Antibody data
- Antibody Data
- Antigen structure
- References [23]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- 14104-1-AP - Provider product page

- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#14104-1-AP, RRID:AB_10693527
- Product name
- GABRG2 antibody
- Antibody type
- Polyclonal
- Description
- GABRG2 antibody (Cat. #14104-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, IF, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Increased excitability of layer 5 neocortical pyramidal neurons and its contribution to seizure activity in Gabrg2 gene-deficient mice.
Decorin Attenuates Epileptogenesis and Modulates Hippocampal Synaptic Plasticity via the mTOR Signalling Pathway.
Parishin from Gastrodia elata ameliorates DSS induced colitis and anxiety-like behavior in mice by regulating intestinal barrier function and microviota-gut-brain axis.
MicroRNA-502-3p Modulates the GABA A Subunits, Synaptic Proteins, and Mitochondrial Morphology in Hippocampal Neurons.
Ectoparasites enhance survival by suppressing host exploration and limiting dispersal.
Promotion of sleep by cinnamic acid in parachlorophenylalanine-induced insomnia in rats.
Inferred developmental origins of brain tumors from single-cell RNA-sequencing data.
MicroRNA-502-3p modulates the GABA A subunits, synaptic proteins and mitochondrial morphology in hippocampal neurons.
Identification of New Ciliary Signaling Pathways in the Brain and Insights into Neurological Disorders.
Long-term aerobic exercise improves learning memory capacity and effects on oxidative stress levels and Keap1/Nrf2/GPX4 pathway in the hippocampus of APP/PS1 mice.
Activation of nuclear receptor pregnane-X-receptor protects against abdominal aortic aneurysm by inhibiting oxidative stress.
The Traf2 and NcK interacting kinase inhibitor NCB-0846 suppresses seizure activity involving the decrease of GRIA1.
Mice harboring the T316N variant in the GABA(A)R γ(2) subunit exhibit sleep-related hypermotor epilepsy phenotypes and hypersynchronization in the thalamocortical pathway.
Differential Expression of GABA Receptor-Related Genes in Alzheimer's Disease and the Positive Regulatory Role of Aerobic Exercise-From Genetic Screening to D-gal-induced AD-like Pathology Model.
Altered GnRH neuron and ovarian innervation characterize reproductive dysfunction linked to the Fragile X messenger ribonucleoprotein (Fmr1) gene mutation.
A role of GABA(A) receptor α1 subunit in the hippocampus for rapid-acting antidepressant-like effects of ketamine.
Identification of new ciliary signaling pathways in the brain and insights into neurological disorders.
Increased body weight in mice with fragile X messenger ribonucleoprotein 1 (Fmr1) gene mutation is associated with hypothalamic dysfunction.
Pan-cancer analysis identifies tumor-specific antigens derived from transposable elements.
MRI Characteristics of Autoimmune Encephalitis With Autoantibodies to GABAA Receptor: A Case Series.
STK24 modulates excitatory synaptic transmission in epileptic hippocampal neurons.
Transgenic overexpression of furin increases epileptic susceptibility.
Acupuncture improves locomotor function by enhancing GABA receptor expression in transient focal cerebral ischemia rats.
Sun Y, Li Z, Yu B, Zhang C, Wang L, Guo B, Ding J, Xiao L, Gao P, Li X, Sun T
iScience 2026 Jan 16;29(1):114421
iScience 2026 Jan 16;29(1):114421
Decorin Attenuates Epileptogenesis and Modulates Hippocampal Synaptic Plasticity via the mTOR Signalling Pathway.
Liu Z, Shen Y, Luo AD, Ao WL, Guan SQ, Lei F, Xu ZC, Yu CY, Xu P, Huang H
Neurochemical research 2026 Feb 17;51(2):74
Neurochemical research 2026 Feb 17;51(2):74
Parishin from Gastrodia elata ameliorates DSS induced colitis and anxiety-like behavior in mice by regulating intestinal barrier function and microviota-gut-brain axis.
Liu X, Zhou H, Yang N, Yang LJ, Zi ZY, Han YL, He J, Su LY
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Sep;145:157019
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Sep;145:157019
MicroRNA-502-3p Modulates the GABA A Subunits, Synaptic Proteins, and Mitochondrial Morphology in Hippocampal Neurons.
Sharma B, Rodarte D, Goyal G, Rodriguez S, Kumar S
Molecular neurobiology 2025 Oct;62(10):13479-13499
Molecular neurobiology 2025 Oct;62(10):13479-13499
Ectoparasites enhance survival by suppressing host exploration and limiting dispersal.
Liu P, Ren D, Li G, Xu X, Presotto L, Liu W, Zhao N, Li D, Chen M, Wang J, Liu X, Zhao C, Lu L, Liu Q
Nature communications 2025 May 9;16(1):4318
Nature communications 2025 May 9;16(1):4318
Promotion of sleep by cinnamic acid in parachlorophenylalanine-induced insomnia in rats.
Ye X, Sun C, Zhao Y, Wang W, Li Z, Liu L, Han X
International immunopharmacology 2025 Jun 17;158:114852
International immunopharmacology 2025 Jun 17;158:114852
Inferred developmental origins of brain tumors from single-cell RNA-sequencing data.
Wang S, Curry RN, McDonald MF, Koh HY, Erickson AW, Kleinman CL, Taylor MD, Rao G, Deneen B, Harmanci AO, Serin Harmanci A
Neuro-oncology advances 2025 Jan-Dec;7(1):vdaf016
Neuro-oncology advances 2025 Jan-Dec;7(1):vdaf016
MicroRNA-502-3p modulates the GABA A subunits, synaptic proteins and mitochondrial morphology in hippocampal neurons.
Sharma B, Rodarte D, Goyal G, Rodriguez S, Kumar S
bioRxiv : the preprint server for biology 2025 Jan 13;
bioRxiv : the preprint server for biology 2025 Jan 13;
Identification of New Ciliary Signaling Pathways in the Brain and Insights into Neurological Disorders.
Loukil A, Ebright E, Hamdi K, Menzel E, Uezu A, Gao Y, Soderling SH, Goetz SC
The Journal of neuroscience : the official journal of the Society for Neuroscience 2025 Aug 13;45(33)
The Journal of neuroscience : the official journal of the Society for Neuroscience 2025 Aug 13;45(33)
Long-term aerobic exercise improves learning memory capacity and effects on oxidative stress levels and Keap1/Nrf2/GPX4 pathway in the hippocampus of APP/PS1 mice.
Wang S, Zhou Y, Wu Y, Lang Y, Mao Y, Pan G, Gao Z
Frontiers in neuroscience 2024;18:1505650
Frontiers in neuroscience 2024;18:1505650
Activation of nuclear receptor pregnane-X-receptor protects against abdominal aortic aneurysm by inhibiting oxidative stress.
Shen Z, Wang J, Chen Y, Fang P, Yuan A, Chen AF, Yan X, Lyu Y, Pu J
Redox biology 2024 Nov;77:103397
Redox biology 2024 Nov;77:103397
The Traf2 and NcK interacting kinase inhibitor NCB-0846 suppresses seizure activity involving the decrease of GRIA1.
Wang M, Gu Y, Li Q, Feng B, Lv X, Zhang H, Kong Q, Dong Z, Tian X, Zhang Y
Genes & diseases 2024 May;11(3):100997
Genes & diseases 2024 May;11(3):100997
Mice harboring the T316N variant in the GABA(A)R γ(2) subunit exhibit sleep-related hypermotor epilepsy phenotypes and hypersynchronization in the thalamocortical pathway.
Jiang YL, Xia L, Zhao JJ, Zhou HM, Mi D, Wang X, Wang YY, Song CG, Jiang W
Experimental neurology 2024 Jun;376:114775
Experimental neurology 2024 Jun;376:114775
Differential Expression of GABA Receptor-Related Genes in Alzheimer's Disease and the Positive Regulatory Role of Aerobic Exercise-From Genetic Screening to D-gal-induced AD-like Pathology Model.
Liu Y, Peng H, Liu Q, Hao J, Tang C, Yan H
Neuromolecular medicine 2024 Dec 19;27(1):1
Neuromolecular medicine 2024 Dec 19;27(1):1
Altered GnRH neuron and ovarian innervation characterize reproductive dysfunction linked to the Fragile X messenger ribonucleoprotein (Fmr1) gene mutation.
Villa PA, Lainez NM, Jonak CR, Berlin SC, Ethell IM, Coss D
Frontiers in endocrinology 2023;14:1129534
Frontiers in endocrinology 2023;14:1129534
A role of GABA(A) receptor α1 subunit in the hippocampus for rapid-acting antidepressant-like effects of ketamine.
Tang XH, Diao YG, Ren ZY, Zang YY, Zhang GF, Wang XM, Duan GF, Shen JC, Hashimoto K, Zhou ZQ, Yang JJ
Neuropharmacology 2023 Mar 1;225:109383
Neuropharmacology 2023 Mar 1;225:109383
Identification of new ciliary signaling pathways in the brain and insights into neurological disorders.
Loukil A, Ebright E, Uezu A, Gao Y, Soderling SH, Goetz SC
bioRxiv : the preprint server for biology 2023 Dec 21;
bioRxiv : the preprint server for biology 2023 Dec 21;
Increased body weight in mice with fragile X messenger ribonucleoprotein 1 (Fmr1) gene mutation is associated with hypothalamic dysfunction.
Ruggiero-Ruff RE, Villa PA, Hijleh SA, Avalos B, DiPatrizio NV, Haga-Yamanaka S, Coss D
Scientific reports 2023 Aug 4;13(1):12666
Scientific reports 2023 Aug 4;13(1):12666
Pan-cancer analysis identifies tumor-specific antigens derived from transposable elements.
Shah NM, Jang HJ, Liang Y, Maeng JH, Tzeng SC, Wu A, Basri NL, Qu X, Fan C, Li A, Katz B, Li D, Xing X, Evans BS, Wang T
Nature genetics 2023 Apr;55(4):631-639
Nature genetics 2023 Apr;55(4):631-639
MRI Characteristics of Autoimmune Encephalitis With Autoantibodies to GABAA Receptor: A Case Series.
Deng B, Cai M, Qiu Y, Liu X, Yu H, Zhang X, Huang H, Zhao X, Yang W, Dong S, Jin L, Chu S, Chen X
Neurology(R) neuroimmunology & neuroinflammation 2022 May;9(3)
Neurology(R) neuroimmunology & neuroinflammation 2022 May;9(3)
STK24 modulates excitatory synaptic transmission in epileptic hippocampal neurons.
Yang J, Jiang Q, Yu X, Xu T, Wang Y, Deng J, Liu Y, Chen Y
CNS neuroscience & therapeutics 2020 Aug;26(8):851-861
CNS neuroscience & therapeutics 2020 Aug;26(8):851-861
Transgenic overexpression of furin increases epileptic susceptibility.
Yang Y, He M, Tian X, Guo Y, Liu F, Li Y, Zhang H, Lu X, Xu D, Zhou R, Ma Y, Wang W, Chen G, Hu Y, Wang X
Cell death & disease 2018 Oct 17;9(11):1058
Cell death & disease 2018 Oct 17;9(11):1058
Acupuncture improves locomotor function by enhancing GABA receptor expression in transient focal cerebral ischemia rats.
Xu Q, Yang JW, Cao Y, Zhang LW, Zeng XH, Li F, Du SQ, Wang LP, Liu CZ
Neuroscience letters 2015 Feb 19;588:88-94
Neuroscience letters 2015 Feb 19;588:88-94
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- The GABRG2 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human GABRG2. This antibody recognizes human,mouse,rat antigen. The GABRG2 antibody has been validated for the following applications: ELISA, WB, IF analysis.