orb2636867

antibody from Biorbyt
Targeting: ZBTB46 BTBD4, BZEL, FLJ13502, RINZF, ZNF340
Provider product page for orb2636867
Western blot
Immunocytochemistry
Immunohistochemistry
Flow cytometry

Antibody data

Product number
orb2636867 - Provider product page
Provider
Biorbyt
Product name
ZBTB46 Antibody / BTBD4 / ZNF340
Antibody type
Monoclonal
Description
BTBD4 (BTB/POZ domain-containing protein 4), also known as zinc finger protein 340 (ZNF340) or zinc finger and BTB domain-containing protein 46 (ZBTB46), is a 589 amino acid protein that contains one BTB/POZ domain. The BTB/POZ domain mediates homomeric and heteromeric POZ-POZ inter- actions and is common to transcriptional regulators involved in chromatin modeling. In several BTB/POZ containing proteins, including BCL-6 and the promyelocytic leukemia zinc-finger (PLZF) oncoprotein, this domain interacts with the SMRT/N-CoR-mSin3A HDAC complex and is directly involved in repressing and silencing gene transcription. When this domain is deleted, as with the oncogenic PLZF-RAR chimera of promyelocytic leukemias, this tran- scriptional repression is attenuated. This suggests that BTBD4 may play a role in transcription regulation.
Reactivity
Human
Host
Mouse
Conjugate
Unconjugated
Antibody clone number
PCRP-ZBTB46-2B8
Vial size
20 ug
Storage
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
ZBTB46 protein structure - orb2636867 shown in red.