Antibody data
- Antibody Data
- Antigen structure
- References [52]
- Comments [0]
- Validations [0]
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- Product number
- 22601-1-AP - Provider product page

- Provider
- Proteintech Group
- Product name
- VEGFC antibody
- Antibody type
- Polyclonal
- Description
- VEGFC antibody (Cat. #22601-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IF, IHC, WB,ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Sparcl1 mitigates abdominal aortic aneurysm through inhibiting lymphangiogenesis-mediated TLS formation.
Huiyang Shengji Unguent Promotes Lymphangiogenesis and Wound Healing in Diabetic Chronic Wounds: Combined Insights from Proteomics and in vivo and in vitro Analyses.
Cyclic Heptapeptide FZ1 Acts as an Integrin αvβ3 Agonist to Facilitate Diabetic Skin Wound Healing by Enhancing Angiogenesis.
Single-Cell RNA Sequencing Reveals the Heterogeneity in Differentiation Trajectory and Tumor Microenvironment Leading to More Aggressive Phenotypes of Papillary Thyroid Cancer in Children and Young Adult Patients.
Hsa_circ_0005325 Regulates the Proliferation, Apoptosis, Colony Formation, Migration, and Angiogenesis-Promoting Behavior of Oral Squamous Cell Carcinoma Cells Through the miR-433-3p/HMGA2 Axis.
The RNA-Binding Proteins MCPIP2 and IGF2BP1 Competitively Modulate Breast Tumor Angiogenesis by Antagonizing VEGFA mRNA Stability and Expression.
Single-cell multi-stage spatial evolutional map of esophageal carcinogenesis.
Network pharmacology and bioinformatics analysis reveals: NXC improves cardiac lymphangiogenesis through miR-126-3p/SPRED1 regulating the VEGF-C axis to ameliorate post-myocardial infarction heart failure.
IL-19 Is a Novel Lymphangiocrine Factor Inducing Lymphangiogenesis and Lymphatic Junctional Regulation.
Tight orchestration of wound healing phase through metal-organic compounds.
SIX1 aggravates the progression of spinal cord injury in mice by promoting M1 polarization of microglia.
FN1 shapes the behavior of papillary thyroid carcinoma through alternative splicing of EDB region.
Single-nuclear transcriptomics of lymphedema-associated adipose reveals a pro-lymphangiogenic stromal cell population.
Mesangial angiogenesis and interstitial eosinophilic infiltration in diabetic nephropathy are associated with elevated CD248 expression.
Identification and validation of a novel lymph node metastasis-related model for papillary thyroid carcinoma to predict the prognosis.
Phenotype remodelling of HNSCC cells in the muscle invasion environment.
Distinct activation of M1 and M2 macrophages in the primary pterygium lymphangiogenesis.
Integrating single-cell and spatial analysis reveals MUC1-mediated cellular crosstalk in mucinous colorectal adenocarcinoma.
A new lymphedema treatment using pyro-drive jet injection.
A novel Senescence-Based prognostic model unveils tumor interactions and drug resistance in colorectal cancer.
An arabinogalactan isolated from Cynanchum atratum promotes lymphangiogenesis and lymphatic vessel remodeling to alleviate secondary lymphedema.
Berberine promotes lacteal junction zippering and ameliorates diet-induced obesity through the RhoA/ROCK signaling pathway.
Rosuvastatin Enhances Lymphangiogenesis after Myocardial Infarction by Regulating the miRNAs/Vascular Endothelial Growth Factor Receptor 3 (miRNAs/VEGFR3) Pathway.
Homology and the evolution of vocal folds in the novel avian voice box.
Macrophage-derived VEGF-C reduces cardiac inflammation and prevents heart dysfunction in CVB3-induced viral myocarditis via remodeling cardiac lymphatic vessels.
PIEZO2 promotes cell proliferation and metastasis in colon carcinoma through the SLIT2/ROBO1/VEGFC pathway.
SALL4 promotes angiogenesis in gastric cancer by regulating VEGF expression and targeting SALL4/VEGF pathway inhibits cancer progression.
WTAP promotes macrophage recruitment and increases VEGF secretion via N6-methyladenosine modification in corneal neovascularization.
HOXA11 promotes lymphatic metastasis of gastric cancer via transcriptional activation of TGFβ1.
Development of a method to identify persistent and blanchable redness by skin blotting in mice.
Angiotensin II Induces Cardiac Edema and Hypertrophic Remodeling through Lymphatic-Dependent Mechanisms.
Fenofibrate suppresses corneal neovascularization by regulating lipid metabolism through PPARα signaling pathway.
The Specifically Androgen-Regulated Gene (SARG) Promotes Papillary Thyroid Carcinoma (PTC) Lymphatic Metastasis Through Vascular Endothelial Growth Factor C (VEGF-C) and VEGF Receptor 3 (VEGFR-3) Axis.
ROS attenuates TET2-dependent ZO-1 epigenetic expression in cerebral vascular endothelial cells.
Effects of plant-based medicinal food on postoperative recurrence and lung metastasis of gastric cancer regulated by Wnt/β-catenin-EMT signaling pathway and VEGF-C/D-VEGFR-3 cascade in a mouse model.
Babao Dan inhibits lymphangiogenesis of gastric cancer in vitro and in vivo via lncRNA-ANRIL/VEGF-C/VEGFR-3 signaling axis.
Clostridium butyricum alleviates dextran sulfate sodium-induced experimental colitis and promotes intestinal lymphatic vessel regeneration in mice.
BANCR positively regulates the HIF-1α/VEGF-C/VEGFR-3 pathway in a hypoxic microenvironment to promote lymphangiogenesis in pancreatic cancer cells.
Human Placental Endothelial Cell and Trophoblast Heterogeneity and Differentiation Revealed by Single-Cell RNA Sequencing.
Neurturin promotes tumor cell motility and angiogenesis in colorectal cancer.
Development and Validation of a Nomogram based on cell growth-related Biomarkers for Oral Squamous Cell Carcinoma.
Immunoreactivity and a new staining method of monocarboxylate transporter 1 located in endothelial cells of cerebral vessels of human brain in distinguishing cerebral venules from arterioles.
VEGF-C/VEGFR-3 axis protects against pressure-overload induced cardiac dysfunction through regulation of lymphangiogenesis.
The Hippo-TAZ axis mediates vascular endothelial growth factor C in glioblastoma-derived exosomes to promote angiogenesis.
Wnt Signaling Regulates the Lymphatic Endothelial Transdifferentiation of Adipose-Derived Stromal Cells In Vitro.
DUSP2 regulates extracellular vesicle-VEGF-C secretion and pancreatic cancer early dissemination.
Transcriptional Downregulation of miR-4306 serves as a New Therapeutic Target for Triple Negative Breast Cancer.
MicroRNA-330-3p promotes brain metastasis and epithelial-mesenchymal transition via GRIA3 in non-small cell lung cancer.
Induced Expression of VEGFC, ANGPT, and EFNB2 and Their Receptors Characterizes Neovascularization in Proliferative Diabetic Retinopathy.
Epigenetically upregulated oncoprotein PLCE1 drives esophageal carcinoma angiogenesis and proliferation via activating the PI-PLCε-NF-κB signaling pathway and VEGF-C/ Bcl-2 expression.
Macrophages Regulate Unilateral Ureteral Obstruction-Induced Renal Lymphangiogenesis through C-C Motif Chemokine Receptor 2-Dependent Phosphatidylinositol 3-Kinase-AKT-Mechanistic Target of Rapamycin Signaling and Hypoxia-Inducible Factor-1α/Vascular Endothelial Growth Factor-C Expression.
ZEB1 Upregulates VEGF Expression and Stimulates Angiogenesis in Breast Cancer.
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Nature immunology 2026 Apr;27(4):738-749
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SIX1 aggravates the progression of spinal cord injury in mice by promoting M1 polarization of microglia.
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Single-nuclear transcriptomics of lymphedema-associated adipose reveals a pro-lymphangiogenic stromal cell population.
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Berberine promotes lacteal junction zippering and ameliorates diet-induced obesity through the RhoA/ROCK signaling pathway.
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Macrophage-derived VEGF-C reduces cardiac inflammation and prevents heart dysfunction in CVB3-induced viral myocarditis via remodeling cardiac lymphatic vessels.
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PIEZO2 promotes cell proliferation and metastasis in colon carcinoma through the SLIT2/ROBO1/VEGFC pathway.
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SALL4 promotes angiogenesis in gastric cancer by regulating VEGF expression and targeting SALL4/VEGF pathway inhibits cancer progression.
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WTAP promotes macrophage recruitment and increases VEGF secretion via N6-methyladenosine modification in corneal neovascularization.
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International wound journal 2023 Apr;20(4):1168-1182
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Fenofibrate suppresses corneal neovascularization by regulating lipid metabolism through PPARα signaling pathway.
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Frontiers in pharmacology 2022;13:1000254
Frontiers in pharmacology 2022;13:1000254
The Specifically Androgen-Regulated Gene (SARG) Promotes Papillary Thyroid Carcinoma (PTC) Lymphatic Metastasis Through Vascular Endothelial Growth Factor C (VEGF-C) and VEGF Receptor 3 (VEGFR-3) Axis.
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Frontiers in oncology 2022;12:817660
ROS attenuates TET2-dependent ZO-1 epigenetic expression in cerebral vascular endothelial cells.
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Fluids and barriers of the CNS 2022 Sep 8;19(1):73
Effects of plant-based medicinal food on postoperative recurrence and lung metastasis of gastric cancer regulated by Wnt/β-catenin-EMT signaling pathway and VEGF-C/D-VEGFR-3 cascade in a mouse model.
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BMC complementary medicine and therapies 2022 Sep 2;22(1):233
Babao Dan inhibits lymphangiogenesis of gastric cancer in vitro and in vivo via lncRNA-ANRIL/VEGF-C/VEGFR-3 signaling axis.
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Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2022 Oct;154:113630
Clostridium butyricum alleviates dextran sulfate sodium-induced experimental colitis and promotes intestinal lymphatic vessel regeneration in mice.
Chen X, Ma L, Liu X, Wang J, Li Y, Xie Q, Liang J
Annals of translational medicine 2022 Mar;10(6):341
Annals of translational medicine 2022 Mar;10(6):341
BANCR positively regulates the HIF-1α/VEGF-C/VEGFR-3 pathway in a hypoxic microenvironment to promote lymphangiogenesis in pancreatic cancer cells.
Hao S, Han W, Ji Y, Sun H, Shi H, Ma J, Yip J, Ding Y
Oncology letters 2022 Dec;24(6):422
Oncology letters 2022 Dec;24(6):422
Human Placental Endothelial Cell and Trophoblast Heterogeneity and Differentiation Revealed by Single-Cell RNA Sequencing.
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Cells 2022 Dec 25;12(1)
Cells 2022 Dec 25;12(1)
Neurturin promotes tumor cell motility and angiogenesis in colorectal cancer.
Wang S, Nie L, Song Y, Zhang F, Chen X, Shi W, Yang Z, Sun Y, Dang Q, Gao A
Experimental cell research 2022 Apr 1;413(1):113049
Experimental cell research 2022 Apr 1;413(1):113049
Development and Validation of a Nomogram based on cell growth-related Biomarkers for Oral Squamous Cell Carcinoma.
Shuai Y, Duan Y, Zhou M, Yue K, Liu D, Fang Y, Wang Y, Wu Y, Zhang Z, Wang X
Journal of Cancer 2021;12(17):5153-5163
Journal of Cancer 2021;12(17):5153-5163
Immunoreactivity and a new staining method of monocarboxylate transporter 1 located in endothelial cells of cerebral vessels of human brain in distinguishing cerebral venules from arterioles.
Cao Y, Ao DH, Ma C, Qiu WY, Zhu YC
European journal of histochemistry : EJH 2021 Oct 1;65(s1)
European journal of histochemistry : EJH 2021 Oct 1;65(s1)
VEGF-C/VEGFR-3 axis protects against pressure-overload induced cardiac dysfunction through regulation of lymphangiogenesis.
Lin QY, Zhang YL, Bai J, Liu JQ, Li HH
Clinical and translational medicine 2021 Mar;11(3):e374
Clinical and translational medicine 2021 Mar;11(3):e374
The Hippo-TAZ axis mediates vascular endothelial growth factor C in glioblastoma-derived exosomes to promote angiogenesis.
Wang Z, Yuan Y, Ji X, Xiao X, Li Z, Yi X, Zhu Y, Guo T, Wang Y, Chen L, Liu Y
Cancer letters 2021 Aug 10;513:1-13
Cancer letters 2021 Aug 10;513:1-13
Wnt Signaling Regulates the Lymphatic Endothelial Transdifferentiation of Adipose-Derived Stromal Cells In Vitro.
Zhang N, Hu L, Liu J, Yang W, Li Y, Pan J
Cellular reprogramming 2021 Apr;23(2):117-126
Cellular reprogramming 2021 Apr;23(2):117-126
DUSP2 regulates extracellular vesicle-VEGF-C secretion and pancreatic cancer early dissemination.
Wang CA, Chang IH, Hou PC, Tai YJ, Li WN, Hsu PL, Wu SR, Chiu WT, Li CF, Shan YS, Tsai SJ
Journal of extracellular vesicles 2020;9(1):1746529
Journal of extracellular vesicles 2020;9(1):1746529
Transcriptional Downregulation of miR-4306 serves as a New Therapeutic Target for Triple Negative Breast Cancer.
Zhao Z, Li L, Du P, Ma L, Zhang W, Zheng L, Lan B, Zhang B, Ma F, Xu B, Zhan Q, Song Y
Theranostics 2019;9(5):1401-1416
Theranostics 2019;9(5):1401-1416
MicroRNA-330-3p promotes brain metastasis and epithelial-mesenchymal transition via GRIA3 in non-small cell lung cancer.
Wei C, Zhang R, Cai Q, Gao X, Tong F, Dong J, Hu Y, Wu G, Dong X
Aging 2019 Sep 8;11(17):6734-6761
Aging 2019 Sep 8;11(17):6734-6761
Induced Expression of VEGFC, ANGPT, and EFNB2 and Their Receptors Characterizes Neovascularization in Proliferative Diabetic Retinopathy.
Li Y, Chen D, Sun L, Wu Y, Zou Y, Liang C, Bao Y, Yi J, Zhang Y, Hou J, Li Z, Yu F, Huang Y, Yu C, Liu L, Liu Z, Zhang Y, Li Y
Investigative ophthalmology & visual science 2019 Oct 1;60(13):4084-4096
Investigative ophthalmology & visual science 2019 Oct 1;60(13):4084-4096
Epigenetically upregulated oncoprotein PLCE1 drives esophageal carcinoma angiogenesis and proliferation via activating the PI-PLCε-NF-κB signaling pathway and VEGF-C/ Bcl-2 expression.
Chen Y, Wang D, Peng H, Chen X, Han X, Yu J, Wang W, Liang L, Liu Z, Zheng Y, Hu J, Yang L, Li J, Zhou H, Cui X, Li F
Molecular cancer 2019 Jan 4;18(1):1
Molecular cancer 2019 Jan 4;18(1):1
Macrophages Regulate Unilateral Ureteral Obstruction-Induced Renal Lymphangiogenesis through C-C Motif Chemokine Receptor 2-Dependent Phosphatidylinositol 3-Kinase-AKT-Mechanistic Target of Rapamycin Signaling and Hypoxia-Inducible Factor-1α/Vascular Endothelial Growth Factor-C Expression.
Guo YC, Zhang M, Wang FX, Pei GC, Sun F, Zhang Y, He X, Wang Y, Song J, Zhu FM, Pandupuspitasari NS, Liu J, Huang K, Yang P, Xiong F, Zhang S, Yu Q, Yao Y, Wang CY
The American journal of pathology 2017 Aug;187(8):1736-1749
The American journal of pathology 2017 Aug;187(8):1736-1749
ZEB1 Upregulates VEGF Expression and Stimulates Angiogenesis in Breast Cancer.
Liu L, Tong Q, Liu S, Cui J, Zhang Q, Sun W, Yang S
PloS one 2016;11(2):e0148774
PloS one 2016;11(2):e0148774
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