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- Antibody Data
- Antigen structure
- References [4]
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- Product number
- 15651-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#15651-1-AP, RRID:AB_2247477
- Product name
- GINS3 antibody
- Antibody type
- Polyclonal
- Description
- GINS3 antibody (Cat. #15651-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IP, WB,ELISA.
- Reactivity
- Human, Mouse
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Loss of POLE3-POLE4 unleashes replicative gap accumulation upon treatment with PARP inhibitors.
Partial loss-of-function mutations in GINS4 lead to NK cell deficiency with neutropenia.
Polε Instability Drives Replication Stress, Abnormal Development, and Tumorigenesis.
Inherited GINS1 deficiency underlies growth retardation along with neutropenia and NK cell deficiency.
Hill BR, Ozgencil M, Buckley-Benbow L, Skingsley SLP, Tomlinson D, Eizmendi CO, Agnarelli A, Bellelli R
Cell reports 2024 May 28;43(5):114205
Cell reports 2024 May 28;43(5):114205
Partial loss-of-function mutations in GINS4 lead to NK cell deficiency with neutropenia.
Conte MI, Poli MC, Taglialatela A, Leuzzi G, Chinn IK, Salinas SA, Rey-Jurado E, Olivares N, Veramendi-Espinoza L, Ciccia A, Lupski JR, Aldave Becerra JC, Mace EM, Orange JS
JCI insight 2022 Nov 8;7(21)
JCI insight 2022 Nov 8;7(21)
Polε Instability Drives Replication Stress, Abnormal Development, and Tumorigenesis.
Bellelli R, Borel V, Logan C, Svendsen J, Cox DE, Nye E, Metcalfe K, O'Connell SM, Stamp G, Flynn HR, Snijders AP, Lassailly F, Jackson A, Boulton SJ
Molecular cell 2018 May 17;70(4):707-721.e7
Molecular cell 2018 May 17;70(4):707-721.e7
Inherited GINS1 deficiency underlies growth retardation along with neutropenia and NK cell deficiency.
Cottineau J, Kottemann MC, Lach FP, Kang YH, Vély F, Deenick EK, Lazarov T, Gineau L, Wang Y, Farina A, Chansel M, Lorenzo L, Piperoglou C, Ma CS, Nitschke P, Belkadi A, Itan Y, Boisson B, Jabot-Hanin F, Picard C, Bustamante J, Eidenschenk C, Boucherit S, Aladjidi N, Lacombe D, Barat P, Qasim W, Hurst JA, Pollard AJ, Uhlig HH, Fieschi C, Michon J, Bermudez VP, Abel L, de Villartay JP, Geissmann F, Tangye SG, Hurwitz J, Vivier E, Casanova JL, Smogorzewska A, Jouanguy E
The Journal of clinical investigation 2017 May 1;127(5):1991-2006
The Journal of clinical investigation 2017 May 1;127(5):1991-2006
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Supportive validation
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- Proteintech Group (provider)
- Main image
- Experimental details
- The GINS3 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human GINS3. This antibody recognizes human, mouse, rat antigen. The GINS3 antibody has been validated for the following applications: ELISA, WB analysis.
