Ab122822

antibody from Aladdin Scientific
Targeting: PPP1CB MP, PP-1B, PP1B, PP1beta, PP1c, PPP1beta
Provider product page for Ab122822

Antibody data

Product number
Ab122822 - Provider product page
Provider
Aladdin Scientific
Product name
Recombinant PPP1CB Antibody
Antibody type
Recombinant
Description
Rabbit anti Human PPP1CB Antibody, Recombinant, could be used for WB, IHC, ICC/IF and so on.Application:WB: 1/500-1/1000IHC: 1/50-1/100ICC/IF: 1/50-1/200Protein FunctionProtein phosphatase that associates with over 200 regulatory proteins to form highly specific holoenzymes which dephosphorylate hundreds of biological targets. Protein phosphatase (PP1) is essential for cell division, it participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. Involved in regulation of ionic conductances and long-term synaptic plasticity. Component of the PTW/PP1 phosphatase complex, which plays a role in the control of chromatin structure and cell cycle progression during the transition from mitosis into interphase. In balance with CSNK1D and CSNK1E, determines the circadian period length, through the regulation of the speed and rhythmicity of PER1 and PER2 phosphorylation. May dephosphorylate CSNK1D and CSNK1E. Dephosphorylates the 'Ser-418' residue of FOXP3 in regulatory T-cells (Treg) from patients with rheumatoid arthritis, thereby inactivating FOXP3 and rendering Treg cells functionally defective (PubMed:23396208).
Reactivity
Human, Mouse, Rat
Host
Rabbit
Conjugate
Unconjugated
Antigen sequence
AA 314-327
Vial size
100_l,10_l,1ml,50_l
Concentration
0,4 mg/ml
Storage
Store at 4¡C short term (1-2 weeks). Store at -20¡C long term (24 months). Upon delivery aliquot. Avoid freeze/thaw cycle.
PPP1CB protein structure - Ab122822 shown in red.