60063-1-Ig

antibody from Proteintech Group

Targeting: STC2 STC-2

Western blot (Supportive data in Antibodypedia)

ELISA (Data presented on provider website)

Immunocytochemistry (Supportive data in Antibodypedia)

Immunohistochemistry (Supportive data in Antibodypedia)

Antibody Data

Product number

60063-1-Ig

Provider

Proteintech Group

Proper citation

Proteintech Cat#60063-1-Ig, RRID:AB_2197544

Product name

Stanniocalcin 2 antibody

Antibody type

Monoclonal

Description

KD/KO validated Stanniocalcin 2 antibody (Cat. #60063-1-Ig) is a mouse monoclonal antibody that shows reactivity with human, mouse, pig and has been validated for the following applications: IF, IHC, WB,ELISA.

Reactivity

Human, Mouse, Porcine

Host

Mouse

Conjugate

Unconjugated

Isotype

IgG

Antibody clone number

4H1E7

Vial size

20ul, 150ul

References

Submitted references

Smoking-Induced STC2(+) Tumor Cells Drive Tumor-Vascular Crosstalk in Laryngeal Squamous Cell Carcinoma via Spatial and Single-Cell Transcriptomics.

Shen Y, Gao L, Huang Q, Zhou L, Xu C, Wu C
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2026 Jan;13(5):e11932

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A novel identified epithelial ligand-receptor-associated gene signature highlights POPDC3 as a potential therapy target for non-small cell lung cancer.

Zhu XR, Zhu JQ, Gu QH, Liu N, Lu JJ, Li XH, Liu YY, Zheng X, Chen MB, Ji Y
Cell death & disease 2025 Feb 19;16(1):114

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STC2 Serves as a Critical Hypoxic Effector in Keloid Pathogenesis by Orchestrating Fibroblasts Activation and ECM Remodelling.

Qian L, Deng S, Tian T, He Y, Li Y, Wang X, Tian T, Jiang M, Pan Y, Li D
Experimental dermatology 2025 Dec;34(12):e70193

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FUT3 mediated GRP78 fucosylation promotes colorectal cancer survival and proliferation under glucose restriction via PERK/ATF4/STC2 axis.

Qin K, Zhang H, Shi Y, Wu R, Wu C, Wu Y, He C, Han Z, Luo Y, Fang Y, Yan X, Wang X, Li M, Li A, Liu S, Li Q
NPJ precision oncology 2025 Dec 14;10(1):19

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STC2 knockdown inhibits cell proliferation and glycolysis in hepatocellular carcinoma through promoting autophagy by PI3K/Akt/mTOR pathway.

Li D, Xiong Y, Li M, Long L, Zhang Y, Yan H, Xiang H
Archives of biochemistry and biophysics 2024 Nov;761:110149

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Osteosarcoma transcriptome data exploration reveals STC2 as a novel risk indicator in disease progression.

Wang Z, Zeng Z, Gao F, Gui Z, Du J, Shen N, Shang Y, Yang Z, Shang L, Wei R, Ma W, Wang C
BMC medical genomics 2023 Feb 20;16(1):30

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The Oncogenic and Diagnostic Potential of Stanniocalcin 2 in Hepatocellular Carcinoma.

Wu Z, Cheng H, Liu J, Zhang S, Zhang M, Liu F, Li Y, Huang Q, Jiang Y, Chen S, Lv L, Li D, Zeng JZ
Journal of hepatocellular carcinoma 2022;9:141-155

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The novel prognostic risk factor STC2 can regulate the occurrence and progression of osteosarcoma via the glycolytic pathway.

Yu B, Zhang F, Liu L, Liang Y, Tang X, Peng Y, Cai F, Zeng D, Yuan X, Li J, Guo Y, Lv B, Wang M, Liao Q, Lv XB
Biochemical and biophysical research communications 2021 May 21;554:25-32

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STC2 Is a Potential Prognostic Biomarker for Pancreatic Cancer and Promotes Migration and Invasion by Inducing Epithelial-Mesenchymal Transition.

Lin C, Sun L, Huang S, Weng X, Wu Z
BioMed research international 2019;2019:8042489

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Profiling the Gene Expression and DNA Methylation in the Mouse Brain after Ischemic Preconditioning.

Cai M, Zhu Y, Li Z, Josephs-Spaulding J, Zhou Y, Hu Y, Chen H, Liu Y, He W, Zhang J
Neuroscience 2019 May 15;406:249-261

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STC2 promotes head and neck squamous cell carcinoma metastasis through modulating the PI3K/AKT/Snail signaling.

Yang S, Ji Q, Chang B, Wang Y, Zhu Y, Li D, Huang C, Wang Y, Sun G, Zhang L, Guan Q, Xiang J, Wei W, Lu Z, Liao T, Meng J, Wang Z, Ma B, Zhou L, Wang Y, Yang G
Oncotarget 2017 Jan 24;8(4):5976-5991

Western blot

Supportive validation

Submitted by

Proteintech Group (provider)

Main image

Experimental details

HEK-293 cells were subjected to SDS PAGE followed by western blot with 60063-1-Ig(STC2 antibody) at dilution of 1:1000

Sample type

cell line

Immunocytochemistry

Supportive validation

Submitted by

Proteintech Group (provider)

Main image

Experimental details

Immunofluorescent analysis of Hela cells, using STC2 antibody 60063-1-lg at 1:25 dilution and Rhodamine-labeled goat anti-mouse IgG (red). Blue pseudocolor = DAPI (fluorescent DNA dye).

Sample type

cell line

Immunohistochemistry

Supportive validation

Submitted by

Proteintech Group (provider)

Main image

Experimental details

Immunohistochemical of paraffin-embedded human breast cancer using 60063-1-Ig(STC2 antibody) at dilution of 1:50 (under 10x lens)

Sample type

tissue

Supportive validation

Submitted by

Proteintech Group (provider)

Main image

Experimental details

Immunohistochemical of paraffin-embedded human breast cancer using 60063-1-Ig(STC2 antibody) at dilution of 1:50 (under 40x lens)

Sample type

tissue