HPA017759

antibody from Atlas Antibodies

Targeting: FBN1 FBN, MASS, MFS1, OCTD, SGS, WMS

Antibody data

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Validation data

Product number: HPA017759 - Provider product page
Provider: Atlas Antibodies
Proper citation: Atlas Antibodies Cat#HPA017759, RRID:AB_1848584
Product name: Anti-FBN1
Antibody type: Polyclonal
Reactivity: Human
Host: Rabbit
Conjugate: Unconjugated
Antigen sequence: HCVSGMGMGRGNPEPPVSGEMDDNSLSPEACYECK INGYPKRGRKRRSTNETDASNIEDQSETEANVSLA SWDVEKTAIFAFNISHVSNKVRILELLPALTTLTN HNRYLIESGNEDGFFKINQKEGISYLHFTKKKPVA GTYSLQISS
Isotype: IgG
Vial size: 100 µl
Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.

FBN1 protein structure - HPA017759 shown in red.

Enhanced validation

Submitted by: Atlas Antibodies (provider)
Enhanced method: Orthogonal validation
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Experimental details: Immunohistochemistry analysis in human placenta and liver tissues using HPA017759 antibody. Corresponding FBN1 RNA-seq data are presented for the same tissues.
Sample type: HUMAN
Orthogonal method: Orthogonal validation of protein expression using IHC by comparison to RNA-seq data of corresponding target in high and low expression tissues.

Supportive validation

Submitted by: Atlas Antibodies (provider)
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Experimental details: Immunohistochemical staining of human bronchus shows moderate cytoplasmic positivity in respiratory epithelial cells and strong positivity in collagen fibers.

Supportive validation

Submitted by: Atlas Antibodies (provider)
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Experimental details: Immunohistochemical staining of human placenta shows high expression.
Sample type: HUMAN

Supportive validation

Submitted by: Atlas Antibodies (provider)
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Experimental details: Immunohistochemical staining of human liver shows low expression as expected.
Sample type: HUMAN

Supportive validation

Submitted by: Atlas Antibodies (provider)
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Experimental details: Immunohistochemical staining of human cerebellum shows no positivity in Purkinje cells as expected.
Sample type: HUMAN

Supportive validation

Submitted by: Atlas Antibodies (provider)
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Experimental details: Immunohistochemical staining of human testis shows strong membranous positivity in peritubular myoid cells.
Sample type: HUMAN

Supportive validation

Submitted by: Atlas Antibodies (provider)
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Experimental details: Immunohistochemical staining of human placenta shows strong membranous positivity in trophoblastic cells.
Sample type: HUMAN

Supportive validation

Submitted by: Atlas Antibodies (provider)
Main image
Experimental details: Immunohistochemical staining of human liver shows no positivity in hepatocytes, as expected.
Sample type: HUMAN