BS6964

antibody from Bioworld Technology, Inc
Targeting: HLA-DPB1 HLA-DP1B
Provider product page for BS6964
Western blot
Immunohistochemistry

Antibody data

Product number
BS6964 - Provider product page
Provider
Bioworld Technology, Inc
Product name
HLA DPB1 polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human HLA-DPB1.
Description
HLA-DPB belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DPA) and a beta chain (DPB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail. Within the DP molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to 4 different molecules.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
HLA-DPB1 protein structure - BS6964 shown in red.