Antibody data
- Antibody Data
- Antigen structure
- References [12]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunohistochemistry [1]
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Validation data
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- Product number
- 12195-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#12195-1-AP, RRID:AB_2215198
- Product name
- VPS33B antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated VPS33B antibody (Cat. #12195-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references METTL16 promotes osteosarcoma progression by downregulating VPS33B in an m(6) A-dependent manner.
VPS33B interacts with NESG1 to suppress cell growth and cisplatin chemoresistance in ovarian cancer.
Eyes shut homolog (EYS) interacts with matriglycan of O-mannosyl glycans whose deficiency results in EYS mislocalization and degeneration of photoreceptors.
Circadian control of the secretory pathway maintains collagen homeostasis.
VPS33B negatively modulated by nicotine functions as a tumor suppressor in colorectal cancer.
Decreased expression of VPS33B correlates with disease progression and unfavorable prognosis in renal cell carcinoma.
Cellular interactome analysis of vaccinia virus K7 protein identifies three transport machineries as binding partners for K7.
Characterization of the Mammalian CORVET and HOPS Complexes and Their Modular Restructuring for Endosome Specificity.
Late endosomal transport and tethering are coupled processes controlled by RILP and the cholesterol sensor ORP1L.
Glomerular involvement in the arthrogryposis, renal dysfunction and cholestasis syndrome.
Mycobacterium tuberculosis protein tyrosine phosphatase (PtpA) excludes host vacuolar-H+-ATPase to inhibit phagosome acidification.
Mutations in VIPAR cause an arthrogryposis, renal dysfunction and cholestasis syndrome phenotype with defects in epithelial polarization.
Cheng J, Xu Z, Tan W, He J, Pan B, Zhang Y, Deng Y
Journal of cellular physiology 2024 Mar;239(3):e31068
Journal of cellular physiology 2024 Mar;239(3):e31068
VPS33B interacts with NESG1 to suppress cell growth and cisplatin chemoresistance in ovarian cancer.
Ning Y, Zeng Z, Deng Y, Feng W, Huang L, Liu H, Lin J, Zhang C, Fan Y, Liu L
Cancer science 2021 May;112(5):1785-1797
Cancer science 2021 May;112(5):1785-1797
Eyes shut homolog (EYS) interacts with matriglycan of O-mannosyl glycans whose deficiency results in EYS mislocalization and degeneration of photoreceptors.
Liu Y, Yu M, Shang X, Nguyen MHH, Balakrishnan S, Sager R, Hu H
Scientific reports 2020 May 8;10(1):7795
Scientific reports 2020 May 8;10(1):7795
Circadian control of the secretory pathway maintains collagen homeostasis.
Chang J, Garva R, Pickard A, Yeung CC, Mallikarjun V, Swift J, Holmes DF, Calverley B, Lu Y, Adamson A, Raymond-Hayling H, Jensen O, Shearer T, Meng QJ, Kadler KE
Nature cell biology 2020 Jan;22(1):74-86
Nature cell biology 2020 Jan;22(1):74-86
VPS33B negatively modulated by nicotine functions as a tumor suppressor in colorectal cancer.
Chen Y, Liu Z, Wang H, Tang Z, Liu Y, Liang Z, Deng X, Zhao M, Fu Q, Li L, Cai H, Xie W, Fang W
International journal of cancer 2020 Jan 15;146(2):496-509
International journal of cancer 2020 Jan 15;146(2):496-509
Decreased expression of VPS33B correlates with disease progression and unfavorable prognosis in renal cell carcinoma.
Zhang L, Xiao Y, Zhong X, Zeng Q, Hu W
International journal of clinical and experimental pathology 2019;12(3):835-842
International journal of clinical and experimental pathology 2019;12(3):835-842
Cellular interactome analysis of vaccinia virus K7 protein identifies three transport machineries as binding partners for K7.
Li Y, Zhang L, Ke Y
Virus genes 2017 Dec;53(6):814-822
Virus genes 2017 Dec;53(6):814-822
Characterization of the Mammalian CORVET and HOPS Complexes and Their Modular Restructuring for Endosome Specificity.
van der Kant R, Jonker CT, Wijdeven RH, Bakker J, Janssen L, Klumperman J, Neefjes J
The Journal of biological chemistry 2015 Dec 18;290(51):30280-90
The Journal of biological chemistry 2015 Dec 18;290(51):30280-90
Late endosomal transport and tethering are coupled processes controlled by RILP and the cholesterol sensor ORP1L.
van der Kant R, Fish A, Janssen L, Janssen H, Krom S, Ho N, Brummelkamp T, Carette J, Rocha N, Neefjes J
Journal of cell science 2013 Aug 1;126(Pt 15):3462-74
Journal of cell science 2013 Aug 1;126(Pt 15):3462-74
Glomerular involvement in the arthrogryposis, renal dysfunction and cholestasis syndrome.
Holme A, Hurcombe JA, Straatman-Iwanowska A, Inward CI, Gissen P, Coward RJ
Clinical kidney journal 2013 Apr;6(2):183-8
Clinical kidney journal 2013 Apr;6(2):183-8
Mycobacterium tuberculosis protein tyrosine phosphatase (PtpA) excludes host vacuolar-H+-ATPase to inhibit phagosome acidification.
Wong D, Bach H, Sun J, Hmama Z, Av-Gay Y
Proceedings of the National Academy of Sciences of the United States of America 2011 Nov 29;108(48):19371-6
Proceedings of the National Academy of Sciences of the United States of America 2011 Nov 29;108(48):19371-6
Mutations in VIPAR cause an arthrogryposis, renal dysfunction and cholestasis syndrome phenotype with defects in epithelial polarization.
Cullinane AR, Straatman-Iwanowska A, Zaucker A, Wakabayashi Y, Bruce CK, Luo G, Rahman F, Gürakan F, Utine E, Ozkan TB, Denecke J, Vukovic J, Di Rocco M, Mandel H, Cangul H, Matthews RP, Thomas SG, Rappoport JZ, Arias IM, Wolburg H, Knisely AS, Kelly DA, Müller F, Maher ER, Gissen P
Nature genetics 2010 Apr;42(4):303-12
Nature genetics 2010 Apr;42(4):303-12
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse testis tissue were subjected to SDS PAGE followed by western blot with 12195-1-AP(VPS33B antibody) at dilution of 1:500
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of MCF-7 cells, using VPS33B antibody 12195-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human medulloblastoma using 12195-1-AP(VPS33B antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue