Tissue expression
Cell line expression
Protein structure

DOCK2

Dedicator of cytokinesis 2
KIAA0209 
The protein encoded by this gene belongs to the CDM protein family. It is specifically expressed in hematopoietic cells and is predominantly expressed in peripheral blood leukocytes. The protein is involved in remodeling of the actin cytoskeleton required for lymphocyte migration in response to chemokine signaling. It activates members of the Rho family of GTPases, for example RAC1 and RAC2, by acting as a guanine nucleotide exchange factor (GEF) to exchange bound GDP for free GTP. Mutations in this gene result in immunodeficiency 40 (IMD40), a combined form of immunodeficiency that affects T cell number and function, also with variable defects in B cell and NK cell function. [provided by RefSeq, May 2018]
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308 antibodies from 32 providers.

Antibody properties

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AntibodyRefsTypeWBELICCIPIHCFC
St John's Laboratory
2 antibodies
Proteintech Group
3 antibodies
Invitrogen Antibodies
25 antibodies
Biorbyt
61 antibodies
OriGene
19 antibodies
Atlas Antibodies
1 antibody
antibodies-online
56 antibodies
Affinity Biosciences
1 antibody
Novus Biologicals
27 antibodies
GeneTex
2 antibodies
Cusabio Biotech Co., Ltd
2 antibodies
Boster Biological Technology
3 antibodies
Bethyl Laboratories
2 antibodies
NovoPro Bioscience Inc.
2 antibodies
Cell Signaling Technology, Inc
1 antibody
Abnova Corporation
3 antibodies
MyBioSource
4 antibodies
RabMAbs
2 antibodies
Arigo
1 antibody
Aviva Systems Biology
1 antibody
R&D Systems
1 antibody
Abiocode, Inc.
1 antibody
Creative Biolabs
5 antibodies
Creative Diagnostics
2 antibodies
Abbexa
4 antibodies
Abbkine Scientific Co.Ltd.
1 antibody
United States Biological
13 antibodies
Leading Biology
2 antibodies
MilliporeSigma / Merck KGaA
3 antibodies
EMD Millipore
1 antibody