66514-1-Ig

antibody from Proteintech Group

Targeting: USP7 HAUSP

Western blot (Data presented on provider website)

ELISA (Data presented on provider website)

Immunocytochemistry (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

66514-1-Ig

Provider

Proteintech Group

Product name

USP7 antibody

Antibody type

Monoclonal

Description

USP7 antibody (Cat. #66514-1-Ig) is a mouse monoclonal antibody that shows reactivity with Human, rat, mouse and has been validated for the following applications: IF, IHC, WB,ELISA.

Reactivity

Human, Mouse, Rat

Host

Mouse

Conjugate

Unconjugated

Isotype

IgG

Antibody clone number

3D7D11

Vial size

20ul, 150ul

References

Submitted references

TMEM43 promotes the development of hepatocellular carcinoma by activating VDAC1 through USP7 deubiquitination.

Zhang N, Wang F, Yang X, Wang Q, Chang R, Zhu L, Feitelson MA, Chen Z
Translational gastroenterology and hepatology 2024;9:9

---

The Long Non-Coding RNA NR3C2-8:1 Promotes p53-Mediated Apoptosis through the miR-129-5p/USP10 Axis in Amyotrophic Lateral Sclerosis.

Pang D, Yu Y, Zhao B, Huang J, Cui Y, Li T, Li C, Shang H
Molecular neurobiology 2024 Oct;61(10):7466-7480

---

Guanosine diphosphate-mannose suppresses homologous recombination repair and potentiates antitumor immunity in triple-negative breast cancer.

Ding JH, Xiao Y, Yang F, Song XQ, Xu Y, Ding XH, Ding R, Shao ZM, Di GH, Jiang YZ
Science translational medicine 2024 Jan 3;16(728):eadg7740

---

Stabilization of KPNB1 by deubiquitinase USP7 promotes glioblastoma progression through the YBX1-NLGN3 axis.

Li J, Zhang B, Feng Z, An D, Zhou Z, Wan C, Hu Y, Sun Y, Wang Y, Liu X, Wei W, Yang X, Meng J, Che M, Sheng Y, Wu B, Wen L, Huang F, Li Y, Yang K
Journal of experimental & clinical cancer research : CR 2024 Jan 23;43(1):28

---

CRIP1 involves the pathogenesis of multiple myeloma via dual-regulation of proteasome and autophagy.

Tang P, Yu Z, Sun H, Liu L, Gong L, Fang T, Sun X, Xie S, An G, Xu Z, Qiu L, Hao M
EBioMedicine 2024 Feb;100:104961

---

A TOPBP1 allele causing male infertility uncouples XY silencing dynamics from sex body formation.

Ascenção C, Sims JR, Dziubek A, Comstock W, Fogarty EA, Badar J, Freire R, Grimson A, Weiss RS, Cohen PE, Smolka MB
eLife 2024 Feb 23;12

---

The CTLH Ubiquitin Ligase Substrates ZMYND19 and MKLN1 Negatively Regulate mTORC1 at the Lysosomal Membrane.

Wang Y, Guo R, Piedras BI, Tang HY, Asara JM, Tempera I, Lieberman PM, Gewurz BE
Research square 2024 Apr 24;

---

USP7 reduction leads to developmental failure of mouse early embryos.

Zhang X, Xie XF, Li A, Song W, Li C, Li F, Li XZ, Fan XY, Zhou CY, Wang G, Sun QY, Ou XH
Experimental cell research 2023 Jun 15;427(2):113605

---

Metabolite asymmetric dimethylarginine (ADMA) functions as a destabilization enhancer of SOX9 mediated by DDAH1 in osteoarthritis.

Wu Y, Shen S, Chen J, Ni W, Wang Q, Zhou H, Chen J, Zhang H, Mei Z, Sun X, Shen P, Jie Z, Xu W, Hong Z, Ma Y, Wang K, Wan S, Wu H, Xie Z, Qin A, Fan S
Science advances 2023 Feb 10;9(6):eade5584

---

Increased degradation of FMRP contributes to neuronal hyperexcitability in tuberous sclerosis complex.

Winden KD, Pham TT, Teaney NA, Ruiz J, Chen R, Chen C, Sahin M
Cell reports 2023 Aug 29;42(8):112838

---

The deubiquitinase USP7 regulates oxidative stress through stabilization of HO-1.

Gao M, Qi Z, Deng M, Huang H, Xu Z, Guo G, Jing J, Huang X, Xu M, Kloeber JA, Liu S, Huang J, Lou Z, Han J
Oncogene 2022 Aug;41(33):4018-4027

---

Indirubin-3'-monoxime acts as proteasome inhibitor: Therapeutic application in multiple myeloma.

Yu Z, Wei X, Liu L, Sun H, Fang T, Wang L, Li Y, Sui W, Wang K, He Y, Zhao Y, Huang W, An G, Meng F, Huang C, Yu T, Anderson KC, Cheng T, Qiu L, Hao M
EBioMedicine 2022 Apr;78:103950

---

Deubiquitination of FBP1 by USP7 blocks FBP1-DNMT1 interaction and decreases the sensitivity of pancreatic cancer cells to PARP inhibitors.

Cheng X, Zhang B, Guo F, Wu H, Jin X
Molecular oncology 2022 Apr;16(7):1591-1607

---

The role of USP7 in the Shoc2-ERK1/2 signaling axis and Noonan-like syndrome with loose anagen hair.

Wilson P, Abdelmoti L, Norcross R, Jang ER, Palayam M, Galperin E
Journal of cell science 2021 Nov 1;134(21)

---

BK Channel Deficiency in Osteoblasts Reduces Bone Formation via the Wnt/β-Catenin Pathway.

Jiang L, Yang Q, Gao J, Yang J, He J, Xin H, Zhang X
Molecules and cells 2021 Aug 31;44(8):557-568

---

TRIM21-SERPINB5 aids GMPS repression to protect nasopharyngeal carcinoma cells from radiation-induced apoptosis.

Zhang P, Li X, He Q, Zhang L, Song K, Yang X, He Q, Wang Y, Hong X, Ma J, Liu N
Journal of biomedical science 2020 Jan 31;27(1):30