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- Antigen structure
- References [21]
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- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunohistochemistry [2]
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- Product number
- 15952-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#15952-1-AP, RRID:AB_10637268
- Product name
- MAT2B antibody
- Antibody type
- Polyclonal
- Description
- MAT2B antibody (Cat. #15952-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references A role for protein arginine methyltransferase 7 in repetitive and mild traumatic brain injury.
Progesterone and interferon tau regulate expression of polyamine enzymes during the ovine peri-implantation period†.
Mutant CHCHD10 causes an extensive metabolic rewiring that precedes OXPHOS dysfunction in a murine model of mitochondrial cardiomyopathy.
mTORC1 stimulates cell growth through SAM synthesis and m(6)A mRNA-dependent control of protein synthesis.
Grandmaternal betaine supplementation enhances hepatic IGF2 expression in F2 rat offspring through modification of promoter DNA methylation.
Dietary betaine improves egg-laying rate in hens through hypomethylation and glucocorticoid receptor-mediated activation of hepatic lipogenesis-related genes.
Maternal betaine supplementation decreases hepatic cholesterol deposition in chicken offspring with epigenetic modulation of SREBP2 and CYP7A1 genes.
Mitotically Stable Modification of DNA Methylation in IGF2/H19 Imprinting Control Region Is Associated with Activated Hepatic IGF2 Expression in Offspring Rats from Betaine-Supplemented Dams.
Corticosterone-Induced Lipogenesis Activation and Lipophagy Inhibition in Chicken Liver Are Alleviated by Maternal Betaine Supplementation.
Maternal betaine supplementation attenuates glucocorticoid-induced hepatic lipid accumulation through epigenetic modification in adult offspring rats.
Maternal betaine administration modulates hepatic type 1 iodothyronine deiodinase (Dio1) expression in chicken offspring through epigenetic modifications.
Metabolic adaptation of short-living growth hormone transgenic mice to methionine restriction and supplementation.
Ligustrazine modulates renal cysteine biosynthesis in rats exposed to cadmium.
Prenatal betaine exposure modulates hypothalamic expression of cholesterol metabolic genes in cockerels through modifications of DNA methylation.
In ovo injection of betaine alleviates corticosterone-induced fatty liver in chickens through epigenetic modifications.
Folate deprivation induces cell cycle arrest at G0/G1 phase and apoptosis in hippocampal neuron cells through down-regulation of IGF-1 signaling pathway.
Maternal Betaine Supplementation throughout Gestation and Lactation Modifies Hepatic Cholesterol Metabolic Genes in Weaning Piglets via AMPK/LXR-Mediated Pathway and Histone Modification.
Downregulation of miR-150 Expression by DNA Hypermethylation Is Associated with High 2-Hydroxy-(4-methylthio)butanoic Acid-Induced Hepatic Cholesterol Accumulation in Nursery Piglets.
Dietary betaine supplementation to gestational sows enhances hippocampal IGF2 expression in newborn piglets with modified DNA methylation of the differentially methylated regions.
Maternal Betaine Supplementation during Gestation Enhances Expression of mtDNA-Encoded Genes through D-Loop DNA Hypomethylation in the Skeletal Muscle of Newborn Piglets.
Betaine supplementation in maternal diet modulates the epigenetic regulation of hepatic gluconeogenic genes in neonatal piglets.
Acosta CH, Clemons GA, Citadin CT, Carr WC, Udo MSB, Tesic V, Sanicola HW, Freelin AH, Toms JB, Jordan JD, Guthikonda B, Wu CY, Lee RH, Lin HW
Neurochemistry international 2023 Jun;166:105524
Neurochemistry international 2023 Jun;166:105524
Progesterone and interferon tau regulate expression of polyamine enzymes during the ovine peri-implantation period†.
Halloran KM, Stenhouse C, Moses RM, Seo H, Johnson GA, Wu G, Bazer FW
Biology of reproduction 2022 May 17;106(5):865-878
Biology of reproduction 2022 May 17;106(5):865-878
Mutant CHCHD10 causes an extensive metabolic rewiring that precedes OXPHOS dysfunction in a murine model of mitochondrial cardiomyopathy.
Sayles NM, Southwell N, McAvoy K, Kim K, Pesini A, Anderson CJ, Quinzii C, Cloonan S, Kawamata H, Manfredi G
Cell reports 2022 Mar 8;38(10):110475
Cell reports 2022 Mar 8;38(10):110475
mTORC1 stimulates cell growth through SAM synthesis and m(6)A mRNA-dependent control of protein synthesis.
Villa E, Sahu U, O'Hara BP, Ali ES, Helmin KA, Asara JM, Gao P, Singer BD, Ben-Sahra I
Molecular cell 2021 May 20;81(10):2076-2093.e9
Molecular cell 2021 May 20;81(10):2076-2093.e9
Grandmaternal betaine supplementation enhances hepatic IGF2 expression in F2 rat offspring through modification of promoter DNA methylation.
Yang S, Zhao N, Sun B, Yang Y, Hu Y, Zhao R
Journal of the science of food and agriculture 2020 Mar 15;100(4):1486-1494
Journal of the science of food and agriculture 2020 Mar 15;100(4):1486-1494
Dietary betaine improves egg-laying rate in hens through hypomethylation and glucocorticoid receptor-mediated activation of hepatic lipogenesis-related genes.
Omer NA, Hu Y, Idriss AA, Abobaker H, Hou Z, Yang S, Ma W, Zhao R
Poultry science 2020 Jun;99(6):3121-3132
Poultry science 2020 Jun;99(6):3121-3132
Maternal betaine supplementation decreases hepatic cholesterol deposition in chicken offspring with epigenetic modulation of SREBP2 and CYP7A1 genes.
Hu Y, Feng Y, Ding Z, Lv L, Sui Y, Sun Q, Abobaker H, Cai D, Zhao R
Poultry science 2020 Jun;99(6):3111-3120
Poultry science 2020 Jun;99(6):3111-3120
Mitotically Stable Modification of DNA Methylation in IGF2/H19 Imprinting Control Region Is Associated with Activated Hepatic IGF2 Expression in Offspring Rats from Betaine-Supplemented Dams.
Yang S, Zhao N, Yang Y, Hu Y, Dong H, Zhao R
Journal of agricultural and food chemistry 2018 Mar 21;66(11):2704-2713
Journal of agricultural and food chemistry 2018 Mar 21;66(11):2704-2713
Corticosterone-Induced Lipogenesis Activation and Lipophagy Inhibition in Chicken Liver Are Alleviated by Maternal Betaine Supplementation.
Hu Y, Sun Q, Hu Y, Hou Z, Zong Y, Omer NA, Abobaker H, Zhao R
The Journal of nutrition 2018 Mar 1;148(3):316-325
The Journal of nutrition 2018 Mar 1;148(3):316-325
Maternal betaine supplementation attenuates glucocorticoid-induced hepatic lipid accumulation through epigenetic modification in adult offspring rats.
Zhao N, Yang S, Jia Y, Sun B, He B, Zhao R
The Journal of nutritional biochemistry 2018 Apr;54:105-112
The Journal of nutritional biochemistry 2018 Apr;54:105-112
Maternal betaine administration modulates hepatic type 1 iodothyronine deiodinase (Dio1) expression in chicken offspring through epigenetic modifications.
Hou Z, Sun Q, Hu Y, Yang S, Zong Y, Zhao R
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 2018 Apr;218:30-36
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 2018 Apr;218:30-36
Metabolic adaptation of short-living growth hormone transgenic mice to methionine restriction and supplementation.
Brown-Borg HM, Rakoczy S, Wonderlich JA, Borg KE, Rojanathammanee L
Annals of the New York Academy of Sciences 2018 Apr;1418(1):118-136
Annals of the New York Academy of Sciences 2018 Apr;1418(1):118-136
Ligustrazine modulates renal cysteine biosynthesis in rats exposed to cadmium.
Kuang W, Zhang X, Zhu W, Lan Z
Environmental toxicology and pharmacology 2017 Sep;54:125-132
Environmental toxicology and pharmacology 2017 Sep;54:125-132
Prenatal betaine exposure modulates hypothalamic expression of cholesterol metabolic genes in cockerels through modifications of DNA methylation.
Idriss AA, Hu Y, Sun Q, Jia L, Jia Y, Omer NA, Abobaker H, Zhao R
Poultry science 2017 Jun 1;96(6):1715-1724
Poultry science 2017 Jun 1;96(6):1715-1724
In ovo injection of betaine alleviates corticosterone-induced fatty liver in chickens through epigenetic modifications.
Hu Y, Sun Q, Liu J, Jia Y, Cai D, Idriss AA, Omer NA, Zhao R
Scientific reports 2017 Jan 6;7:40251
Scientific reports 2017 Jan 6;7:40251
Folate deprivation induces cell cycle arrest at G0/G1 phase and apoptosis in hippocampal neuron cells through down-regulation of IGF-1 signaling pathway.
Yang Y, Li X, Sun Q, He B, Jia Y, Cai D, Zhao R
The international journal of biochemistry & cell biology 2016 Oct;79:222-230
The international journal of biochemistry & cell biology 2016 Oct;79:222-230
Maternal Betaine Supplementation throughout Gestation and Lactation Modifies Hepatic Cholesterol Metabolic Genes in Weaning Piglets via AMPK/LXR-Mediated Pathway and Histone Modification.
Cai D, Yuan M, Liu H, Pan S, Ma W, Hong J, Zhao R
Nutrients 2016 Oct 18;8(10)
Nutrients 2016 Oct 18;8(10)
Downregulation of miR-150 Expression by DNA Hypermethylation Is Associated with High 2-Hydroxy-(4-methylthio)butanoic Acid-Induced Hepatic Cholesterol Accumulation in Nursery Piglets.
Jia Y, Ling M, Zhang L, Jiang S, Sha Y, Zhao R
Journal of agricultural and food chemistry 2016 Oct 12;64(40):7530-7539
Journal of agricultural and food chemistry 2016 Oct 12;64(40):7530-7539
Dietary betaine supplementation to gestational sows enhances hippocampal IGF2 expression in newborn piglets with modified DNA methylation of the differentially methylated regions.
Li X, Sun Q, Li X, Cai D, Sui S, Jia Y, Song H, Zhao R
European journal of nutrition 2015 Oct;54(7):1201-10
European journal of nutrition 2015 Oct;54(7):1201-10
Maternal Betaine Supplementation during Gestation Enhances Expression of mtDNA-Encoded Genes through D-Loop DNA Hypomethylation in the Skeletal Muscle of Newborn Piglets.
Jia Y, Song H, Gao G, Cai D, Yang X, Zhao R
Journal of agricultural and food chemistry 2015 Nov 25;63(46):10152-60
Journal of agricultural and food chemistry 2015 Nov 25;63(46):10152-60
Betaine supplementation in maternal diet modulates the epigenetic regulation of hepatic gluconeogenic genes in neonatal piglets.
Cai D, Jia Y, Song H, Sui S, Lu J, Jiang Z, Zhao R
PloS one 2014;9(8):e105504
PloS one 2014;9(8):e105504
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HepG2 cells were subjected to SDS PAGE followed by western blot with 15952-1-AP(MAT2B antibody) at dilution of 1:800
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of HepG2 cells, using MAT2B antibody 15952-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human lung using 15952-1-AP(MAT2B antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human lung using 15952-1-AP(MAT2B antibody) at dilution of 1:100 (under 40x lens)
- Sample type
- tissue
