Antibody data
- Antibody Data
- Antigen structure
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- Validations
- Western blot [1]
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- Product number
- BS8151 - Provider product page
- Provider
- Bioworld Technology, Inc
- Product name
- AGA polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- Recombinant full length Human AGA.
- Description
- AGA (aspartylglucosaminidase) is a 346 amino acid precursor protein that belongs to the Ntn-hydrolase family and is cleaved to produce an Ï« chain and a ÉÇ chain. Localized to the lysosome, AGA functions as a heterotetramer composed of two Ï« and two ÉÇ chains that work together to cleave the GlcNAc-Asn bond that joins oligosaccharides to target glycoproteins. Defects in the gene encoding AGA are the cause of aspartylglucosaminuria (AGU), a lysosomal storage disease that is characterized by severe mental retardation and mild connective tissue abnormalities. The gene encoding AGA maps to human chromosome 4, which encodes nearly 6% of the human genome and has the largest gene deserts (regions of the genome with no protein encoding genes) of all of the human chromosomes.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100ul
- Concentration
- 1 mg/ml
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
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Supportive validation
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- Bioworld Technology, Inc (provider)
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- Experimental details
- WesternBlot (WB) analysis of AGA polyclonal antibody