Antibody data
- Antibody Data
- Antigen structure
- References [6]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
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Validation data
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- Product number
- 22167-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#22167-1-AP, RRID:AB_10949193
- Product name
- IQGAP1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated IQGAP1 antibody (Cat. #22167-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Anti-allergic drug azelastine suppresses colon tumorigenesis by directly targeting ARF1 to inhibit IQGAP1-ERK-Drp1-mediated mitochondrial fission.
The scaffold protein IQGAP1 links heat-induced stress signals to alternative splicing regulation in gastric cancer cells.
MAL2 interacts with IQGAP1 to promote pancreatic cancer progression by increasing ERK1/2 phosphorylation.
Circadian locomotor output cycles kaput affects the proliferation and migration of breast cancer cells by regulating the expression of E-cadherin via IQ motif containing GTPase activating protein 1.
IQGAP1 Mediates Hcp1-Promoted Escherichia coli Meningitis by Stimulating the MAPK Pathway.
Diet-induced hypercholesterolemia promotes androgen-independent prostate cancer metastasis via IQGAP1 and caveolin-1.
Hu HF, Xu WW, Li YJ, He Y, Zhang WX, Liao L, Zhang QH, Han L, Yin XF, Zhao XX, Pan YL, Li B, He QY
Theranostics 2021;11(4):1828-1844
Theranostics 2021;11(4):1828-1844
The scaffold protein IQGAP1 links heat-induced stress signals to alternative splicing regulation in gastric cancer cells.
Birladeanu AM, Rogalska M, Potiri M, Papadaki V, Andreadou M, Kontoyiannis DL, Lewis JD, Erpapazoglou Z, Kafasla P
Oncogene 2021 Sep;40(36):5518-5532
Oncogene 2021 Sep;40(36):5518-5532
MAL2 interacts with IQGAP1 to promote pancreatic cancer progression by increasing ERK1/2 phosphorylation.
Zhang B, Xiao J, Cheng X, Liu T
Biochemical and biophysical research communications 2021 May 21;554:63-70
Biochemical and biophysical research communications 2021 May 21;554:63-70
Circadian locomotor output cycles kaput affects the proliferation and migration of breast cancer cells by regulating the expression of E-cadherin via IQ motif containing GTPase activating protein 1.
Li X, Wang S, Yang S, Ying J, Yu H, Yang C, Liu Y, Wang Y, Cheng S, Xiao J, Guo H, Jiang Z, Wang Z
Oncology letters 2018 May;15(5):7097-7103
Oncology letters 2018 May;15(5):7097-7103
IQGAP1 Mediates Hcp1-Promoted Escherichia coli Meningitis by Stimulating the MAPK Pathway.
Zhao M, Zhang L, Lv S, Zhang C, Wang L, Chen H, Zhou Y, Lou J
Frontiers in cellular and infection microbiology 2017;7:132
Frontiers in cellular and infection microbiology 2017;7:132
Diet-induced hypercholesterolemia promotes androgen-independent prostate cancer metastasis via IQGAP1 and caveolin-1.
Moon H, Ruelcke JE, Choi E, Sharpe LJ, Nassar ZD, Bielefeldt-Ohmann H, Parat MO, Shah A, Francois M, Inder KL, Brown AJ, Russell PJ, Parton RG, Hill MM
Oncotarget 2015 Apr 10;6(10):7438-53
Oncotarget 2015 Apr 10;6(10):7438-53
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HeLa cells were subjected to SDS PAGE followed by western blot with 22167-1-AP(IQGAP1 antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The IQGAP1 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human IQGAP1. This antibody recognizes human,mouse,rat antigen. The IQGAP1 antibody has been validated for the following applications: ELISA, WB, IHC, IF analysis.