17077-1-AP

antibody from Proteintech Group

Targeting: PIP4K2C FLJ22055, PIP5K2C

Western blot (Data presented on provider website)

ELISA (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

17077-1-AP

Provider

Proteintech Group

Proper citation

Proteintech Cat#17077-1-AP, RRID:AB_2715526

Product name

PIP4K2C antibody

Antibody type

Polyclonal

Description

KD/KO validated PIP4K2C antibody (Cat. #17077-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, WB,ELISA.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

20ul, 150ul

References

Submitted references

A proximity-labeling map of PI5P4K phosphoinositide kinases interaction networks.

Llorente A, Arora GK, Loughran RM, Murad R, Maurya S, Crabtree S, Portillo B, Chapagain P, Huluka H, Eron S, Goodman K, Ye G, Blind RD, Emerling BM
The Journal of biological chemistry 2026 Apr 24;:113071

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Orthosteric-allosteric dual inhibitors of PI5P4Kγ with potent antitumor activity in non-small cell lung cancer.

Xiong L, Tang 唐磊 L, Zhao W, Wang R, Cheng C, Wang D, Xu Y, Tang 汤磊 L, Fan Y
Journal of advanced research 2025 Sep 22;

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Traditional wisdom meets modern science: The protective role of sanhuang shu'ai decoction in ulcerative colitis models.

Zhang N, Liu A, Cao M, Han Z, Guo D, Zhang S, Zhang J
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Nov;147:157163

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Downregulation of PIP4K2C inhibits the breast cancer cell proliferation, migration and invasion.

Jin Y, Xue J, Li X, Zhong X
Translational oncology 2025 Jul;57:102420

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Upregulation of the ESCRT pathway and multivesicular bodies accelerates degradation of proteins associated with neurodegeneration.

Benyair R, Giridharan SSP, Rivero-Ríos P, Hasegawa J, Bristow E, Eskelinen EL, Shmueli MD, Fishbain-Yoskovitz V, Merbl Y, Sharkey LM, Paulson HL, Hanson PI, Patnaik S, Al-Ramahi I, Botas J, Marugan J, Weisman LS
Autophagy reports 2023;2(1)

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PIP4Ks Suppress Insulin Signaling through a Catalytic-Independent Mechanism.

Wang DG, Paddock MN, Lundquist MR, Sun JY, Mashadova O, Amadiume S, Bumpus TW, Hodakoski C, Hopkins BD, Fine M, Hill A, Yang TJ, Baskin JM, Dow LE, Cantley LC
Cell reports 2019 May 14;27(7):1991-2001.e5

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Inhibition of PIP4Kγ ameliorates the pathological effects of mutant huntingtin protein.

Al-Ramahi I, Giridharan SSP, Chen YC, Patnaik S, Safren N, Hasegawa J, de Haro M, Wagner Gee AK, Titus SA, Jeong H, Clarke J, Krainc D, Zheng W, Irvine RF, Barmada S, Ferrer M, Southall N, Weisman LS, Botas J, Marugan JJ
eLife 2017 Dec 26;6