FNab08184

antibody from FineTest Biotech
Targeting: SPO11 CT35, SPATA43, TOPVIA
Provider product page for FNab08184
Western blot
ELISA

Antibody data

Product number
FNab08184 - Provider product page
Provider
FineTest Biotech
Product name
SPO11 antibody
Antibody type
Polyclonal
Antigen
Recombinant protein fragment
Description
Component of a topoisomerase 6 complex specifically required for meiotic recombination. Together with TOP6BL, mediates DNA cleavage that forms the double-strand breaks(DSB) that initiate meiotic recombination. The complex promotes relaxation of negative and positive supercoiled DNA and DNA decatenation through cleavage and ligation cycles. Essential for the phosphorylation of SMC3, HORMAD1 and HORMAD2.
Reactivity
Human, Mouse
Host
Rabbit
Conjugate
Unconjugated
Antigen sequence
SPO11 meiotic protein covalently bo
und to DSB homolog
Epitope
IgG
Isotype
IgG
Vial size
100¦Ìg
Concentration
Immunogen affinity purified
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
Handling
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
SPO11 protein structure - FNab08184 shown in red.