Antibody data
- Antibody Data
- Antigen structure
- References [21]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- 22170-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#22170-1-AP, RRID:AB_2713959
- Product name
- CPT1B-specific antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated CPT1B-specific antibody (Cat. #22170-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references The Protective Effect of 1,25(OH)2D3 on Myocardial Function is Mediated via Sirtuin 3-Regulated Fatty Acid Metabolism.
FABP3 Deficiency Exacerbates Metabolic Derangement in Cardiac Hypertrophy and Heart Failure via PPARα Pathway.
Bawei Chenxiang Wan Ameliorates Cardiac Hypertrophy by Activating AMPK/PPAR-α Signaling Pathway Improving Energy Metabolism.
PHDs/CPT1B/VDAC1 axis regulates long-chain fatty acid oxidation in cardiomyocytes.
Exercise promotes angiogenesis by enhancing endothelial cell fatty acid utilization via liver-derived extracellular vesicle miR-122-5p.
Exercise improves lipid metabolism disorders induced by high-fat diet in a SESN2/JNK-independent manner.
LEFTY-PITX2 signaling pathway is critical for generation of mature and ventricular cardiac organoids in human pluripotent stem cell-derived cardiac mesoderm cells.
Intrauterine growth restriction elevates circulating acylcarnitines and suppresses fatty acid metabolism genes in the fetal sheep heart.
Short-term but not long-term high fat diet feeding protects against pressure overload-induced heart failure through activation of mitophagy.
Combined effects of a ketogenic diet and exercise training alter mitochondrial and peroxisomal substrate oxidative capacity in skeletal muscle.
Nanoparticle-Mediated Lipid Metabolic Reprogramming of T Cells in Tumor Microenvironments for Immunometabolic Therapy.
Aging Influences the Metabolic and Inflammatory Phenotype in an Experimental Mouse Model of Acute Lung Injury.
Targeting CPT1B as a potential therapeutic strategy in castration-resistant and enzalutamide-resistant prostate cancer.
Peroxisomal proliferator-activated receptor α-b deficiency induces the reprogramming of nutrient metabolism in zebrafish.
LncRNAH19 improves insulin resistance in skeletal muscle by regulating heterogeneous nuclear ribonucleoprotein A1.
Modulation of Fatty Acid-Related Genes in the Response of H9c2 Cardiac Cells to Palmitate and n-3 Polyunsaturated Fatty Acids.
Cardiac-specific LRP6 knockout induces lipid accumulation through Drp1/CPT1b pathway in adult mice.
Novel metabolic disorders in skeletal muscle of Lipodystrophic Bscl2/Seipin deficient mice.
PGC-1α Participates in the Protective Effect of Chronic Intermittent Hypobaric Hypoxia on Cardiomyocytes.
Global Analysis of Plasma Lipids Identifies Liver-Derived Acylcarnitines as a Fuel Source for Brown Fat Thermogenesis.
TXNIP regulates myocardial fatty acid oxidation via miR-33a signaling.
Yang J, Zhang Y, Pan Y, Sun C, Liu Z, Liu N, Fu Y, Li X, Li Y, Kong J
Frontiers in cell and developmental biology 2021;9:627135
Frontiers in cell and developmental biology 2021;9:627135
FABP3 Deficiency Exacerbates Metabolic Derangement in Cardiac Hypertrophy and Heart Failure via PPARα Pathway.
Zhuang L, Mao Y, Liu Z, Li C, Jin Q, Lu L, Tao R, Yan X, Chen K
Frontiers in cardiovascular medicine 2021;8:722908
Frontiers in cardiovascular medicine 2021;8:722908
Bawei Chenxiang Wan Ameliorates Cardiac Hypertrophy by Activating AMPK/PPAR-α Signaling Pathway Improving Energy Metabolism.
Zhang X, Zhang Z, Wang P, Han Y, Liu L, Li J, Chen Y, Liu D, Wang J, Tian X, Zhao Q, Yan F
Frontiers in pharmacology 2021;12:653901
Frontiers in pharmacology 2021;12:653901
PHDs/CPT1B/VDAC1 axis regulates long-chain fatty acid oxidation in cardiomyocytes.
Angelini A, Saha PK, Jain A, Jung SY, Mynatt RL, Pi X, Xie L
Cell reports 2021 Oct 5;37(1):109767
Cell reports 2021 Oct 5;37(1):109767
Exercise promotes angiogenesis by enhancing endothelial cell fatty acid utilization via liver-derived extracellular vesicle miR-122-5p.
Lou J, Wu J, Feng M, Dang X, Wu G, Yang H, Wang Y, Li J, Zhao Y, Shi C, Liu J, Zhao L, Zhang X, Gao F
Journal of sport and health science 2021 Oct 1;
Journal of sport and health science 2021 Oct 1;
Exercise improves lipid metabolism disorders induced by high-fat diet in a SESN2/JNK-independent manner.
Wang T, Hu W, Niu Y, Liu S, Fu L
Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme 2021 Nov;46(11):1322-1330
Applied physiology, nutrition, and metabolism = Physiologie appliquee, nutrition et metabolisme 2021 Nov;46(11):1322-1330
LEFTY-PITX2 signaling pathway is critical for generation of mature and ventricular cardiac organoids in human pluripotent stem cell-derived cardiac mesoderm cells.
Song MH, Choi SC, Noh JM, Joo HJ, Park CY, Cha JJ, Ahn TH, Ko TH, Choi JI, Na JE, Rhyu IJ, Jang Y, Park Y, Gim JA, Kim JH, Lim DS
Biomaterials 2021 Nov;278:121133
Biomaterials 2021 Nov;278:121133
Intrauterine growth restriction elevates circulating acylcarnitines and suppresses fatty acid metabolism genes in the fetal sheep heart.
Drake RR, Louey S, Thornburg KL
The Journal of physiology 2021 Nov 21;
The Journal of physiology 2021 Nov 21;
Short-term but not long-term high fat diet feeding protects against pressure overload-induced heart failure through activation of mitophagy.
Tan Y, Li M, Wu G, Lou J, Feng M, Xu J, Zhou J, Zhang P, Yang H, Dong L, Li J, Zhang X, Gao F
Life sciences 2021 May 1;272:119242
Life sciences 2021 May 1;272:119242
Combined effects of a ketogenic diet and exercise training alter mitochondrial and peroxisomal substrate oxidative capacity in skeletal muscle.
Huang TY, Linden MA, Fuller SE, Goldsmith FR, Simon J, Batdorf HM, Scott MC, Essajee NM, Brown JM, Noland RC
American journal of physiology. Endocrinology and metabolism 2021 Jun 1;320(6):E1053-E1067
American journal of physiology. Endocrinology and metabolism 2021 Jun 1;320(6):E1053-E1067
Nanoparticle-Mediated Lipid Metabolic Reprogramming of T Cells in Tumor Microenvironments for Immunometabolic Therapy.
Kim D, Wu Y, Li Q, Oh YK
Nano-micro letters 2021 Jan 4;13(1):31
Nano-micro letters 2021 Jan 4;13(1):31
Aging Influences the Metabolic and Inflammatory Phenotype in an Experimental Mouse Model of Acute Lung Injury.
Gibbs KW, Chuang Key CC, Belfield L, Krall J, Purcell L, Liu C, Files DC
The journals of gerontology. Series A, Biological sciences and medical sciences 2021 Apr 30;76(5):770-777
The journals of gerontology. Series A, Biological sciences and medical sciences 2021 Apr 30;76(5):770-777
Targeting CPT1B as a potential therapeutic strategy in castration-resistant and enzalutamide-resistant prostate cancer.
Abudurexiti M, Zhu W, Wang Y, Wang J, Xu W, Huang Y, Zhu Y, Shi G, Zhang H, Zhu Y, Shen Y, Dai B, Wan F, Lin G, Ye D
The Prostate 2020 Sep;80(12):950-961
The Prostate 2020 Sep;80(12):950-961
Peroxisomal proliferator-activated receptor α-b deficiency induces the reprogramming of nutrient metabolism in zebrafish.
Li LY, Lv HB, Jiang ZY, Qiao F, Chen LQ, Zhang ML, Du ZY
The Journal of physiology 2020 Oct;598(20):4537-4553
The Journal of physiology 2020 Oct;598(20):4537-4553
LncRNAH19 improves insulin resistance in skeletal muscle by regulating heterogeneous nuclear ribonucleoprotein A1.
Gui W, Zhu WF, Zhu Y, Tang S, Zheng F, Yin X, Lin X, Li H
Cell communication and signaling : CCS 2020 Oct 28;18(1):173
Cell communication and signaling : CCS 2020 Oct 28;18(1):173
Modulation of Fatty Acid-Related Genes in the Response of H9c2 Cardiac Cells to Palmitate and n-3 Polyunsaturated Fatty Acids.
Cetrullo S, D'Adamo S, Panichi V, Borzì RM, Pignatti C, Flamigni F
Cells 2020 Feb 26;9(3)
Cells 2020 Feb 26;9(3)
Cardiac-specific LRP6 knockout induces lipid accumulation through Drp1/CPT1b pathway in adult mice.
Wang Y, Yin C, Chen Z, Li Y, Zou Y, Wang X, An Y, Wu F, Zhang G, Yang C, Tang H, Zou Y, Gong H
Cell and tissue research 2020 Apr;380(1):143-153
Cell and tissue research 2020 Apr;380(1):143-153
Novel metabolic disorders in skeletal muscle of Lipodystrophic Bscl2/Seipin deficient mice.
Xu W, Zhou H, Xuan H, Saha P, Wang G, Chen W
Molecular and cellular endocrinology 2019 Feb 15;482:1-10
Molecular and cellular endocrinology 2019 Feb 15;482:1-10
PGC-1α Participates in the Protective Effect of Chronic Intermittent Hypobaric Hypoxia on Cardiomyocytes.
Gu S, Hua H, Guo X, Jia Z, Zhang Y, Maslov LN, Zhang X, Ma H
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;50(5):1891-1902
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2018;50(5):1891-1902
Global Analysis of Plasma Lipids Identifies Liver-Derived Acylcarnitines as a Fuel Source for Brown Fat Thermogenesis.
Simcox J, Geoghegan G, Maschek JA, Bensard CL, Pasquali M, Miao R, Lee S, Jiang L, Huck I, Kershaw EE, Donato AJ, Apte U, Longo N, Rutter J, Schreiber R, Zechner R, Cox J, Villanueva CJ
Cell metabolism 2017 Sep 5;26(3):509-522.e6
Cell metabolism 2017 Sep 5;26(3):509-522.e6
TXNIP regulates myocardial fatty acid oxidation via miR-33a signaling.
Chen J, Young ME, Chatham JC, Crossman DK, Dell'Italia LJ, Shalev A
American journal of physiology. Heart and circulatory physiology 2016 Jul 1;311(1):H64-75
American journal of physiology. Heart and circulatory physiology 2016 Jul 1;311(1):H64-75
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Supportive validation
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- Proteintech Group (provider)
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- Experimental details
- The CPT1B-specific antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human CPT1B-specific. This antibody recognizes human, mouse antigen. The CPT1B-specific antibody has been validated for the following applications: ELISA, WB analysis.