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- Antibody Data
- Antigen structure
- References [5]
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- Validations
- Western blot [1]
- Immunohistochemistry [2]
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- Product number
- 14069-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#14069-1-AP, RRID:AB_2296187
- Product name
- INTS5 antibody
- Antibody type
- Polyclonal
- Description
- INTS5 antibody (Cat. #14069-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references INTAC endonuclease and phosphatase modules differentially regulate transcription by RNA polymerase II.
A combinatorial approach to uncover an additional Integrator subunit.
INTS13 variants causing a recessive developmental ciliopathy disrupt assembly of the Integrator complex.
RPAP2 regulates a transcription initiation checkpoint by inhibiting assembly of pre-initiation complex.
Identification of Integrator-PP2A complex (INTAC), an RNA polymerase II phosphatase.
Hu S, Peng L, Song A, Ji YX, Cheng J, Wang M, Chen FX
Molecular cell 2023 May 18;83(10):1588-1604.e5
Molecular cell 2023 May 18;83(10):1588-1604.e5
A combinatorial approach to uncover an additional Integrator subunit.
Offley SR, Pfleiderer MM, Zucco A, Fraudeau A, Welsh SA, Razew M, Galej WP, Gardini A
Cell reports 2023 Mar 28;42(3):112244
Cell reports 2023 Mar 28;42(3):112244
INTS13 variants causing a recessive developmental ciliopathy disrupt assembly of the Integrator complex.
Mascibroda LG, Shboul M, Elrod ND, Colleaux L, Hamamy H, Huang KL, Peart N, Singh MK, Lee H, Merriman B, Jodoin JN, Sitaram P, Lee LA, Fathalla R, Al-Rawashdeh B, Ababneh O, El-Khateeb M, Escande-Beillard N, Nelson SF, Wu Y, Tong L, Kenney LJ, Roy S, Russell WK, Amiel J, Reversade B, Wagner EJ
Nature communications 2022 Oct 13;13(1):6054
Nature communications 2022 Oct 13;13(1):6054
RPAP2 regulates a transcription initiation checkpoint by inhibiting assembly of pre-initiation complex.
Wang X, Qi Y, Wang Z, Wang L, Song A, Tao B, Li J, Zhao D, Zhang H, Jin Q, Jiang YZ, Chen FX, Xu Y, Chen X
Cell reports 2022 Apr 26;39(4):110732
Cell reports 2022 Apr 26;39(4):110732
Identification of Integrator-PP2A complex (INTAC), an RNA polymerase II phosphatase.
Zheng H, Qi Y, Hu S, Cao X, Xu C, Yin Z, Chen X, Li Y, Liu W, Li J, Wang J, Wei G, Liang K, Chen FX, Xu Y
Science (New York, N.Y.) 2020 Nov 27;370(6520)
Science (New York, N.Y.) 2020 Nov 27;370(6520)
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- human brain tissue were subjected to SDS PAGE followed by western blot with 14069-1-AP(INTS5 antibody) at dilution of 1:500
- Sample type
- tissue
Supportive validation
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The INTS5 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human INTS5. This antibody recognizes human, mouse, rat antigen. The INTS5 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human prostate cancer using 14069-1-AP(INTS5 antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
