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- Antigen structure
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- Product number
- 22170-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#22170-1-AP, RRID:AB_2713959
- Product name
- CPT1B-specific antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated CPT1B-specific antibody (Cat. #22170-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references A promising magnesium-related alloy with metabolic reprogramming and antitumor effects in hepatocellular and pancreatic cancer.
Acox1 induces lipid peroxidation and metabolic shifting to promote PASMCs proliferation in hypoxia-induced pulmonary hypertension.
Disturbed mitochondrial maturation in cardiolipin remodeling-deficient cardiomyocytes.
Transplantation of Soluble Epoxide Hydrolase Inhibitor-Treated Human Brown Adipocytes Promotes Adipose Tissue Activation in High-Fat-Diet-Fed Nude Mice.
Lingguizhugan decoction improves cognitive impairment in APP/PS1 mice by promoting meningeal lymphatic drainage based on fatty acid degradation pathway.
Annexin A1 exacerbates islet stellate cell activation by regulating triglyceride catabolism via the PPARα/ACOX1/CYP4a pathway.
Huodan Qinghua formula inhibits CD36 membrane localisation via the TGR5-DHHC4 pathway to ameliorate lipotoxic damage in diabetic cardiomyopathy.
Fiber type-specific expression of LACTB leverages a function in oxidative metabolism.
α-Mangostin prevents diabetic cardiomyopathy by inhibiting oxidative damage and lipotoxicity through the AKT-FOXO1-CD36 pathway.
Circular RNA CHACR is involved in the pathogenesis of cardiac hypertrophy.
Mitochondrial fatty acid oxidation dysfunction impairs autophagic flux through ATP deficiency-caused lysosomal pH abnormity.
Endogenous synthesis of n-3 PUFAs can reduce lipid synthesis in Fad3 transgenic cattle.
Mechanism by which CAP regulates the "cold-heat" balance in osteosarcoma model mice: an integrative study of metabolomics, transcriptomics, and network pharmacology.
Gut symbiont-derived ursodeoxycholic acid promotes fatty acid oxidation to protect against renal ischemia-reperfusion injury.
Co-administration of berberine and evodiamine: Mitigating evodiamine-induced hepatotoxicity and potentiating colitis treatment.
Inhalation of Ultrafine Carbon Black-Induced Mitochondrial Dysfunction in Mouse Heart Through Changes in Acetylation.
Dietary combination of sucrose and linoleic acid increases intramyocellular lipid and impairs muscle strength in female Zucker diabetic fatty rats.
The inhibition of PPARα protein degradation alleviates the cardiotoxicity of Tiebangchui by regulating fatty acid metabolism.
A cold-inducible phospholipid-protein interaction in brown fat mitochondria optimizes thermogenic capacity.
Integrative analysis of genes provides insights into the molecular and immune characteristics of mitochondria-related genes in atherosclerosis.
Etomoxir suppresses the expression of PPARγ2 and inhibits the thermogenic gene induction of brown adipocytes through pathways other than β-oxidation inhibition.
Inhibition of serotonin-Htr2b signaling in skeletal muscle mitigates obesity-induced insulin resistance.
Early-life exercise extends healthspan but not lifespan in mice.
The role of quercetin in modulating lipid metabolism and enhancing chemotherapy via the STAT3-CPT1B pathway in pancreatic cancer.
Qifu Decoction Alleviates Lipopolysaccharide-Induced Myocardial Dysfunction by Inhibiting TLR4/NF-κB/NLRP3 Inflammatory Pathway and Activating PPARα/CPT Pathway.
Reversing metabolic reprogramming by CPT1 inhibition with etomoxir promotes cardiomyocyte proliferation and heart regeneration via DUSP1 ADP-ribosylation-mediated p38 MAPK phosphorylation.
Sex Differences in Response to Diet Enriched With Glutathione Precursors in the Aging Heart.
Moderate-intensity interval exercise exacerbates cardiac lipotoxicity in high-fat, high-calories diet-fed mice.
Trans 10, cis 12-conjugated linoleic acid in low concentration reduces while in high concentration enhances adipocyte metabolism but effectively improves hepatic steatosis of obese mice.
FGF21 protects against HFpEF by improving cardiac mitochondrial bioenergetics in mice.
BMP10 attenuates age-related atrial fibrillation susceptibility through improving mitochondrial function in atrial cardiomyocytes.
(-)-Guaiol Downregulates M2 Tumor-Associated Macrophage Polarization Through PPAR-γ Signaling to Suppress Lung Cancer.
Gallic Acid Ameliorates Skeletal Muscle Metabolic Inflexibility by Regulating Lactate Metabolism and Promoting Mitochondrial Function.
Ankyrin-B modulates mitochondrial fission in skeletal muscle and is required for optimal endurance exercise capacity.
The TEX44-CPT1B axis regulates mitochondrial sheath assembly and fatty acid oxidation in sperm.
2-Methoxyestradiol ameliorates doxorubicin-induced cardiotoxicity by regulating the expression of GLUT4 and CPT-1B in female rats.
S-1-Propenylcysteine Enhances Endurance Capacity of Mice by Stimulating Fatty Acid Metabolism via Muscle Isoform of Carnitine Acyltransferase-1.
Etomoxir repurposed as a promiscuous fatty acid mimetic chemoproteomic probe.
Epicatechin and β-glucan from whole highland barley grain ameliorates hyperlipidemia associated with attenuating intestinal barrier dysfunction and modulating gut microbiota in high-fat-diet-fed mice.
Systemic inhibition of mitochondrial fatty acid β-oxidation impedes zebrafish ventricle regeneration.
Involvement of mitochondrial fatty acid β-oxidation in the antiviral innate immune response in head kidney macrophages of large yellow croaker (Larimichthys crocea).
The ZNF263/CPT1B axis regulates fatty acid β-oxidation to affect cisplatin resistance in lung adenocarcinoma.
Transgenic female mice producing trans 10, cis 12-conjugated linoleic acid present excessive prostaglandin E2, adrenaline, corticosterone, glucagon, and FGF21.
APC/C-regulated CPT1C promotes tumor progression by upregulating the energy supply and accelerating the G1/S transition.
Low phosphorus increases hepatic lipid deposition, oxidative stress and inflammatory response via Acetyl-CoA carboxylase-dependent manner in zebrafish liver cells.
Cardiomyocyte-specific deletion of GCN5L1 reduces lysine acetylation and attenuates diastolic dysfunction in aged mice by improving cardiac fatty acid oxidation.
Procyanidin B1 and Coumaric Acid from Highland Barley Alleviated High-Fat-Diet-Induced Hyperlipidemia by Regulating PPARα-Mediated Hepatic Lipid Metabolism and Gut Microbiota in Diabetic C57BL/6J Mice.
Adipocyte pyroptosis occurs in omental tumor microenvironment and is associated with chemoresistance of ovarian cancer.
Xinbao Pill ameliorates heart failure via regulating the SGLT1/AMPK/PPARα axis to improve myocardial fatty acid energy metabolism.
Circular RNA circMYLK4 shifts energy metabolism from glycolysis to OXPHOS by binding to the calcium channel auxiliary subunit CACNA2D2.
Acid Neutralization by Composite Lysine Nanoparticles for Spinal Cord Injury Recovery through Mitigating Mitochondrial Dysfunction.
MicroRNA-21 modulates brown adipose tissue adipogenesis and thermogenesis in a mouse model of polycystic ovary syndrome.
Dietary oleic acid intake increases the proportion of type 1 and 2X muscle fibers in mice.
Regulation of Na+-K+-ATPase leads to disturbances of isoproterenol-induced cardiac dysfunction via interference of Ca2+-dependent cardiac metabolism.
Tcap deficiency impedes striated muscle function and heart regeneration with elevated ROS and autophagy.
Leptin limits hepatic lipid accumulation and inflammation via vagal activation of the JAK2-STAT3/AMPK pathway.
Carnitine palmitoyltransferase 1 facilitates fatty acid oxidation in a non-cell-autonomous manner.
ANXA1-FPR2 axis mitigates the susceptibility to atrial fibrillation in obesity via rescuing AMPK activity in response to lipid overload.
Tip60-mediated Rheb acetylation links palmitic acid with mTORC1 activation and insulin resistance.
Defects in integrin complex formation promote CHKB-mediated muscular dystrophy.
Voluntary Wheel Running Reduces Cardiometabolic Risks in Female Offspring Exposed to Lifelong High-Fat, High-Sucrose Diet.
Alternating current electromagnetic field exposure lessens intramyocellular lipid accumulation due to high-fat feeding via enhanced lipid metabolism in mice.
Inhibition of fatty acid oxidation enables heart regeneration in adult mice.
Transgenic mice producing the trans 10, cis 12-conjugated linoleic acid present reduced adiposity and increased thermogenesis and fibroblast growth factor 21 (FGF21).
The Enhancement of Acylcarnitine Metabolism by 5-Heptadecylresorcinol in Brown Adipose Tissue Contributes to Improving Glucose and Lipid Levels in Aging Male Mice.
Transcriptome Analysis Revealed Potential Genes of Skeletal Muscle Thermogenesis in Mashen Pigs and Large White Pigs under Cold Stress.
Ginsenoside Rb1 promotes the activation of PPARα pathway via inhibiting FADD to ameliorate heart failure.
Myocardial brain-derived neurotrophic factor regulates cardiac bioenergetics through the transcription factor Yin Yang 1.
5-HEPE reduces obesity and insulin resistance by promoting adipose tissue browning through GPR119/AMPK/PGC1α activation.
Downregulation of extramitochondrial BCKDH and its uncoupling from AMP deaminase in type 2 diabetic OLETF rat hearts.
Fatty acid β-oxidation and mitochondrial fusion are involved in cardiac microvascular endothelial cell protection induced by glucagon receptor antagonism in diabetic mice.
m6A-Modified circTET2 Interacting with HNRNPC Regulates Fatty Acid Oxidation to Promote the Proliferation of Chronic Lymphocytic Leukemia.
High Concentrations of Nucleotides Prevent Capillary Regression during Hindlimb Unloading by Inhibiting Oxidative Stress and Enhancing Mitochondrial Metabolism of Soleus Muscles in Rats.
Maturation of lipid metabolism in the fetal and newborn sheep heart.
Distinct effects of cardiac mitochondrial calcium uniporter inactivation via EMRE deletion in the short and long term.
Puerarin Prevents Bisphenol S Induced Lipid Accumulation by Reducing Liver Lipid Synthesis and Promoting Lipid Metabolism in C57BL/6J Mice.
G-protein coupled receptor 19 (GPR19) knockout mice display sex-dependent metabolic dysfunction.
Maternal High-Fat Diet Impairs Placental Fatty Acid β-Oxidation and Metabolic Homeostasis in the Offspring.
MCC950, a Selective NLRP3 Inhibitor, Attenuates Adverse Cardiac Remodeling Following Heart Failure Through Improving the Cardiometabolic Dysfunction in Obese Mice.
LAMC1-mediated preadipocytes differentiation promoted peritoneum pre-metastatic niche formation and gastric cancer metastasis.
First comprehensive identification of cardiac proteins with putative increased O-GlcNAc levels during pressure overload hypertrophy.
Differing impact of phosphoglycerate mutase 1-deficiency on brown and white adipose tissue.
Mechanism of action and therapeutic route for a muscular dystrophy caused by a genetic defect in lipid metabolism.
Exercise promotes angiogenesis by enhancing endothelial cell fatty acid utilization via liver-derived extracellular vesicle miR-122-5p.
MicroRNA-377-3p inhibits hepatocellular carcinoma growth and metastasis through negative regulation of CPT1C-mediated fatty acid oxidation.
Intrauterine growth restriction elevates circulating acylcarnitines and suppresses fatty acid metabolism genes in the fetal sheep heart.
A mechanosensitive lipolytic factor in the bone marrow promotes osteogenesis and lymphopoiesis.
The Protective Effect of 1,25(OH)(2)D(3) on Myocardial Function is Mediated via Sirtuin 3-Regulated Fatty Acid Metabolism.
FABP3 Deficiency Exacerbates Metabolic Derangement in Cardiac Hypertrophy and Heart Failure via PPARα Pathway.
Enhancing Fatty Acids Oxidation via L-Carnitine Attenuates Obesity-Related Atrial Fibrillation and Structural Remodeling by Activating AMPK Signaling and Alleviating Cardiac Lipotoxicity.
Bawei Chenxiang Wan Ameliorates Cardiac Hypertrophy by Activating AMPK/PPAR-α Signaling Pathway Improving Energy Metabolism.
PHDs/CPT1B/VDAC1 axis regulates long-chain fatty acid oxidation in cardiomyocytes.
Exercise improves lipid metabolism disorders induced by high-fat diet in a SESN2/JNK-independent manner.
LEFTY-PITX2 signaling pathway is critical for generation of mature and ventricular cardiac organoids in human pluripotent stem cell-derived cardiac mesoderm cells.
Effects of Simvastatin on Lipid Metabolism in Wild-Type Mice and Mice with Muscle PGC-1α Overexpression.
Short-term but not long-term high fat diet feeding protects against pressure overload-induced heart failure through activation of mitophagy.
Combined effects of a ketogenic diet and exercise training alter mitochondrial and peroxisomal substrate oxidative capacity in skeletal muscle.
Differential Effects of 17,18-EEQ and 19,20-EDP Combined with Soluble Epoxide Hydrolase Inhibitor t-TUCB on Diet-Induced Obesity in Mice.
Nanoparticle-Mediated Lipid Metabolic Reprogramming of T Cells in Tumor Microenvironments for Immunometabolic Therapy.
Aging Influences the Metabolic and Inflammatory Phenotype in an Experimental Mouse Model of Acute Lung Injury.
Targeting CPT1B as a potential therapeutic strategy in castration-resistant and enzalutamide-resistant prostate cancer.
Peroxisomal proliferator-activated receptor α-b deficiency induces the reprogramming of nutrient metabolism in zebrafish.
LncRNAH19 improves insulin resistance in skeletal muscle by regulating heterogeneous nuclear ribonucleoprotein A1.
Modulation of Fatty Acid-Related Genes in the Response of H9c2 Cardiac Cells to Palmitate and n-3 Polyunsaturated Fatty Acids.
Cardiac-specific LRP6 knockout induces lipid accumulation through Drp1/CPT1b pathway in adult mice.
Novel metabolic disorders in skeletal muscle of Lipodystrophic Bscl2/Seipin deficient mice.
PGC-1α Participates in the Protective Effect of Chronic Intermittent Hypobaric Hypoxia on Cardiomyocytes.
Global Analysis of Plasma Lipids Identifies Liver-Derived Acylcarnitines as a Fuel Source for Brown Fat Thermogenesis.
TXNIP regulates myocardial fatty acid oxidation via miR-33a signaling.
Zhang J, Gu J, Xia R, Yin J, Wang X, Yang J, Wang Y, Yi Z, Wang S, Zhang Q, Wang H, She J, Guo S
Bioactive materials 2026 May;59:186-204
Bioactive materials 2026 May;59:186-204
Acox1 induces lipid peroxidation and metabolic shifting to promote PASMCs proliferation in hypoxia-induced pulmonary hypertension.
Liang Q, Wang Y, Zhang X, Guo D, Qu G, Sun N, Xu J, Niu X, Liu Y, Geng J, Luo H, Wang C, Xin M, Wang X, Li Y, Jin F, Hu L
Free radical biology & medicine 2026 May;248:469-484
Free radical biology & medicine 2026 May;248:469-484
Disturbed mitochondrial maturation in cardiolipin remodeling-deficient cardiomyocytes.
Senoo N, Sheridan MS, Wohlfarter Y, Primrose MT, Tampakakis E, Keller MA, Claypool SM
iScience 2026 Mar 20;29(3):115111
iScience 2026 Mar 20;29(3):115111
Transplantation of Soluble Epoxide Hydrolase Inhibitor-Treated Human Brown Adipocytes Promotes Adipose Tissue Activation in High-Fat-Diet-Fed Nude Mice.
Wu H, Xu X, Chen J, Morisseau C, Hammock BD, Tseng YH, Zhao L
International journal of molecular sciences 2026 Jan 31;27(3)
International journal of molecular sciences 2026 Jan 31;27(3)
Lingguizhugan decoction improves cognitive impairment in APP/PS1 mice by promoting meningeal lymphatic drainage based on fatty acid degradation pathway.
Shen Z, Wu M, Sun S, Ling Y, Chen X, Zhang J, Zhou X, Zhou C
Journal of ethnopharmacology 2026 Jan 30;355(Pt B):120748
Journal of ethnopharmacology 2026 Jan 30;355(Pt B):120748
Annexin A1 exacerbates islet stellate cell activation by regulating triglyceride catabolism via the PPARα/ACOX1/CYP4a pathway.
Li Q, Zhang Y, Yu T, Shi L, Qiu Q, Wang B, Sang Y, Li R, Lv Q, Wang J, Liu X, Geng H, Jones PM, Liang J, Xu W
Islets 2026 Dec 31;18(1):2633793
Islets 2026 Dec 31;18(1):2633793
Huodan Qinghua formula inhibits CD36 membrane localisation via the TGR5-DHHC4 pathway to ameliorate lipotoxic damage in diabetic cardiomyopathy.
Fan X, Ge J, Liang Y, Yan Z, Geng X, Li M, Sun X, Zhu B, Shang W, Jia Y, Zhao Y, Kang Y, Zhang Z, Hu Y, Zhang J
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Apr;153:157761
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 Apr;153:157761
Fiber type-specific expression of LACTB leverages a function in oxidative metabolism.
Alanen KM, Soliymani R, Sarparanta J, Kuure S, Sainio K, Polianskyte Z, Asghar MY, Zangene E, Cascone A, Lalowski M, Hackman P, Lundin J, Lindholm D, Eriksson O
Histochemistry and cell biology 2026 Apr 18;164(1)
Histochemistry and cell biology 2026 Apr 18;164(1)
α-Mangostin prevents diabetic cardiomyopathy by inhibiting oxidative damage and lipotoxicity through the AKT-FOXO1-CD36 pathway.
Bai X, Zhang Z, Zhang M, Xu J, Dong K, Du Q, Chen L, Ma P, Yang J
Frontiers in pharmacology 2025;16:1566311
Frontiers in pharmacology 2025;16:1566311
Circular RNA CHACR is involved in the pathogenesis of cardiac hypertrophy.
Chen L, Wang W, Zhao Y, Zhang S, Zhou X
Theranostics 2025;15(8):3627-3642
Theranostics 2025;15(8):3627-3642
Mitochondrial fatty acid oxidation dysfunction impairs autophagic flux through ATP deficiency-caused lysosomal pH abnormity.
Zhang YY, Lv ZD, Wang M, Wang JX, Limbu SM, Qiao F, Chen LQ, Zhang ML, Luo Y, Du ZY
The Journal of nutritional biochemistry 2025 Sep;143:109943
The Journal of nutritional biochemistry 2025 Sep;143:109943
Endogenous synthesis of n-3 PUFAs can reduce lipid synthesis in Fad3 transgenic cattle.
Li D, Gao Y, Zhao X, Yun Y, Bo C, Song L, Yang L, Bai C, Li G, Su G
Biochimica et biophysica acta. Molecular and cell biology of lipids 2025 Oct;1870(7):159672
Biochimica et biophysica acta. Molecular and cell biology of lipids 2025 Oct;1870(7):159672
Mechanism by which CAP regulates the "cold-heat" balance in osteosarcoma model mice: an integrative study of metabolomics, transcriptomics, and network pharmacology.
Wang Z, Zhang S, Li S, Zhao G, Zhang Y, Zhang X, Sun M, Lu Y, Song E, Quan C, Lv C, Wang Y
Journal of translational medicine 2025 Oct 27;23(1):1177
Journal of translational medicine 2025 Oct 27;23(1):1177
Gut symbiont-derived ursodeoxycholic acid promotes fatty acid oxidation to protect against renal ischemia-reperfusion injury.
Xie M, Zheng J, Yu Y, Yang Q, Zhou Z, Xue J, Wang B, Qiu Y, Zhu Z, Sun Q, Shi X, Shangguan W, Li L, Zou Z, Zhao J, Wu P
Cell reports. Medicine 2025 Oct 21;6(10):102373
Cell reports. Medicine 2025 Oct 21;6(10):102373
Co-administration of berberine and evodiamine: Mitigating evodiamine-induced hepatotoxicity and potentiating colitis treatment.
Tao X, Gao Y, Jin Z, Lu S, Li Z, Guo S, Fan Q, Li J, Qiao C, Lei H, Zhang Z, Zhao C, Wu J
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov;147:157185
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov;147:157185
Inhalation of Ultrafine Carbon Black-Induced Mitochondrial Dysfunction in Mouse Heart Through Changes in Acetylation.
Islam R, Stewart JE, Mullen WE, Lin D, Hussain S, Thapa D
Cells 2025 Nov 4;14(21)
Cells 2025 Nov 4;14(21)
Dietary combination of sucrose and linoleic acid increases intramyocellular lipid and impairs muscle strength in female Zucker diabetic fatty rats.
Takikawa M, Ohminami H, Uchida T, Kitamura A, Adachi Y, Mori Y, Ohnishi K, Masuda M, Yamanaka-Okumura H, Taketani Y
Journal of clinical biochemistry and nutrition 2025 May;76(3):271-279
Journal of clinical biochemistry and nutrition 2025 May;76(3):271-279
The inhibition of PPARα protein degradation alleviates the cardiotoxicity of Tiebangchui by regulating fatty acid metabolism.
Liu X, Yang L, Zhou R, Zhang T, Xu L, Liu Y, Zhang Y, Meng X
Journal of ethnopharmacology 2025 May 28;348:119838
Journal of ethnopharmacology 2025 May 28;348:119838
A cold-inducible phospholipid-protein interaction in brown fat mitochondria optimizes thermogenic capacity.
Shimanaka Y, Tol MJ, Rocha-Roa C, Jellinek MJ, Cui L, Bender A, Bedard AH, Milner MG, Melillo B, Shoucri BM, Wong A, Williams KJ, Stiles L, Shum M, Weston TA, Cohn W, Whitelegge JP, Budin I, Bertholet AM, Cravatt BF, Young SG, Houten SM, Argmann C, Ford DA, Liesa M, Shirihai OS, Vanni S, Tontonoz P
bioRxiv : the preprint server for biology 2025 May 18;
bioRxiv : the preprint server for biology 2025 May 18;
Integrative analysis of genes provides insights into the molecular and immune characteristics of mitochondria-related genes in atherosclerosis.
Zheng Z, Lu H, Wang X, Yang Z, Zhang Y, Li K, Shen C, Yin Z, Sha M, Ye J, Zhu L
Genomics 2025 Mar;117(2):111013
Genomics 2025 Mar;117(2):111013
Etomoxir suppresses the expression of PPARγ2 and inhibits the thermogenic gene induction of brown adipocytes through pathways other than β-oxidation inhibition.
Shimura H, Yamamoto S, Shiiba I, Oikawa M, Uchinomiya S, Ojida A, Yanagi S, Kadowaki H, Nishitoh H, Fukuda T, Nagashima S, Yamaguchi T
Journal of biochemistry 2025 Mar 4;177(3):203-212
Journal of biochemistry 2025 Mar 4;177(3):203-212
Inhibition of serotonin-Htr2b signaling in skeletal muscle mitigates obesity-induced insulin resistance.
Park S, Kim H, Shin S, Kim Y, Kang Y, Cha HN, Park SY, Park S, Oh CM
Experimental & molecular medicine 2025 Jun;57(6):1177-1188
Experimental & molecular medicine 2025 Jun;57(6):1177-1188
Early-life exercise extends healthspan but not lifespan in mice.
Feng M, Li M, Lou J, Wu G, Gao T, Wu F, Tan Y, Zhang N, Zhao Y, Zhao L, Li J, Shi C, Zhang X, Liu J, Gao F
Nature communications 2025 Jul 9;16(1):6328
Nature communications 2025 Jul 9;16(1):6328
The role of quercetin in modulating lipid metabolism and enhancing chemotherapy via the STAT3-CPT1B pathway in pancreatic cancer.
Huang X, Wen Z, Cai H, Yu D
Biochemical and biophysical research communications 2025 Jul 30;772:152033
Biochemical and biophysical research communications 2025 Jul 30;772:152033
Qifu Decoction Alleviates Lipopolysaccharide-Induced Myocardial Dysfunction by Inhibiting TLR4/NF-κB/NLRP3 Inflammatory Pathway and Activating PPARα/CPT Pathway.
Zhuo L, Ma M, Zhang J, Zhou J, Zheng Y, Liang A, Sun Q, Liu J, Liao W
Pharmaceuticals (Basel, Switzerland) 2025 Jul 25;18(8)
Pharmaceuticals (Basel, Switzerland) 2025 Jul 25;18(8)
Reversing metabolic reprogramming by CPT1 inhibition with etomoxir promotes cardiomyocyte proliferation and heart regeneration via DUSP1 ADP-ribosylation-mediated p38 MAPK phosphorylation.
Tang L, Shi Y, Liao Q, Wang F, Wu H, Ren H, Wang X, Fu W, Shou J, Wang WE, Jose PA, Yang Y, Zeng C
Acta pharmaceutica Sinica. B 2025 Jan;15(1):256-277
Acta pharmaceutica Sinica. B 2025 Jan;15(1):256-277
Sex Differences in Response to Diet Enriched With Glutathione Precursors in the Aging Heart.
Angelini A, Garcia Marquez G, Malovannaya A, Fiorotto ML, Saltzman A, Jain A, Trial J, Taffet GE, Cieslik KA
The journals of gerontology. Series A, Biological sciences and medical sciences 2025 Jan 16;80(2)
The journals of gerontology. Series A, Biological sciences and medical sciences 2025 Jan 16;80(2)
Moderate-intensity interval exercise exacerbates cardiac lipotoxicity in high-fat, high-calories diet-fed mice.
Geng J, Zhang X, Guo Y, Wen H, Guo D, Liang Q, Pu S, Wang Y, Liu M, Li Z, Hu W, Yang X, Chang P, Hu L, Li Y
Nature communications 2025 Jan 12;16(1):613
Nature communications 2025 Jan 12;16(1):613
Trans 10, cis 12-conjugated linoleic acid in low concentration reduces while in high concentration enhances adipocyte metabolism but effectively improves hepatic steatosis of obese mice.
Rao Y, Yu S, Liang L, Wang Q, Lu J, Wang B, Gou K
The Journal of nutritional biochemistry 2025 Feb;136:109801
The Journal of nutritional biochemistry 2025 Feb;136:109801
FGF21 protects against HFpEF by improving cardiac mitochondrial bioenergetics in mice.
Zhang K, Gan J, Wang B, Lei W, Zhen D, Yang J, Wang N, Wen C, Gao X, Li X, Xu A, Liu X, Li Y, Wu F, Lin Z
Nature communications 2025 Feb 15;16(1):1661
Nature communications 2025 Feb 15;16(1):1661
BMP10 attenuates age-related atrial fibrillation susceptibility through improving mitochondrial function in atrial cardiomyocytes.
Gao Q, Cao Y, Zhao X, Mu H, Li Y, Yuan Y
Archives of gerontology and geriatrics 2025 Dec;139:105997
Archives of gerontology and geriatrics 2025 Dec;139:105997
(-)-Guaiol Downregulates M2 Tumor-Associated Macrophage Polarization Through PPAR-γ Signaling to Suppress Lung Cancer.
Zhao ZY, Wu JC, Luo YB, Wang YL, Wang X, Tian JH, Zhang B, Li Y
Biological procedures online 2025 Dec 5;28(1):1
Biological procedures online 2025 Dec 5;28(1):1
Gallic Acid Ameliorates Skeletal Muscle Metabolic Inflexibility by Regulating Lactate Metabolism and Promoting Mitochondrial Function.
Wang Y, Wang F, Sun J, Xue L, Sun Y, Zhang K, Fan M, Qian H, Yang B, Du J, Li Y, Wang L
Molecular nutrition & food research 2025 Aug;69(16):e70106
Molecular nutrition & food research 2025 Aug;69(16):e70106
Ankyrin-B modulates mitochondrial fission in skeletal muscle and is required for optimal endurance exercise capacity.
Voos KM, Tzeng J, Patel P, Rubinsky S, Choi HE, Pharr T, Sookram S, Baur JA, Soderblom EJ, Lorenzo DN
Nature communications 2025 Aug 25;16(1):7671
Nature communications 2025 Aug 25;16(1):7671
The TEX44-CPT1B axis regulates mitochondrial sheath assembly and fatty acid oxidation in sperm.
Zhi E, Bai H, Ren C, Dong Y, Zhang J, Xu Y, Tan C, Pan Y, Zhou L, Li P, Tan Y, Zhou Y, Meng L, Xu J, Zhang Y, Xu S, Ji Z, Zhao L, Jiang M, Li Z, Yao C, Zhou Y, Wu J, Yang X, Liu S, Liu M
Nature communications 2025 Aug 23;16(1):7864
Nature communications 2025 Aug 23;16(1):7864
2-Methoxyestradiol ameliorates doxorubicin-induced cardiotoxicity by regulating the expression of GLUT4 and CPT-1B in female rats.
Sobhy MH, Ismail A, Abdel-Hamid MS, Wagih M, Kamel M
Naunyn-Schmiedeberg's archives of pharmacology 2024 Sep;397(9):7129-7139
Naunyn-Schmiedeberg's archives of pharmacology 2024 Sep;397(9):7129-7139
S-1-Propenylcysteine Enhances Endurance Capacity of Mice by Stimulating Fatty Acid Metabolism via Muscle Isoform of Carnitine Acyltransferase-1.
Kunimura K, Nakamoto M, Ushijima M
The Journal of nutrition 2024 Sep;154(9):2707-2716
The Journal of nutrition 2024 Sep;154(9):2707-2716
Etomoxir repurposed as a promiscuous fatty acid mimetic chemoproteomic probe.
Choi J, Smith DM, Lee YJ, Cai D, Hossain MJ, O'Connor TJ, Deme P, Haughey NJ, Scafidi S, Riddle RC, Wolfgang MJ
iScience 2024 Sep 20;27(9):110642
iScience 2024 Sep 20;27(9):110642
Epicatechin and β-glucan from whole highland barley grain ameliorates hyperlipidemia associated with attenuating intestinal barrier dysfunction and modulating gut microbiota in high-fat-diet-fed mice.
Liu Z, Tang R, Liu J, Zhang Z, Li Y, Zhao R
International journal of biological macromolecules 2024 Oct;278(Pt 3):134917
International journal of biological macromolecules 2024 Oct;278(Pt 3):134917
Systemic inhibition of mitochondrial fatty acid β-oxidation impedes zebrafish ventricle regeneration.
Zhao Y, Lv H, Yu C, Liang J, Yu H, Du Z, Zhang R
Biochimica et biophysica acta. Molecular basis of disease 2024 Oct;1870(7):167442
Biochimica et biophysica acta. Molecular basis of disease 2024 Oct;1870(7):167442
Involvement of mitochondrial fatty acid β-oxidation in the antiviral innate immune response in head kidney macrophages of large yellow croaker (Larimichthys crocea).
Liu Q, Chen Z, Zhang J, Pan S, Zhou Y, Tang Y, Wu C, Wang H, Zhao Z, Li Y, Mai K, Ai Q
Fish & shellfish immunology 2024 Oct;153:109829
Fish & shellfish immunology 2024 Oct;153:109829
The ZNF263/CPT1B axis regulates fatty acid β-oxidation to affect cisplatin resistance in lung adenocarcinoma.
Yan R, Zheng C, Qian S, Li K, Kong X, Liao S
The pharmacogenomics journal 2024 Nov 5;24(6):33
The pharmacogenomics journal 2024 Nov 5;24(6):33
Transgenic female mice producing trans 10, cis 12-conjugated linoleic acid present excessive prostaglandin E2, adrenaline, corticosterone, glucagon, and FGF21.
Rao Y, Liang LW, Li MJ, Wang YY, Wang BZ, Gou KM
Scientific reports 2024 May 30;14(1):12430
Scientific reports 2024 May 30;14(1):12430
APC/C-regulated CPT1C promotes tumor progression by upregulating the energy supply and accelerating the G1/S transition.
Zhao H, Cheng X, Yan L, Mi F, Wang W, Hu Y, Liu X, Fan Y, Min Q, Wang Y, Zhang W, Wu Q, Zhan Q
Cell communication and signaling : CCS 2024 May 23;22(1):283
Cell communication and signaling : CCS 2024 May 23;22(1):283
Low phosphorus increases hepatic lipid deposition, oxidative stress and inflammatory response via Acetyl-CoA carboxylase-dependent manner in zebrafish liver cells.
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Chinese medicine 2024 Jun 11;19(1):82
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The Journal of biological chemistry 2024 Jul;300(7):107426
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The Journal of cell biology 2024 Dec 2;223(12)
The Journal of cell biology 2024 Dec 2;223(12)
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Life science alliance 2024 Aug;7(8)
Life science alliance 2024 Aug;7(8)
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PloS one 2023;18(11):e0289086
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The Journal of nutritional biochemistry 2023 Oct;120:109419
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Nutrients 2023 Oct 29;15(21)
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International journal of molecular sciences 2023 Oct 24;24(21)
International journal of molecular sciences 2023 Oct 24;24(21)
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European journal of pharmacology 2023 May 15;947:175676
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Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Dec;10(34):e2304895
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Dec;10(34):e2304895
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American journal of physiology. Regulatory, integrative and comparative physiology 2023 Dec 1;325(6):R809-R819
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Journal of molecular and cellular cardiology 2023 Aug;181:33-45
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Frontiers in nutrition 2022;9:849684
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Frontiers in cardiovascular medicine 2022;9:727474
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International journal of biological sciences 2022;18(7):3082-3101
International journal of biological sciences 2022;18(7):3082-3101
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The Journal of physiology 2022 Feb;600(3):655-670
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Frontiers in cell and developmental biology 2021;9:627135
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Frontiers in cardiovascular medicine 2021;8:722908
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American journal of physiology. Heart and circulatory physiology 2016 Jul 1;311(1):H64-75
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The CPT1B-specific antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human CPT1B-specific. This antibody recognizes human, mouse antigen. The CPT1B-specific antibody has been validated for the following applications: ELISA, WB analysis.
