Antibody data
- Antibody Data
- Antigen structure
- References [12]
- Comments [0]
- Validations
- Western blot [2]
- Immunocytochemistry [1]
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Validation data
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- Product number
- 16921-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#16921-1-AP, RRID:AB_2290228
- Product name
- ATL3 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated ATL3 antibody (Cat. #16921-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Aurora kinase A-mediated phosphorylation triggers structural alteration of Rab1A to enhance ER complexity during mitosis.
Adaptive responses of neuronal cells to chronic endoplasmic reticulum (ER) stress.
Deficiency of Perry syndrome-associated p150(Glued) in midbrain dopaminergic neurons leads to progressive neurodegeneration and endoplasmic reticulum abnormalities.
Localization of Kif1c mRNA to cell protrusions dictates binding partner specificity of the encoded protein.
Heteromeric clusters of ubiquitinated ER-shaping proteins drive ER-phagy.
The atlastin ER morphogenic proteins promote formation of a membrane penetration site during non-enveloped virus entry.
Profiling of purified autophagic vesicle degradome in the maturing and aging brain.
ER proteins decipher the tubulin code to regulate organelle distribution.
ATL3 Is a Tubular ER-Phagy Receptor for GABARAP-Mediated Selective Autophagy.
Influenza A virus ribonucleoproteins form liquid organelles at endoplasmic reticulum exit sites.
DNA damage triggers tubular endoplasmic reticulum extension to promote apoptosis by facilitating ER-mitochondria signaling.
Efficient protein targeting to the inner nuclear membrane requires Atlastin-dependent maintenance of ER topology.
Zhang W, Zhang Z, Xiang Y, Gu DD, Chen J, Chen Y, Zhai S, Liu Y, Jiang T, Liu C, He B, Yan M, Wang Z, Xu J, Cao YL, Deng B, Zeng D, Lei J, Zhuo J, Lei X, Long Z, Jin B, Chen T, Li D, Shen Y, Hu J, Gao S, Liu Q
Nature structural & molecular biology 2024 Feb;31(2):219-231
Nature structural & molecular biology 2024 Feb;31(2):219-231
Adaptive responses of neuronal cells to chronic endoplasmic reticulum (ER) stress.
Pham TNM, Perumal N, Manicam C, Basoglu M, Eimer S, Fuhrmann DC, Pietrzik CU, Clement AM, Körschgen H, Schepers J, Behl C
Redox biology 2023 Nov;67:102943
Redox biology 2023 Nov;67:102943
Deficiency of Perry syndrome-associated p150(Glued) in midbrain dopaminergic neurons leads to progressive neurodegeneration and endoplasmic reticulum abnormalities.
Yu J, Yang X, Zheng J, Sgobio C, Sun L, Cai H
NPJ Parkinson's disease 2023 Mar 7;9(1):35
NPJ Parkinson's disease 2023 Mar 7;9(1):35
Localization of Kif1c mRNA to cell protrusions dictates binding partner specificity of the encoded protein.
Norris ML, Mendell JT
Genes & development 2023 Mar 1;37(5-6):191-203
Genes & development 2023 Mar 1;37(5-6):191-203
Heteromeric clusters of ubiquitinated ER-shaping proteins drive ER-phagy.
Foronda H, Fu Y, Covarrubias-Pinto A, Bocker HT, González A, Seemann E, Franzka P, Bock A, Bhaskara RM, Liebmann L, Hoffmann ME, Katona I, Koch N, Weis J, Kurth I, Gleeson JG, Reggiori F, Hummer G, Kessels MM, Qualmann B, Mari M, Dikić I, Hübner CA
Nature 2023 Jun;618(7964):402-410
Nature 2023 Jun;618(7964):402-410
The atlastin ER morphogenic proteins promote formation of a membrane penetration site during non-enveloped virus entry.
Pletan M, Liu X, Cha G, Chen YJ, Knupp J, Tsai B
Journal of virology 2023 Aug 31;97(8):e0075623
Journal of virology 2023 Aug 31;97(8):e0075623
Profiling of purified autophagic vesicle degradome in the maturing and aging brain.
Kallergi E, Siva Sankar D, Matera A, Kolaxi A, Paolicelli RC, Dengjel J, Nikoletopoulou V
Neuron 2023 Aug 2;111(15):2329-2347.e7
Neuron 2023 Aug 2;111(15):2329-2347.e7
ER proteins decipher the tubulin code to regulate organelle distribution.
Zheng P, Obara CJ, Szczesna E, Nixon-Abell J, Mahalingan KK, Roll-Mecak A, Lippincott-Schwartz J, Blackstone C
Nature 2022 Jan;601(7891):132-138
Nature 2022 Jan;601(7891):132-138
ATL3 Is a Tubular ER-Phagy Receptor for GABARAP-Mediated Selective Autophagy.
Chen Q, Xiao Y, Chai P, Zheng P, Teng J, Chen J
Current biology : CB 2019 Mar 4;29(5):846-855.e6
Current biology : CB 2019 Mar 4;29(5):846-855.e6
Influenza A virus ribonucleoproteins form liquid organelles at endoplasmic reticulum exit sites.
Alenquer M, Vale-Costa S, Etibor TA, Ferreira F, Sousa AL, Amorim MJ
Nature communications 2019 Apr 9;10(1):1629
Nature communications 2019 Apr 9;10(1):1629
DNA damage triggers tubular endoplasmic reticulum extension to promote apoptosis by facilitating ER-mitochondria signaling.
Zheng P, Chen Q, Tian X, Qian N, Chai P, Liu B, Hu J, Blackstone C, Zhu D, Teng J, Chen J
Cell research 2018 Aug;28(8):833-854
Cell research 2018 Aug;28(8):833-854
Efficient protein targeting to the inner nuclear membrane requires Atlastin-dependent maintenance of ER topology.
Pawar S, Ungricht R, Tiefenboeck P, Leroux JC, Kutay U
eLife 2017 Aug 14;6
eLife 2017 Aug 14;6
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Jurkat cells were subjected to SDS PAGE followed by western blot with 16921-1-AP( ATL3 Antibody) at dilution of 1:1500
- Sample type
- cell line
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- SMMC-7721 cells were subjected to SDS PAGE followed by western blot with 16921-1-AP( ATL3 Antibody) at dilution of 1:600
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of HepG2 cells, using ATL3 antibody 16921-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
- Sample type
- cell line