26574-1-AP

antibody from Proteintech Group

Targeting: SLC22A6 OAT1, PAHT, ROAT1

Western blot (Data presented on provider website)

ELISA (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

26574-1-AP

Provider

Proteintech Group

Product name

OAT1 antibody

Antibody type

Polyclonal

Description

OAT1 antibody (Cat. #26574-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IHC, WB,ELISA.

Reactivity

Human, Mouse

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

20ul, 150ul

References

Submitted references

Metabolic Communication by SGLT2 Inhibition.

Billing AM, Kim YC, Gullaksen S, Schrage B, Raabe J, Hutzfeldt A, Demir F, Kovalenko E, Lassé M, Dugourd A, Fallegger R, Klampe B, Jaegers J, Li Q, Kravtsova O, Crespo-Masip M, Palermo A, Fenton RA, Hoxha E, Blankenberg S, Kirchhof P, Huber TB, Laugesen E, Zeller T, Chrysopoulou M, Saez-Rodriguez J, Magnussen C, Eschenhagen T, Staruschenko A, Siuzdak G, Poulsen PL, Schwab C, Cuello F, Vallon V, Rinschen MM
Circulation 2024 Mar 12;149(11):860-884

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Analyzing chemical composition of Sargentodoxae caulis water extract and their hypouricemia effect in hyperuricemic mice.

Liu WW, Dong HJ, Zhang Z, Ma XH, Liu S, Huang W, Wang X
Fitoterapia 2024 Jun;175:105926

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Fuling-Zexie formula attenuates hyperuricemia-induced nephropathy and inhibits JAK2/STAT3 signaling and NLRP3 inflammasome activation in mice.

Lu M, Yin J, Xu T, Dai X, Liu T, Zhang Y, Wang S, Liu Y, Shi H, Zhang Y, Mo F, Sukhorukov V, Orekhov AN, Gao S, Wang L, Zhang D
Journal of ethnopharmacology 2024 Jan 30;319(Pt 2):117262

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Data mining-guided alleviation of hyperuricemia by Paeonia veitchii Lynch through inhibition of xanthine oxidase and regulation of renal urate transporters.

Du J, Wang N, Yu D, He P, Gao Y, Tu Y, Li Y
Phytomedicine : international journal of phytotherapy and phytopharmacology 2024 Feb;124:155305

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SGLT2 inhibitor dapagliflozin protects the kidney in a murine model of Balkan nephropathy.

Oe Y, Kim YC, Sidorenko VS, Zhang H, Kanoo S, Lopez N, Goodluck HA, Crespo-Masip M, Vallon V
American journal of physiology. Renal physiology 2024 Feb 1;326(2):F227-F240

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Paeonia × suffruticosa Andrews leaf extract and its main component apigenin 7-O-glucoside ameliorate hyperuricemia by inhibiting xanthine oxidase activity and regulating renal urate transporters.

Zhang Y, Li Y, Li C, Zhao Y, Xu L, Ma S, Lin F, Xie Y, An J, Wang S
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Sep;118:154957

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Amelioration effects of α-viniferin on hyperuricemia and hyperuricemia-induced kidney injury in mice.

Guo XL, Gao YY, Yang YX, Zhu QF, Guan HY, He X, Zhang CL, Wang Y, Xu GB, Zou SH, Wei MC, Zhang J, Zhang JJ, Liao SG
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Jul 25;116:154868

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Inhibition of Transforming Growth Factor-β Improves Primary Renal Tubule Cell Differentiation in Long-Term Culture.

Hunter K, Larsen JA, Love HD, Evans RC, Roy S, Zent R, Harris RC, Wilson MH, Fissell WH
Tissue engineering. Part A 2023 Feb;29(3-4):102-111

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Sanghuangporus vaninii ethanol extract alleviates hyperuricemic renal injury by regulating the uric acid transporters and inhibiting HK-2 apoptosis.

Hua L, Zhang S, Yang J, Zhou X, Shi S
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2023 Aug;164:114970

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Simiao San alleviates hyperuricemia and kidney inflammation by inhibiting NLRP3 inflammasome and JAK2/STAT3 signaling in hyperuricemia mice.

Zhang Y, Wang S, Dai X, Liu T, Liu Y, Shi H, Yin J, Xu T, Zhang Y, Zhao D, Sukhorukov V, Orekhov AN, Gao S, Wang L, Zhang D
Journal of ethnopharmacology 2023 Aug 10;312:116530

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Therapeutic effects and mechanisms of N-(9,10-anthraquinone-2-ylcarbonyl) xanthine oxidase inhibitors on hyperuricemia.

Gao T, Xu J, Xiao Y, Li J, Hu W, Su X, Shen X, Yu W, Chen Z, Huang B, Li H, Wang X
Frontiers in pharmacology 2022;13:950699

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Apigenin Ameliorates Hyperuricemia and Renal Injury through Regulation of Uric Acid Metabolism and JAK2/STAT3 Signaling Pathway.

Liu T, Gao H, Zhang Y, Wang S, Lu M, Dai X, Liu Y, Shi H, Xu T, Yin J, Gao S, Wang L, Zhang D
Pharmaceuticals (Basel, Switzerland) 2022 Nov 21;15(11)

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Withaferin A protects against hyperuricemia induced kidney injury and its possible mechanisms.

Zhao X, Wang J, Tang L, Li P, Ru J, Bai Y
Bioengineered 2021 Dec;12(1):589-600

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Berberrubine attenuates potassium oxonate- and hypoxanthine-induced hyperuricemia by regulating urate transporters and JAK2/STAT3 signaling pathway.

Lin G, Yu Q, Xu L, Huang Z, Mai L, Jiang L, Su Z, Xie J, Li Y, Liu Y, Lin Z, Chen J
European journal of pharmacology 2021 Dec 5;912:174592

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Active components from Lagotis brachystachya maintain uric acid homeostasis by inhibiting renal TLR4-NLRP3 signaling in hyperuricemic mice.

Zhu JX, Yang HY, Hu WQ, Cheng J, Liu Y, Yi LT, Cheng HY
Inflammopharmacology 2021 Aug;29(4):1187-1200