POLR2C

This gene encodes the third largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. The product of this gene contains a cysteine rich region and exists as a heterodimer with another polymerase subunit, POLR2J. These two subunits form a core subassembly unit of the polymerase. A pseudogene has been identified on chromosome 21. [provided by RefSeq, Jul 2008]

Description

RNA polymerase II subunit C

Tissue specificity

Low tissue specificity

Subcell location

Nucleoplasm, Cytosol

Predicted location

Intracellular

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Metabolic proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)
RNA polymerase related proteins

Chromosome

16:q21 (57462660 - 57472009)

Ensembl ID

ENSG00000102978  (ver. 103.38)

Orthologs

Mouse Polr2c: ENSMUSG00000031783

UniProt

P19387

neXtProt

NX_P19387

Human splice variants
Mouse splice variants