ABIN372642

antibody from antibodies-online

Targeting: GABRG2

Western blot (Recommended by provider)

Antibody Data

Product number

ABIN372642

Provider

antibodies-online

Product name

anti-gamma-aminobutyric Acid (GABA) A Receptor, gamma 2 (GABRG2) (pSer327) antibody

Antibody type

Polyclonal

Antigen

Phosphopeptide corresponding to amino acid residues surrounding the phospho-Ser327 of the GABAA Receptor, Gamma2 subunit.

Description

Sequential Chromatography on phospho- and dephospho-peptide affinity columns.

Reactivity

Human, Mouse, Rat, Bovine, Canine, Chicken/Avian

Host

Rabbit

Epitope

pSer327

Isotype

IgG

Vial size

0.1 mL

Storage

Store the antibody undiluted (in aliquots) at-20°C.

Handling

Avoid repeated freezing and thawing.

References

Submitted references

Protein kinase C epsilon regulates gamma-aminobutyrate type A receptor sensitivity to ethanol and benzodiazepines through phosphorylation of gamma2 subunits.

Qi ZH, Song M, Wallace MJ, Wang D, Newton PM, McMahon T, Chou WH, Zhang C, Shokat KM, Messing RO
The Journal of biological chemistry 2007 Nov 9;282(45):33052-63

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Affinity of various benzodiazepine site ligands in mice with a point mutation in the GABA(A) receptor gamma2 subunit.

Ogris W, Pöltl A, Hauer B, Ernst M, Oberto A, Wulff P, Höger H, Wisden W, Sieghart W
Biochemical pharmacology 2004 Oct 15;68(8):1621-9

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Molecular and functional diversity of the expanding GABA-A receptor gene family.

Whiting PJ, Bonnert TP, McKernan RM, Farrar S, Le Bourdellès B, Heavens RP, Smith DW, Hewson L, Rigby MR, Sirinathsinghji DJ, Thompson SA, Wafford KA
Annals of the New York Academy of Sciences 1999 Apr 30;868:645-53

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Molecular biology of GABAA receptors.

Olsen RW, Tobin AJ
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1990 Mar;4(5):1469-80