RA0212

antibody from Oursmab

Targeting: ENTPD1 ATPDase, CD39, NTPDase-1, SPG64

Western blot (Data presented on provider website)

ELISA (Recommended by provider)

Immunocytochemistry (Recommended by provider)

Flow cytometry (Recommended by provider)

Functional assay (Recommended by provider)

Antibody Data

Product number

RA0212

Provider

Oursmab

Product name

Eurestobart (Biosimilar Reference Antibody) (ENTPD1)

Antibody type

Monoclonal

Description

Eurestobart is an investigational, humanized immunoglobulin G1 kappa (IgG1¦Ê) monoclonal antibody being developed for potential applications in oncology and immunomodulation. It functions as a targeted inhibitor of ectonucleoside triphosphate diphosphohydrolase activity, specifically by binding to a member of the ENTPDase family (also known as CD39 family). By binding to its target ENTPDase, this antibody is designed to modulate the extracellular purinergic signaling pathway. This modulation primarily affects the conversion of pro-inflammatory extracellular ATP (eATP) into immunosuppressive adenosine, thereby aiming to shift the balance in the tumor microenvironment or inflammatory sites from an immunosuppressive state towards a more immunostimulatory one.

Reactivity

Human

Isotype

IgG

Vial size

100 ¦Ìg,1 mg,5 mg,10 mg,25 mg,50 mg,100 mg

Concentration

Bottled at the concentration indicated on the vial.

Storage

Store at -20¡ãC or -80¡ãC. Avoid repeated freeze.