AF2830

antibody from R&D Systems

Targeting: STC2 STC-2

Western blot (Data presented on provider website)

Antibody Data

Product number

AF2830

Provider

R&D Systems

Product name

Human Stanniocalcin 2/STC-2 Antibody

Antibody type

Polyclonal

Description

Antigen Affinity-purified. Detects human and mouse Stanniocalcin 2/STC-2 in direct ELISAs and Western blots. In direct ELISAs, less than 5% cross-reactivity with recombinant human STC-1 is observed.

Reactivity

Human

Host

Goat

Conjugate

Unconjugated

Antigen sequence

O76061


Isotype

IgG

Vial size

100 ug

Concentration

LYOPH

Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.

References

Submitted references

Rare and low-frequency coding variants alter human adult height.

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Nature 2017 Feb 9;542(7640):186-190

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Stanniocalcin-1 Potently Inhibits the Proteolytic Activity of the Metalloproteinase Pregnancy-associated Plasma Protein-A.

Kløverpris S, Mikkelsen JH, Pedersen JH, Jepsen MR, Laursen LS, Petersen SV, Oxvig C
The Journal of biological chemistry 2015 Sep 4;290(36):21915-24

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Stanniocalcin-2 inhibits mammalian growth by proteolytic inhibition of the insulin-like growth factor axis.

Jepsen MR, Kløverpris S, Mikkelsen JH, Pedersen JH, Füchtbauer EM, Laursen LS, Oxvig C
The Journal of biological chemistry 2015 Feb 6;290(6):3430-9

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Survival analyses correlate stanniocalcin 2 overexpression to poor prognosis of nasopharyngeal carcinomas.

Lin S, Guo Q, Wen J, Li C, Lin J, Cui X, Sang N, Pan J
Journal of experimental & clinical cancer research : CR 2014 Mar 8;33:26