Antibody data
- Antibody Data
- Antigen structure
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- Product number
- AMM02583G - Provider product page
- Provider
- Leading Biology
- Product name
- Retinoid X Receptor, β-Isotype Antibody
- Antibody type
- Monoclonal
- Description
- Retinoic acid (RA; active metabolite of vitamin A) plays a prominent role in regulating the transition of proliferating precursor cells (such as carcinoma cells and neuronal precursors) to postmitotic differentiated cells (Joshi et al., 2005). The retinoid X receptors (RXRs) family (RXRα, β and γ), preferentially bind 9-cis-RA and regulate gene transcription by forming heterodimers with a second family of RA receptors. RAs have been suggested to potentially play a therapeutic role in cervical cancer (Abu et al., 2005). RAs are known to play key roles in neuronal development and an increasing body of evidence indicates that retinoid signaling may regulate synaptic plasticity and associated learning and memory behaviors (Lane and Bailey, 2005).
- Reactivity
- Mouse, Rat
- Host
- Mouse
- Isotype
- IgG
- Antibody clone number
- 147
- Storage
- Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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