Antibody data
- Antibody Data
- Antigen structure
- References [9]
- Comments [0]
- Validations
- Immunoprecipitation [1]
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- Product number
- 24643-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- SORBS2 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated SORBS2 antibody (Cat. #24643-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IP, WB,ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references The RNA-binding protein sorbin and SH3 domain-containing 2 are transcriptionally regulated by specificity protein 1 and function as tumor suppressors in bladder cancer by stabilizing tissue factor pathway inhibitor.
Integrative multi-omic profiling of adult mouse brain endothelial cells and potential implications in Alzheimer's disease.
SORBS2 as a molecular target for atherosclerosis in patients with familial hypercholesterolemia.
The interaction protein of SORBS2 in myocardial tissue to find out the pathogenic mechanism of LVNC disease.
Oncogenic AURKA-enhanced N(6)-methyladenosine modification increases DROSHA mRNA stability to transactivate STC1 in breast cancer stem-like cells.
Musk ketone induces apoptosis of gastric cancer cells via downregulation of sorbin and SH3 domain containing 2.
Elevated myocardial SORBS2 and the underlying implications in left ventricular noncompaction cardiomyopathy.
Valsartan Promoting Atherosclerotic Plaque Stabilization by Upregulating Renalase: A Potential-Related Gene of Atherosclerosis.
Arg kinase-binding protein 2 (ArgBP2) interaction with α-actinin and actin stress fibers inhibits cell migration.
Wang B, Fan X, Wang L, Wei X
Molecular carcinogenesis 2024 Jun;63(6):1174-1187
Molecular carcinogenesis 2024 Jun;63(6):1174-1187
Integrative multi-omic profiling of adult mouse brain endothelial cells and potential implications in Alzheimer's disease.
Yu M, Nie Y, Yang J, Yang S, Li R, Rao V, Hu X, Fang C, Li S, Song D, Guo F, Snyder MP, Chang HY, Kuo CJ, Xu J, Chang J
Cell reports 2023 Nov 28;42(11):113392
Cell reports 2023 Nov 28;42(11):113392
SORBS2 as a molecular target for atherosclerosis in patients with familial hypercholesterolemia.
Liu MM, Peng J, Guo YL, Zhu CG, Wu NQ, Xu RX, Dong Q, Cui CJ, Li JJ
Journal of translational medicine 2022 May 19;20(1):233
Journal of translational medicine 2022 May 19;20(1):233
The interaction protein of SORBS2 in myocardial tissue to find out the pathogenic mechanism of LVNC disease.
Li C, Zheng Y, Liu Y, Jin GH, Pan H, Yin F, Wu J
Aging 2022 Jan 20;14(2):800-810
Aging 2022 Jan 20;14(2):800-810
Oncogenic AURKA-enhanced N(6)-methyladenosine modification increases DROSHA mRNA stability to transactivate STC1 in breast cancer stem-like cells.
Peng F, Xu J, Cui B, Liang Q, Zeng S, He B, Zou H, Li M, Zhao H, Meng Y, Chen J, Liu B, Lv S, Chu P, An F, Wang Z, Huang J, Zhan Y, Liao Y, Lu J, Xu L, Zhang J, Sun Z, Li Z, Wang F, Lam EW, Liu Q
Cell research 2021 Mar;31(3):345-361
Cell research 2021 Mar;31(3):345-361
Musk ketone induces apoptosis of gastric cancer cells via downregulation of sorbin and SH3 domain containing 2.
An J, Wang H, Ma X, Hu B, Yan Y, Yan Y, Su Z
Molecular medicine reports 2021 Jun;23(6)
Molecular medicine reports 2021 Jun;23(6)
Elevated myocardial SORBS2 and the underlying implications in left ventricular noncompaction cardiomyopathy.
Li C, Liu F, Liu S, Pan H, Du H, Huang J, Xie Y, Li Y, Zhao R, Wei Y
EBioMedicine 2020 Mar;53:102695
EBioMedicine 2020 Mar;53:102695
Valsartan Promoting Atherosclerotic Plaque Stabilization by Upregulating Renalase: A Potential-Related Gene of Atherosclerosis.
Zhou M, Ma C, Liu W, Liu H, Wang N, Kang Q, Li P
Journal of cardiovascular pharmacology and therapeutics 2015 Sep;20(5):509-19
Journal of cardiovascular pharmacology and therapeutics 2015 Sep;20(5):509-19
Arg kinase-binding protein 2 (ArgBP2) interaction with α-actinin and actin stress fibers inhibits cell migration.
Anekal PV, Yong J, Manser E
The Journal of biological chemistry 2015 Jan 23;290(4):2112-25
The Journal of biological chemistry 2015 Jan 23;290(4):2112-25
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Supportive validation
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- Proteintech Group (provider)
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- Experimental details
- The SORBS2 antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human SORBS2. This antibody recognizes human, mouse antigen. The SORBS2 antibody has been validated for the following applications: ELISA, IP analysis.