ciliary entry of membrane protein, Hedgehog signaling, and embryogenesis.
Ubiquitin links smoothened to intraflagellar transport to regulate Hedgehog signaling.
Single-particle tracking localization microscopy reveals nonaxonemal dynamics of intraflagellar transport proteins at the base of mammalian primary cilia.
Inhibition of Hedgehog signaling suppresses proliferation and microcyst formation of human Autosomal Dominant Polycystic Kidney Disease cells.
Refining genotype-phenotype correlation in Alström syndrome through study of primary human fibroblasts.
A novel form of ciliopathy underlies hyperphagia and obesity in Ankrd26 knockout mice.
Essential role of the chaperonin CCT in rod outer segment biogenesis.
A truncating mutation of Alms1 reduces the number of hypothalamic neuronal cilia in obese mice.
Asymmetric segregation of the double-stranded RNA binding protein Staufen2 during mammalian neural stem cell divisions promotes lineage progression.
The conserved Bardet-Biedl syndrome proteins assemble a coat that traffics membrane proteins to cilia.
Patterns of expression of Bardet-Biedl syndrome proteins in the mammalian cochlea suggest noncentrosomal functions.
Essential role of nephrocystin in photoreceptor intraflagellar transport in mouse.
Guo DF, Williams PA, Laule C, Seaby C, Zhang Q, Sheffield VC, Rahmouni K
Function (Oxford, England) 2024;5(1):zqad070
Function (Oxford, England) 2024;5(1):zqad070
Genetic interaction of mammalian IFT-A paralogs regulates cilia disassembly, ciliary entry of membrane protein, Hedgehog signaling, and embryogenesis.
Wang W, Allard BA, Pottorf TS, Wang HH, Vivian JL, Tran PV
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 May;34(5):6369-6381
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2020 May;34(5):6369-6381
Ubiquitin links smoothened to intraflagellar transport to regulate Hedgehog signaling.
Desai PB, Stuck MW, Lv B, Pazour GJ
The Journal of cell biology 2020 Jul 6;219(7)
The Journal of cell biology 2020 Jul 6;219(7)
Single-particle tracking localization microscopy reveals nonaxonemal dynamics of intraflagellar transport proteins at the base of mammalian primary cilia.
Yang TT, Tran MNT, Chong WM, Huang CE, Liao JC
Molecular biology of the cell 2019 Mar 21;30(7):828-837
Molecular biology of the cell 2019 Mar 21;30(7):828-837
Inhibition of Hedgehog signaling suppresses proliferation and microcyst formation of human Autosomal Dominant Polycystic Kidney Disease cells.
Silva LM, Jacobs DT, Allard BA, Fields TA, Sharma M, Wallace DP, Tran PV
Scientific reports 2018 Mar 21;8(1):4985
Scientific reports 2018 Mar 21;8(1):4985
Refining genotype-phenotype correlation in Alström syndrome through study of primary human fibroblasts.
Chen JH, Geberhiwot T, Barrett TG, Paisey R, Semple RK
Molecular genetics & genomic medicine 2017 Jul;5(4):390-404
Molecular genetics & genomic medicine 2017 Jul;5(4):390-404
A novel form of ciliopathy underlies hyperphagia and obesity in Ankrd26 knockout mice.
Acs P, Bauer PO, Mayer B, Bera T, Macallister R, Mezey E, Pastan I
Brain structure & function 2015;220(3):1511-28
Brain structure & function 2015;220(3):1511-28
Essential role of the chaperonin CCT in rod outer segment biogenesis.
Sinha S, Belcastro M, Datta P, Seo S, Sokolov M
Investigative ophthalmology & visual science 2014 May 22;55(6):3775-85
Investigative ophthalmology & visual science 2014 May 22;55(6):3775-85
A truncating mutation of Alms1 reduces the number of hypothalamic neuronal cilia in obese mice.
Heydet D, Chen LX, Larter CZ, Inglis C, Silverman MA, Farrell GC, Leroux MR
Developmental neurobiology 2013 Jan;73(1):1-13
Developmental neurobiology 2013 Jan;73(1):1-13
Asymmetric segregation of the double-stranded RNA binding protein Staufen2 during mammalian neural stem cell divisions promotes lineage progression.
Kusek G, Campbell M, Doyle F, Tenenbaum SA, Kiebler M, Temple S
Cell stem cell 2012 Oct 5;11(4):505-16
Cell stem cell 2012 Oct 5;11(4):505-16
The conserved Bardet-Biedl syndrome proteins assemble a coat that traffics membrane proteins to cilia.
Jin H, White SR, Shida T, Schulz S, Aguiar M, Gygi SP, Bazan JF, Nachury MV
Cell 2010 Jun 25;141(7):1208-19
Cell 2010 Jun 25;141(7):1208-19
Patterns of expression of Bardet-Biedl syndrome proteins in the mammalian cochlea suggest noncentrosomal functions.
May-Simera HL, Ross A, Rix S, Forge A, Beales PL, Jagger DJ
The Journal of comparative neurology 2009 May 10;514(2):174-88
The Journal of comparative neurology 2009 May 10;514(2):174-88
Essential role of nephrocystin in photoreceptor intraflagellar transport in mouse.
Jiang ST, Chiou YY, Wang E, Chien YL, Ho HH, Tsai FJ, Lin CY, Tsai SP, Li H
Human molecular genetics 2009 May 1;18(9):1566-77
Human molecular genetics 2009 May 1;18(9):1566-77
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse testis tissue were subjected to SDS PAGE followed by western blot with 11188-2-AP(BBS2 antibody) at dilution of 1:500
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- IP Result of anti-BBS2 (IP:11188-2-AP, 5ug; Detection:11188-2-AP 1:500) with mouse liver tissue lysate 6000ug.
- Sample type
- tissue
