Antibody data
- Antibody Data
- Antigen structure
- References [11]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunohistochemistry [1]
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Validation data
Reference
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- Product number
- 10585-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10585-1-AP, RRID:AB_2233902
- Product name
- INVS antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated INVS antibody (Cat. #10585-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Map-1a regulates Sertoli cell BTB dynamics through the cytoskeletal organization of microtubule and F-actin.
The Planar Cell Polarity Protein Fat1 in Sertoli Cell Function.
Single-molecule imaging in the primary cilium.
Inactivation of Invs/Nphp2 in renal epithelial cells drives infantile nephronophthisis like phenotypes in mouse.
Cilia proteins are biomarkers of altered flow in the vasculature.
PCP Protein Inversin Regulates Testis Function Through Changes in Cytoskeletal Organization of Actin and Microtubules.
A complement factor H homolog, heparan sulfation, and syndecan maintain inversin compartment boundaries in C. elegans cilia.
Planar cell polarity protein Dishevelled 3 (Dvl3) regulates ectoplasmic specialization (ES) dynamics in the testis through changes in cytoskeletal organization.
Cell type-specific regulation of ciliary transition zone assembly in vertebrates.
Early presentation of cystic kidneys in a family with a homozygous INVS mutation.
Afferent arteriolopathy and glomerular collapse but not segmental sclerosis induce tubular atrophy in old spontaneously hypertensive rats.
Wang L, Yan M, Bu T, Wu X, Li L, Silvestrini B, Sun F, Cheng CY, Chen H
Reproductive biology and endocrinology : RB&E 2024 Apr 3;22(1):36
Reproductive biology and endocrinology : RB&E 2024 Apr 3;22(1):36
The Planar Cell Polarity Protein Fat1 in Sertoli Cell Function.
Bu T, Wang L, Wu X, Gao S, Li X, Yun D, Yang X, Li L, Cheng CY, Sun F
Endocrinology 2024 Apr 29;165(6)
Endocrinology 2024 Apr 29;165(6)
Single-molecule imaging in the primary cilium.
Weiss LE, Love JF, Yoon J, Comerci CJ, Milenkovic L, Kanie T, Jackson PK, Stearns T, Gustavsson AK
Methods in cell biology 2023;176:59-83
Methods in cell biology 2023;176:59-83
Inactivation of Invs/Nphp2 in renal epithelial cells drives infantile nephronophthisis like phenotypes in mouse.
Li Y, Xu W, Makova S, Brueckner M, Sun Z
eLife 2023 Mar 15;12
eLife 2023 Mar 15;12
Cilia proteins are biomarkers of altered flow in the vasculature.
Gupta A, Thirugnanam K, Thamilarasan M, Mohieldin AM, Zedan HT, Prabhudesai S, Griffin MR, Spearman AD, Pan A, Palecek SP, Yalcin HC, Nauli SM, Rarick KR, Zennadi R, Ramchandran R
JCI insight 2022 Mar 22;7(6)
JCI insight 2022 Mar 22;7(6)
PCP Protein Inversin Regulates Testis Function Through Changes in Cytoskeletal Organization of Actin and Microtubules.
Li L, Gao S, Wang L, Bu T, Chu J, Lv L, Tahir A, Mao B, Li H, Li X, Wang Y, Wu X, Ge R, Cheng CY
Endocrinology 2022 Apr 1;163(4)
Endocrinology 2022 Apr 1;163(4)
A complement factor H homolog, heparan sulfation, and syndecan maintain inversin compartment boundaries in C. elegans cilia.
Acker N, Smith H, Devine C, Oltjen SL, Tsiropoulou S, Smit-McBride Z, Lange K, Blacque OE, Matsubara JA, Gordus A, Golden A, Vogel BE
Proceedings of the National Academy of Sciences of the United States of America 2021 Apr 20;118(16)
Proceedings of the National Academy of Sciences of the United States of America 2021 Apr 20;118(16)
Planar cell polarity protein Dishevelled 3 (Dvl3) regulates ectoplasmic specialization (ES) dynamics in the testis through changes in cytoskeletal organization.
Li L, Mao B, Yan M, Wu S, Ge R, Lian Q, Cheng CY
Cell death & disease 2019 Feb 26;10(3):194
Cell death & disease 2019 Feb 26;10(3):194
Cell type-specific regulation of ciliary transition zone assembly in vertebrates.
Wiegering A, Dildrop R, Kalfhues L, Spychala A, Kuschel S, Lier JM, Zobel T, Dahmen S, Leu T, Struchtrup A, Legendre F, Vesque C, Schneider-Maunoury S, Saunier S, Rüther U, Gerhardt C
The EMBO journal 2018 May 15;37(10)
The EMBO journal 2018 May 15;37(10)
Early presentation of cystic kidneys in a family with a homozygous INVS mutation.
Oud MM, van Bon BW, Bongers EM, Hoischen A, Marcelis CL, de Leeuw N, Mol SJ, Mortier G, Knoers NV, Brunner HG, Roepman R, Arts HH
American journal of medical genetics. Part A 2014 Jul;164A(7):1627-34
American journal of medical genetics. Part A 2014 Jul;164A(7):1627-34
Afferent arteriolopathy and glomerular collapse but not segmental sclerosis induce tubular atrophy in old spontaneously hypertensive rats.
Leh S, Hultström M, Rosenberger C, Iversen BM
Virchows Archiv : an international journal of pathology 2011 Jul;459(1):99-108
Virchows Archiv : an international journal of pathology 2011 Jul;459(1):99-108
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- MCF7 cells were subjected to SDS PAGE followed by western blot with 10585-1-AP(INVS antibody) at dilution of 1:100
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of Hela cells, using INVS antibody 10585-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human breast cancer using 10585-1-AP(INVS antibody) at dilution of 1:100 (under 25x lens)
- Sample type
- tissue