Antibody data
- Antibody Data
- Antigen structure
- References [13]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- 13921-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#13921-1-AP, RRID:AB_1851479
- Product name
- NKX2-5 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated NKX2-5 antibody (Cat. #13921-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IHC, WB, ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references D-galactose causes sinoatrial node dysfunction: from phenotype to mechanism.
LncCMRR Plays an Important Role in Cardiac Differentiation by Regulating the Purb/Flk1 Axis.
Super-enhancer-driven lncRNA Snhg7 aggravates cardiac hypertrophy via Tbx5/GLS2/ferroptosis axis.
NRF-2/HO-1 Pathway-Mediated SHOX2 Activation Is a Key Switch for Heart Rate Acceleration by Yixin-Fumai Granules.
A dual SHOX2:GFP; MYH6:mCherry knockin hESC reporter line for derivation of human SAN-like cells.
H3K9me2 regulates early transcription factors to promote mesenchymal stem‑cell differentiation into cardiomyocytes.
Homocysteine downregulates cardiac homeobox transcription factor NKX2.5 via IGFBP5.
Nkx2-5 Regulates the Proliferation and Migration of H9c2 Cells.
Placental P-glycoprotein inhibition enhances susceptibility to Di-(2-ethylhexyl)-phthalate induced cardiac malformations in mice: A possibly promising target for congenital heart defects prevention.
SDF-1α promotes repair of myocardial ischemic necrosis zones in rats.
Role of Nkx2.5 in H(2)O(2)-induced Nsd1 suppression.
The effect of maternal exposure to di-(2-ethylhexyl)-phthalate on fetal cardiac development in mice.
Post-transcriptional Regulation of Nkx2-5 by RHAU in Heart Development.
Zhang H, Chen C, Liu Y, Chen W, Qi J, Xu Y, Ren L, Yang G, Min D, Liu Z, Cai X, Hao M, Xu G, Hou P
Aging 2023 Nov 9;15(21):12551-12569
Aging 2023 Nov 9;15(21):12551-12569
LncCMRR Plays an Important Role in Cardiac Differentiation by Regulating the Purb/Flk1 Axis.
Yang Y, Wang X, Tan Y, Xu Y, Guo X, Wu Y, Wang W, Jing R, Zhu F, Ye D, Zhang Q, Lu C, Kang J, Wang G
Stem cells (Dayton, Ohio) 2023 Jan 30;41(1):11-25
Stem cells (Dayton, Ohio) 2023 Jan 30;41(1):11-25
Super-enhancer-driven lncRNA Snhg7 aggravates cardiac hypertrophy via Tbx5/GLS2/ferroptosis axis.
Zhang Q, Song C, Zhang M, Liu Y, Wang L, Xie Y, Qi H, Ba L, Shi P, Cao Y, Sun H
European journal of pharmacology 2023 Aug 15;953:175822
European journal of pharmacology 2023 Aug 15;953:175822
NRF-2/HO-1 Pathway-Mediated SHOX2 Activation Is a Key Switch for Heart Rate Acceleration by Yixin-Fumai Granules.
Zhang H, Chen C, Liu Y, Ren L, Qi J, Yang Y, Chen W, Yao Y, Cai X, Liu Z, Hao M, Li L, Deng Z, Sun M, Lu Y, Chen K, Hou P
Oxidative medicine and cellular longevity 2022;2022:8488269
Oxidative medicine and cellular longevity 2022;2022:8488269
A dual SHOX2:GFP; MYH6:mCherry knockin hESC reporter line for derivation of human SAN-like cells.
Ghazizadeh Z, Zhu J, Fattahi F, Tang A, Sun X, Amin S, Tsai SY, Khalaj M, Zhou T, Samuel RM, Zhang T, Ortega FA, Gordillo M, Moroziewicz D, NYSCF Global Stem Cell Array® Team, Paull D, Noggle SA, Xiang JZ, Studer L, Christini DJ, Pitt GS, Evans T, Chen S
iScience 2022 Apr 15;25(4):104153
iScience 2022 Apr 15;25(4):104153
H3K9me2 regulates early transcription factors to promote mesenchymal stem‑cell differentiation into cardiomyocytes.
Sun X, Gu X, Li H, Xu P, Li M, Zhu Y, Zuo Q, Li B
Molecular medicine reports 2021 Aug;24(2)
Molecular medicine reports 2021 Aug;24(2)
Homocysteine downregulates cardiac homeobox transcription factor NKX2.5 via IGFBP5.
Lai G, Wang L, Li Z, Zhao Y
American journal of physiology. Heart and circulatory physiology 2020 Dec 1;319(6):H1380-H1386
American journal of physiology. Heart and circulatory physiology 2020 Dec 1;319(6):H1380-H1386
Nkx2-5 Regulates the Proliferation and Migration of H9c2 Cells.
Wang H, Liu Y, Han S, Zi Y, Zhang Y, Kong R, Liu Z, Cai Z, Zhong C, Liu W, Li L, Jiang L
Medical science monitor : international medical journal of experimental and clinical research 2020 Aug 11;26:e925388
Medical science monitor : international medical journal of experimental and clinical research 2020 Aug 11;26:e925388
Placental P-glycoprotein inhibition enhances susceptibility to Di-(2-ethylhexyl)-phthalate induced cardiac malformations in mice: A possibly promising target for congenital heart defects prevention.
Tang C, Luo C, Hua Y, Zhou K, Duan H, Ma F, Zhang Y, Li Y, Qiu D, Wang C
PloS one 2019;14(5):e0214873
PloS one 2019;14(5):e0214873
SDF-1α promotes repair of myocardial ischemic necrosis zones in rats.
Cai X, Zhu Z, Zhang Y, Tian X
International journal of clinical and experimental pathology 2019;12(6):1956-1967
International journal of clinical and experimental pathology 2019;12(6):1956-1967
Role of Nkx2.5 in H(2)O(2)-induced Nsd1 suppression.
Liang X, Chu G, Wang L, Lai G, Zhao Y
Cell stress & chaperones 2019 Jul;24(4):697-707
Cell stress & chaperones 2019 Jul;24(4):697-707
The effect of maternal exposure to di-(2-ethylhexyl)-phthalate on fetal cardiac development in mice.
Tang C, Deng Y, Duan H, Zhang Y, Li Y, Qiu D, Zhou K, Hua Y, Wang C
Journal of applied toxicology : JAT 2018 Jun;38(6):834-842
Journal of applied toxicology : JAT 2018 Jun;38(6):834-842
Post-transcriptional Regulation of Nkx2-5 by RHAU in Heart Development.
Nie J, Jiang M, Zhang X, Tang H, Jin H, Huang X, Yuan B, Zhang C, Lai JC, Nagamine Y, Pan D, Wang W, Yang Z
Cell reports 2015 Oct 27;13(4):723-732
Cell reports 2015 Oct 27;13(4):723-732
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- human heart tissue were subjected to SDS PAGE followed by western blot with 13921-1-AP(NKX2-5 antibody) at dilution of 1:1200
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The NKX2-5 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human NKX2-5. This antibody recognizes human antigen. The NKX2-5 antibody has been validated for the following applications: ELISA, WB, IHC analysis.