CABT-B9209
antibody from Creative Diagnostics
Targeting: FKBP10
FKBP6, FKBP65, FLJ20683, FLJ22041, FLJ23833, hFKBP65
Antibody data
- Antibody Data
- Antigen structure
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- Validations [0]
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- Product number
- CABT-B9209 - Provider product page
- Provider
- Creative Diagnostics
- Product name
- Mouse anti-Mouse FKBP65 monoclonal antibody, clone 36/GLCQ76
- Antibody type
- Monoclonal
- Description
- FK506, one of multiple potent compounds that block T cell proliferation, is used for immunosuppressive therapy. Several FK506-binding proteins (FKBPs) have been identified in the search for intracellular targets for FK506. These include FKBP12, FKBP13, FKBP51, and FKBP52. The immunosuppressive effects of FK506 and FKBPs result from the inhibition of the calcineurin phosphatase, a well known component of the signaling cascade leading to IL-2 production. FKBP65 is another member of the FKBP protein family and contains the characteristic peptidylprolyl cis-trans-isomerase activity. FKBP65 has been reported to be expressed in the lung, testis, brain, heart, and spleen. Although it has a predicted molecular weight of 65 kDa, FKBP65 has been observed to migrate ranging from 68-72 kDa in SDS electrophoresis gels, perhaps, due to glycosylation and/or phosphorylation.
- Reactivity
- Human, Mouse, Rat
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- 36/GLCQ76
- Vial size
- 50 _g
- Concentration
- 250 Ã×g/ml
- Storage
- Store undiluted at -20°C.
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