BS6781

antibody from Bioworld Technology, Inc
Targeting: SLC22A6 OAT1, PAHT, ROAT1
Provider product page for BS6781
Western blot
Immunohistochemistry

Antibody data

Product number
BS6781 - Provider product page
Provider
Bioworld Technology, Inc
Product name
SLC22A6 polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human SLC22A6.
Description
The organic anion transporter (OAT) family of proteins mediate the secretion of exogenous and endogenous levels of metabolites from tissues throughout the body. OAT1 (organic anion transporter 1), a 563 amino acid protein, and OAT3 (organic anion transporter 3), a 542 amino acid protein, are two members of the OAT family and are highly expressed in kidneys. Localized specifically to the basolateral membrane, OAT1 and OAT3 are involved in the elimination of toxic organic anions, such as benzylpenicillin and cimetidine, from proximal renal tubules. Via their ability to remove anions from renal tissues, OAT1 and OAT3 are able to regulate the amount of toxins within the kidneys. Additionally, OAT1 functions as an organic anion exchanger that couples the uptake of one organic anion molecule with the efflux of one endogenous levels of dicarboxylic acid molecule, such as ketoglutarate. Four isoforms of OAT1 and three isoforms of OAT3 are expressed due to alternative splicing events.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
SLC22A6 protein structure - BS6781 shown in red.