FNab06749

antibody from FineTest Biotech

Targeting: PRC1 ASE1

Western blot

ELISA

Immunohistochemistry

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Validation data

Product number: FNab06749 - Provider product page
Provider: FineTest Biotech
Product name: PRC1 antibody
Antibody type: Polyclonal
Antigen: Recombinant protein fragment
Description: Key regulator of cytokinesis that cross-links antiparrallel microtubules at an average distance of 35 nM. Essential for controlling the spatiotemporal formation of the midzone and successful cytokinesis. Required for KIF14 localization to the central spindle and midbody. Required to recruit PLK1 to the spindle. Stimulates PLK1 phosphorylation of RACGAP1 to allow recruitment of ECT2 to the central spindle. Acts as an oncogene for promoting bladder cancer cells proliferation, apoptosis inhibition and carcinogenic progression(PubMed:17409436).
Reactivity: Human
Host: Rabbit
Conjugate: Unconjugated
Antigen sequence: protein regulator of cytokinesis 1
Epitope: IgG
Isotype: IgG
Vial size: 100¦Ìg
Concentration: Immunogen affinity purified
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
Handling: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)

PRC1 protein structure - FNab06749 shown in red.