Antibody data
- Antibody Data
- Antigen structure
- References [9]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- 10393-1-AP - Provider product page

- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10393-1-AP, RRID:AB_2083555
- Product name
- COMMD5 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated COMMD5 antibody (Cat. #10393-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IF, IP, WB,ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Inhibition of lipopolysaccharide-induced inflammation by trophoblast-conditioned medium and trophoblast-derived extracellular vesicles in human middle ear epithelial cells.
Celastrol suppresses humoral immune responses and autoimmunity by targeting the COMMD3/8 complex.
Genome-wide CRISPR screen identified a role for commander complex mediated ITGB1 recycling in basal insulin secretion.
Lipid kinases VPS34 and PIKfyve coordinate a phosphoinositide cascade to regulate retriever-mediated recycling on endosomes.
COMMD5 Inhibits Malignant Behavior of Renal Cancer Cells.
COMMD5/HCaRG Hooks Endosomes on Cytoskeleton and Coordinates EGFR Trafficking.
HCaRG/COMMD5 inhibits ErbB receptor-driven renal cell carcinoma.
HCaRG accelerates tubular repair after ischemic kidney injury.
Rosiglitazone suppresses gastric carcinogenesis by up-regulating HCaRG expression.
Lee CM, Go YY, Song JJ
Scientific reports 2023 Nov 14;13(1):19822
Scientific reports 2023 Nov 14;13(1):19822
Celastrol suppresses humoral immune responses and autoimmunity by targeting the COMMD3/8 complex.
Shirai T, Nakai A, Ando E, Fujimoto J, Leach S, Arimori T, Higo D, van Eerden FJ, Tulyeu J, Liu YC, Okuzaki D, Murayama MA, Miyata H, Nunomura K, Lin B, Tani A, Kumanogoh A, Ikawa M, Wing JB, Standley DM, Takagi J, Suzuki K
Science immunology 2023 Mar 31;8(81):eadc9324
Science immunology 2023 Mar 31;8(81):eadc9324
Genome-wide CRISPR screen identified a role for commander complex mediated ITGB1 recycling in basal insulin secretion.
Yang L, Fye MA, Yang B, Tang Z, Zhang Y, Haigh S, Covington BA, Bracey K, Taraska JW, Kaverina I, Qu S, Chen W
Molecular metabolism 2022 Sep;63:101541
Molecular metabolism 2022 Sep;63:101541
Lipid kinases VPS34 and PIKfyve coordinate a phosphoinositide cascade to regulate retriever-mediated recycling on endosomes.
Giridharan SSP, Luo G, Rivero-Rios P, Steinfeld N, Tronchere H, Singla A, Burstein E, Billadeau DD, Sutton MA, Weisman LS
eLife 2022 Jan 18;11
eLife 2022 Jan 18;11
COMMD5 Inhibits Malignant Behavior of Renal Cancer Cells.
Ikeda J, Matsuda H, Ogasawara M, Ishii Y, Yamaguchi K, Takahashi S, Fukuda N, Masuhiro Y, Endo M, Soma M, Hamet P, Tremblay J
Anticancer research 2021 Jun;41(6):2805-2815
Anticancer research 2021 Jun;41(6):2805-2815
COMMD5/HCaRG Hooks Endosomes on Cytoskeleton and Coordinates EGFR Trafficking.
Campion CG, Zaoui K, Verissimo T, Cossette S, Matsuda H, Solban N, Hamet P, Tremblay J
Cell reports 2018 Jul 17;24(3):670-684.e7
Cell reports 2018 Jul 17;24(3):670-684.e7
HCaRG/COMMD5 inhibits ErbB receptor-driven renal cell carcinoma.
Matsuda H, Campion CG, Fujiwara K, Ikeda J, Cossette S, Verissimo T, Ogasawara M, Gaboury L, Saito K, Yamaguchi K, Takahashi S, Endo M, Fukuda N, Soma M, Hamet P, Tremblay J
Oncotarget 2017 Sep 19;8(41):69559-69576
Oncotarget 2017 Sep 19;8(41):69559-69576
HCaRG accelerates tubular repair after ischemic kidney injury.
Matsuda H, Lavoie JL, Gaboury L, Hamet P, Tremblay J
Journal of the American Society of Nephrology : JASN 2011 Nov;22(11):2077-89
Journal of the American Society of Nephrology : JASN 2011 Nov;22(11):2077-89
Rosiglitazone suppresses gastric carcinogenesis by up-regulating HCaRG expression.
Chen BL, Yu J, Zeng ZR, Chu WK, Wong CY, Cheng YY, Sung JJ, Hu PJ, Leung WK
Oncology reports 2008 Nov;20(5):1093-7
Oncology reports 2008 Nov;20(5):1093-7
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Supportive validation
- Submitted by
- Proteintech Group (provider)
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- Experimental details
- The COMMD5 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human COMMD5. This antibody recognizes human, mouse, rat antigen. The COMMD5 antibody has been validated for the following applications: ELISA, WB analysis.