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- Antibody Data
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- References [5]
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- Validations
- Western blot [1]
- Immunohistochemistry [2]
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- Product number
- 60228-1-Ig - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#60228-1-Ig, RRID:AB_11182383
- Product name
- Cytoglobin antibody
- Antibody type
- Monoclonal
- Description
- Cytoglobin antibody (Cat. #60228-1-Ig) is a mouse monoclonal antibody that shows reactivity with human, mouse, pig, rat and has been validated for the following applications: IF, IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat, Porcine
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- 4C7E11
- Vial size
- 20ul, 150ul
Submitted references Treadmill exercise in combination with acousto-optic and olfactory stimulation improves cognitive function in APP/PS1 mice through the brain-derived neurotrophic factor- and Cygb-associated signaling pathways.
Cytoglobin augments ferroptosis through autophagic degradation of ferritin in colorectal cancer cells.
Cytoglobin attenuates melanoma malignancy but protects melanoma cells from ferroptosis.
ΔNp63α promotes Bortezomib resistance via the CYGB-ROS axis in head and neck squamous cell carcinoma.
Cytoglobin promotes sensitivity to ferroptosis by regulating p53-YAP1 axis in colon cancer cells.
Xiao B, Chu C, Lin Z, Fang T, Zhou Y, Zhang C, Shan J, Chen S, Li L
Neural regeneration research 2025 Sep 1;20(9):2706-2726
Neural regeneration research 2025 Sep 1;20(9):2706-2726
Cytoglobin augments ferroptosis through autophagic degradation of ferritin in colorectal cancer cells.
Fan C, Luo Z, Zheng Q, Xu Y, Xu Y, Chen J, Meng Y, Jiang H, Liu K, Xi Y
Molecular and cellular biochemistry 2025 May;480(5):2881-2892
Molecular and cellular biochemistry 2025 May;480(5):2881-2892
Cytoglobin attenuates melanoma malignancy but protects melanoma cells from ferroptosis.
Zou Z, Yu Q, Yang Y, Wang F, Zhu P, Zhang X, Zhang J
Molecular medicine reports 2024 Dec;30(6)
Molecular medicine reports 2024 Dec;30(6)
ΔNp63α promotes Bortezomib resistance via the CYGB-ROS axis in head and neck squamous cell carcinoma.
Zhou P, Zhang C, Song X, Zhang D, Zhu M, Zheng H
Cell death & disease 2022 Apr 9;13(4):327
Cell death & disease 2022 Apr 9;13(4):327
Cytoglobin promotes sensitivity to ferroptosis by regulating p53-YAP1 axis in colon cancer cells.
Ye S, Xu M, Zhu T, Chen J, Shi S, Jiang H, Zheng Q, Liao Q, Ding X, Xi Y
Journal of cellular and molecular medicine 2021 Apr;25(7):3300-3311
Journal of cellular and molecular medicine 2021 Apr;25(7):3300-3311
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- human heart tissue were subjected to SDS PAGE followed by western blot with 60228-1-Ig(CYGB antibody) at dilution of 1:1000
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human liver using 60228-1-Ig(CYGB antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The Cytoglobin antibody from Proteintech is a mouse monoclonal antibody to a fusion protein of human Cytoglobin. This antibody recognizes human, mouse antigen. The Cytoglobin antibody has been validated for the following applications: ELISA, WB, IHC analysis.
