26205-1-AP

antibody from Proteintech Group

Targeting: PIEZO2 C18orf30, C18orf58, FAM38B, FAM38B2, FLJ23144, FLJ23403, FLJ34907, HsT748, HsT771

ELISA (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

26205-1-AP

Provider

Proteintech Group

Product name

Piezo2 antibody

Antibody type

Polyclonal

Description

Piezo2 antibody (Cat. #26205-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IHC, ELISA.

Reactivity

Human

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

20ul, 150ul

References

Submitted references

Increased expression of the PIEZO2 mechanoreceptor in fibroblasts and endothelial cells within the lymphatic and vascular vessels of keloids.

Akita S, Ikehara S, Kiuchi M, Kokubo K, Azuma K, Ohki S, Matsuyama H, Kadarman JT, Hosokawa Y, Akimoto Y, Inaba Y, Hanaoka H, Mitsukawa N, Hirahara K, Nakayama T, Ikehara Y
The Journal of pathology 2025 Sep;267(1):105-119

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High matrix stiffness triggers testosterone decline in aging males by disrupting stem Leydig cell pool homeostasis.

Huang J, Sun L, Yin Y, Yang H, Zeng K, Huang P, Liang X, Wu J, Xiang AP, Wang J
Cell reports 2025 Sep 23;44(9):116207

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TET3 is a regulator and can be targeted for the intervention of myocardial fibrosis.

Zhu C, Hong W, Zhu Y, Xue Y, Fang Z, Jiang D, Xu Y, Kong M
EMBO molecular medicine 2025 Oct;17(10):2809-2826

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Mechanically Active Hydrogel for Healing Intestinal Fistulas through the YAP-Mediated Mechanosensitization of Intestinal Epithelial Cells.

Li Z, Li J, Chen K, Qu G, Yang S, Li S, Liu Y, Teng Y, Ma R, Huang J, Wang P, Ren J, Wu X
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Nov;12(43):e10717

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Single-cell sequencing reveals a senescent immune landscape in bone marrow lesions inducing articular cartilage damage in osteoarthritis.

Lou P, Lu X, Li M, Yao Y, Shao X, Shou D, Fan X, Tong P, Zhang Y
Bone research 2025 Nov 21;13(1):94

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Activation of mechanosensitive ion channel Piezo1 linking metabolic reprogramming and pro-inflammatory responses in hepatocellular carcinoma.

Mo J, Zhang Y, Cao C, Zheng W, Zheng L, Wang X, Wang S, Wu J, Bao Y
Cell communication and signaling : CCS 2025 Jun 13;23(1):280

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Metabolic Interplay in Acute Lung Injury: PARK7 Integrates FADS1/2-Dependent PUFA Metabolism and H3K14 Lactylation to Attenuate Endothelial Ferroptosis and Dysfunction.

Xu J, Wang Y, Mao W, Wei T, Li Y, Song J, Zhang C, Chen X, Chen C, Xu Q, Wu X, Song Y
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Dec;12(46):e08725

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Activation of mechanoreceptor Piezo1 inhibits enteric neuronal growth and migration in vitro.

Moneme C, Olutoye OO 2nd, Sobstel MF, Zhang Y, Zhou X, Kaminer JL, Hsu BA, Shen C, Mandal A, Li H, Yu L, Balaji S, Keswani SG, Cheng LS
Frontiers in molecular neuroscience 2024;17:1474025

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The Critical Role of The Piezo1/β-catenin/ATF4 Axis on The Stemness of Gli1(+) BMSCs During Simulated Microgravity-Induced Bone Loss.

Hu Y, Tian H, Chen W, Liu Y, Cao Y, Pei H, Ming C, Shan C, Chen X, Dai Z, Yang S, Shao Z, Lan S, Liu Y, Tong W
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Nov;10(32):e2303375

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Mechanosensitive channel Piezo1 is an essential regulator in cell cycle progression of optic nerve head astrocytes.

Wan Y, Wang H, Fan X, Bao J, Wu S, Liu Q, Yan X, Zhang J, Jin ZB, Xiao B, Wang N
Glia 2023 May;71(5):1233-1246

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PIEZO2 promotes cell proliferation and metastasis in colon carcinoma through the SLIT2/ROBO1/VEGFC pathway.

Shang H, Xu A, Yan H, Xu D, Zhang J, Fang X
Advances in clinical and experimental medicine : official organ Wroclaw Medical University 2023 Jul;32(7):763-776

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Mechanosensitive Piezo1 is crucial for periosteal stem cell-mediated fracture healing.

Liu Y, Tian H, Hu Y, Cao Y, Song H, Lan S, Dai Z, Chen W, Zhang Y, Shao Z, Liu Y, Tong W
International journal of biological sciences 2022;18(10):3961-3980

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Midpalatal Suture: Single-Cell RNA-Seq Reveals Intramembrane Ossification and Piezo2 Chondrogenic Mesenchymal Cell Involvement.

Gao L, Xu T, Zhang L, Li Y, Yan T, Yu G, Chen F
Cells 2022 Nov 12;11(22)