BS8142

antibody from Bioworld Technology, Inc
Targeting: CIAPIN1 Anamorsin, CIAE2
Provider product page for BS8142
Western blot
Immunohistochemistry

Antibody data

Product number
BS8142 - Provider product page
Provider
Bioworld Technology, Inc
Product name
CIAPIN1 polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human CIAPIN1.
Description
The name of the protein Anamorsin, also designated cytokine-induced apoptosis inhibitor 1 (CIAPIN1), comes from the Latin term ¡ùana-mors-in¡ì, meaning ¡ùanti-death molecule¡ì. During hematopoiesis, Anamorsin is crucial for mediating the anti-apoptotic effects of various cytokines. It is a ubiquitously expressed protein, and when it is overexpressed, it confers apoptotic resistance. Anamorsin is primarily expressed in the cytoplasm of liver, pancreas and heart tissue cells and does not show any homology to known apoptosis regulatory molecules of the Bcl-2 or CASP families, or to signal transduction molecules. Anamorsin expression in mouse cells confers resistance to apoptosis caused by IL-3 (interleukin-3) deprivation. Studies demonstrate that the addition of growth factors, such as EPO (erythropoietin), SCF (stem cell factor), TPO (thrombopoietin) or IL-3, all of which depend on RAS signaling, induce dose-dependent expression of Anamorsin in mouse cells.
Reactivity
Human, Mouse
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
CIAPIN1 protein structure - BS8142 shown in red.