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- References [11]
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- Validations
- Western blot [1]
- Immunocytochemistry [1]
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- Product number
- 22167-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#22167-1-AP, RRID:AB_10949193
- Product name
- IQGAP1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated IQGAP1 antibody (Cat. #22167-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Targeting NRAS via miR-1304-5p or farnesyltransferase inhibition confers sensitivity to ALK inhibitors in ALK-mutant neuroblastoma.
Glutamine metabolic microenvironment drives M2 macrophage polarization to mediate trastuzumab resistance in HER2-positive gastric cancer.
Tension of plus-end tracking protein Clip170 confers directionality and aggressiveness during breast cancer migration.
Multiomic analysis of papillary thyroid cancers identifies BAIAP2L1-BRAF fusion and requirement of TRIM25, PDE5A and PKCĪ“ for tumorigenesis.
Comprehensive analysis of the expression and prognosis for IQ motif-containing GTPase-activating proteins in hepatocellular carcinoma.
Anti-allergic drug azelastine suppresses colon tumorigenesis by directly targeting ARF1 to inhibit IQGAP1-ERK-Drp1-mediated mitochondrial fission.
The scaffold protein IQGAP1 links heat-induced stress signals to alternative splicing regulation in gastric cancer cells.
MAL2 interacts with IQGAP1 to promote pancreatic cancer progression by increasing ERK1/2 phosphorylation.
Circadian locomotor output cycles kaput affects the proliferation and migration of breast cancer cells by regulating the expression of E-cadherin via IQ motif containing GTPase activating protein 1.
IQGAP1 Mediates Hcp1-Promoted Escherichia coli Meningitis by Stimulating the MAPK Pathway.
Diet-induced hypercholesterolemia promotes androgen-independent prostate cancer metastasis via IQGAP1 and caveolin-1.
Pucci P, Lee LC, Han M, Matthews JD, Jahangiri L, Schlederer M, Manners E, Sorby-Adams A, Kaggie J, Trigg RM, Steel C, Hare L, James ER, Prokoph N, Ducray SP, Merkel O, Rifatbegovic F, Luo J, Taschner-Mandl S, Kenner L, Burke GAA, Turner SD
Nature communications 2024 Apr 23;15(1):3422
Nature communications 2024 Apr 23;15(1):3422
Glutamine metabolic microenvironment drives M2 macrophage polarization to mediate trastuzumab resistance in HER2-positive gastric cancer.
Hu X, Ma Z, Xu B, Li S, Yao Z, Liang B, Wang J, Liao W, Lin L, Wang C, Zheng S, Wu Q, Huang Q, Yu L, Wang F, Shi M
Cancer communications (London, England) 2023 Aug;43(8):909-937
Cancer communications (London, England) 2023 Aug;43(8):909-937
Tension of plus-end tracking protein Clip170 confers directionality and aggressiveness during breast cancer migration.
Hu Y, Xie Q, Wu X, Liu W, Li D, Li C, Zhao W, Chen L, Zheng Z, Li G, Guo J
Cell death & disease 2022 Oct 8;13(10):856
Cell death & disease 2022 Oct 8;13(10):856
Multiomic analysis of papillary thyroid cancers identifies BAIAP2L1-BRAF fusion and requirement of TRIM25, PDE5A and PKCĪ“ for tumorigenesis.
Renaud E, Riegel K, Romero R, Suryamohan K, Distler U, Tenzer S, Schad A, Musholt TJ, Rajalingam K
Molecular cancer 2022 Oct 10;21(1):195
Molecular cancer 2022 Oct 10;21(1):195
Comprehensive analysis of the expression and prognosis for IQ motif-containing GTPase-activating proteins in hepatocellular carcinoma.
Dai Q, Song F, Li X, Huang F, Zhao H
BMC cancer 2022 Nov 1;22(1):1121
BMC cancer 2022 Nov 1;22(1):1121
Anti-allergic drug azelastine suppresses colon tumorigenesis by directly targeting ARF1 to inhibit IQGAP1-ERK-Drp1-mediated mitochondrial fission.
Hu HF, Xu WW, Li YJ, He Y, Zhang WX, Liao L, Zhang QH, Han L, Yin XF, Zhao XX, Pan YL, Li B, He QY
Theranostics 2021;11(4):1828-1844
Theranostics 2021;11(4):1828-1844
The scaffold protein IQGAP1 links heat-induced stress signals to alternative splicing regulation in gastric cancer cells.
Birladeanu AM, Rogalska M, Potiri M, Papadaki V, Andreadou M, Kontoyiannis DL, Lewis JD, Erpapazoglou Z, Kafasla P
Oncogene 2021 Sep;40(36):5518-5532
Oncogene 2021 Sep;40(36):5518-5532
MAL2 interacts with IQGAP1 to promote pancreatic cancer progression by increasing ERK1/2 phosphorylation.
Zhang B, Xiao J, Cheng X, Liu T
Biochemical and biophysical research communications 2021 May 21;554:63-70
Biochemical and biophysical research communications 2021 May 21;554:63-70
Circadian locomotor output cycles kaput affects the proliferation and migration of breast cancer cells by regulating the expression of E-cadherin via IQ motif containing GTPase activating protein 1.
Li X, Wang S, Yang S, Ying J, Yu H, Yang C, Liu Y, Wang Y, Cheng S, Xiao J, Guo H, Jiang Z, Wang Z
Oncology letters 2018 May;15(5):7097-7103
Oncology letters 2018 May;15(5):7097-7103
IQGAP1 Mediates Hcp1-Promoted Escherichia coli Meningitis by Stimulating the MAPK Pathway.
Zhao M, Zhang L, Lv S, Zhang C, Wang L, Chen H, Zhou Y, Lou J
Frontiers in cellular and infection microbiology 2017;7:132
Frontiers in cellular and infection microbiology 2017;7:132
Diet-induced hypercholesterolemia promotes androgen-independent prostate cancer metastasis via IQGAP1 and caveolin-1.
Moon H, Ruelcke JE, Choi E, Sharpe LJ, Nassar ZD, Bielefeldt-Ohmann H, Parat MO, Shah A, Francois M, Inder KL, Brown AJ, Russell PJ, Parton RG, Hill MM
Oncotarget 2015 Apr 10;6(10):7438-53
Oncotarget 2015 Apr 10;6(10):7438-53
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HeLa cells were subjected to SDS PAGE followed by western blot with 22167-1-AP(IQGAP1 antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The IQGAP1 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human IQGAP1. This antibody recognizes human,mouse,rat antigen. The IQGAP1 antibody has been validated for the following applications: ELISA, WB, IHC, IF analysis.
