Antibody data
- Antibody Data
- Antigen structure
- References [10]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
Reference
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- Product number
- NB300-190 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NB300-190, RRID:AB_2294344
- Product name
- Rabbit Polyclonal GABA-A R gamma 2 Antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified. Specific for the ~46k gamma2-subunit of the GABAA receptor in Western blots.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 0.1 ml
- Concentration
- 0.15 mg/ml
- Storage
- Store at -20C. Avoid freeze-thaw cycles.
Submitted references The X-Linked Intellectual Disability Gene Zdhhc9 Is Essential for Dendrite Outgrowth and Inhibitory Synapse Formation.
Metformin produces anxiolytic-like effects in rats by facilitating GABA(A) receptor trafficking to membrane.
The Contribution of Normal Pregnancy to Eclampsia.
GABAergic projections from lateral hypothalamus to paraventricular hypothalamic nucleus promote feeding.
Brief Dark Exposure Reduces Tonic Inhibition in Visual Cortex.
Altered GABAA receptor expression and seizure threshold following acute ethanol challenge in mice lacking the RIIβ subunit of PKA.
Downregulation of GABAA receptor protein subunits α6, β2, δ, ε, γ2, θ, and ρ2 in superior frontal cortex of subjects with autism.
Spatial relationships between GABAergic and glutamatergic synapses on the dendrites of distinct types of mouse retinal ganglion cells across development.
Alterations of GABA(A) and glutamate receptor subunits and heat shock protein in rat hippocampus following traumatic brain injury and in posttraumatic epilepsy.
A mouse monoclonal antibody against the γ2 subunit of GABAA receptors.
Shimell JJ, Shah BS, Cain SM, Thouta S, Kuhlmann N, Tatarnikov I, Jovellar DB, Brigidi GS, Kass J, Milnerwood AJ, Snutch TP, Bamji SX
Cell reports 2019 Nov 19;29(8):2422-2437.e8
Cell reports 2019 Nov 19;29(8):2422-2437.e8
Metformin produces anxiolytic-like effects in rats by facilitating GABA(A) receptor trafficking to membrane.
Fan J, Li D, Chen HS, Huang JG, Xu JF, Zhu WW, Chen JG, Wang F
British journal of pharmacology 2019 Jan;176(2):297-316
British journal of pharmacology 2019 Jan;176(2):297-316
The Contribution of Normal Pregnancy to Eclampsia.
Johnson AC, Nagle KJ, Tremble SM, Cipolla MJ
PloS one 2015;10(7):e0133953
PloS one 2015;10(7):e0133953
GABAergic projections from lateral hypothalamus to paraventricular hypothalamic nucleus promote feeding.
Wu Z, Kim ER, Sun H, Xu Y, Mangieri LR, Li DP, Pan HL, Xu Y, Arenkiel BR, Tong Q
The Journal of neuroscience : the official journal of the Society for Neuroscience 2015 Feb 25;35(8):3312-8
The Journal of neuroscience : the official journal of the Society for Neuroscience 2015 Feb 25;35(8):3312-8
Brief Dark Exposure Reduces Tonic Inhibition in Visual Cortex.
Huang S, Hokenson K, Bandyopadhyay S, Russek SJ, Kirkwood A
The Journal of neuroscience : the official journal of the Society for Neuroscience 2015 Dec 2;35(48):15916-20
The Journal of neuroscience : the official journal of the Society for Neuroscience 2015 Dec 2;35(48):15916-20
Altered GABAA receptor expression and seizure threshold following acute ethanol challenge in mice lacking the RIIβ subunit of PKA.
Carlson SL, O'Buckley TK, Thomas R, Thiele TE, Morrow AL
Neurochemical research 2014 Jun;39(6):1079-87
Neurochemical research 2014 Jun;39(6):1079-87
Downregulation of GABAA receptor protein subunits α6, β2, δ, ε, γ2, θ, and ρ2 in superior frontal cortex of subjects with autism.
Fatemi SH, Reutiman TJ, Folsom TD, Rustan OG, Rooney RJ, Thuras PD
Journal of autism and developmental disorders 2014 Aug;44(8):1833-45
Journal of autism and developmental disorders 2014 Aug;44(8):1833-45
Spatial relationships between GABAergic and glutamatergic synapses on the dendrites of distinct types of mouse retinal ganglion cells across development.
Bleckert A, Parker ED, Kang Y, Pancaroglu R, Soto F, Lewis R, Craig AM, Wong RO
PloS one 2013;8(7):e69612
PloS one 2013;8(7):e69612
Alterations of GABA(A) and glutamate receptor subunits and heat shock protein in rat hippocampus following traumatic brain injury and in posttraumatic epilepsy.
Kharlamov EA, Lepsveridze E, Meparishvili M, Solomonia RO, Lu B, Miller ER, Kelly KM, Mtchedlishvili Z
Epilepsy research 2011 Jun;95(1-2):20-34
Epilepsy research 2011 Jun;95(1-2):20-34
A mouse monoclonal antibody against the γ2 subunit of GABAA receptors.
Joshi S, Sun C, Kapur J
Hybridoma (2005) 2011 Dec;30(6):537-42
Hybridoma (2005) 2011 Dec;30(6):537-42
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: GABA-A R gamma 2 Antibody [NB300-190] - Mouse whole brain lysate showing specific immunolabeling of the ~46 kDa gamma-2-subunit of GABAa -R.
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry: GABA-A R gamma 2 Antibody [NB300-190] - Immunostaining of mouse retina showing specific labeling of the GABAa gamma-2 subunit in green, calbindin in red and DNA in blue. Photo courtesy of Dr. Arlene Hirano, UCLA.