Antibody data
- Antibody Data
- Antigen structure
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- Product number
- 328212 - Provider product page
- Provider
- BioLegend
- Proper citation
- BioLegend Cat#328212, RRID:AB_2099950
- Product name
- PE/Cy7 anti-human CD39
- Antibody type
- Monoclonal
- Antigen
- PHA activated human lymphocytes
- Description
- Human CD39 is an integral membrane protein with two transmembrane domains and exists as a homotetramer. Expression of CD39 is found on activated lymphocytes, a subset of T cells and B cells, and dendritic cells with weak staining on monocytes and granulocytes. Recently, CD39 and CD73 have been found on regulatory T cells, specifically the effector/memory like T cells. CD39 can hydrolyze both nucleoside triphosphates and diphosphates. CD39 is the dominant ecto nucleotidase of vascular and placental trophoblastic tissues and appears to modulate the functional expression of type 2 purinergic (P2) G protein coupled receptors (GPCRs). CD39 has intrinsic ecto-ATPase activity. Expression of CD39 is induced on T cells and increased on B cells as a late activation antigen.
- Reactivity
- Human, Simian
- Host
- Mouse
- Conjugate
- Infrared dye
- Isotype
- IgG
- Vial size
- 100 tests
- Storage
- The antibody solution should be stored undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
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