Explore
Validate
Learn
Western blot
ELISAAntibody data
- Antibody Data
- Antigen structure
- References [13]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
Submit
Validation data
Reference
Comment
Report error
- Product number
- 11278-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#11278-1-AP, RRID:AB_2207542
- Product name
- Tom22 antibody
- Antibody type
- Polyclonal
- Description
- Tom22 antibody (Cat. #11278-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references SENP6 Maintains Mitochondrial Homeostasis by Regulating Mitochondrial Protein Import Through deSUMOylation of TOM40.
Mitochondrial ROS triggers mitophagy through activating the DNA damage response signaling pathway.
USP14 inhibits mitophagy and promotes tumorigenesis and chemosensitivity through deubiquitinating BAG4 in microsatellite instability-high colorectal cancer.
TOMM20 as a driver of cancer aggressiveness via oxidative phosphorylation, maintenance of a reduced state, and resistance to apoptosis.
Bag3 Regulates Mitochondrial Function and the Inflammasome Through Canonical and Noncanonical Pathways in the Heart.
SARS-CoV-2 infection alters mitochondrial and cytoskeletal function in human respiratory epithelial cells mediated by expression of spike protein.
Impact prediction of translocation of the mitochondrial outer membrane 70 as biomarker in Alzheimer's disease.
UBXD8 mediates mitochondria-associated degradation to restrain apoptosis and mitophagy.
Dynamic O-GlcNAcylation coordinates ferritinophagy and mitophagy to activate ferroptosis.
HPDL deficiency causes a neuromuscular disease by impairing the mitochondrial respiration.
Mutations in TOMM70 lead to multi-OXPHOS deficiencies and cause severe anemia, lactic acidosis, and developmental delay.
Tom20 senses iron-activated ROS signaling to promote melanoma cell pyroptosis.
Mitochondrial E3 ubiquitin ligase MARCH5 controls mitochondrial fission and cell sensitivity to stress-induced apoptosis through regulation of MiD49 protein.
Hu L, Li J, Guo H, Su L, Dong P, Huang J, Liu Y, Liu X, Luo Z, Xiong W, Ju Z, Zhou Q, Wang H, Wang W
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Oct;12(40):e03408
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Oct;12(40):e03408
Mitochondrial ROS triggers mitophagy through activating the DNA damage response signaling pathway.
Guo QQ, Wang SS, Jiang XY, Xie XC, Zou Y, Liu JW, Guo Y, Li YH, Liu XY, Hao S, Zhang XY, Wu XX, Lu SM, Xu HD, Guo WD, Feng YL, Wang CG, Zhang SP, Li JB, Liu C, Song XY, Finkel T, Cao L
Proceedings of the National Academy of Sciences of the United States of America 2025 Oct 7;122(40):e2502841122
Proceedings of the National Academy of Sciences of the United States of America 2025 Oct 7;122(40):e2502841122
USP14 inhibits mitophagy and promotes tumorigenesis and chemosensitivity through deubiquitinating BAG4 in microsatellite instability-high colorectal cancer.
Wang Z, Yu C, Xie G, Tao K, Yin Z, Lv Q
Molecular medicine (Cambridge, Mass.) 2025 May 2;31(1):163
Molecular medicine (Cambridge, Mass.) 2025 May 2;31(1):163
TOMM20 as a driver of cancer aggressiveness via oxidative phosphorylation, maintenance of a reduced state, and resistance to apoptosis.
Islam R, Roche ME, Lin Z, Whitaker-Menezes D, Diaz-Barros V, Serrano E, Martinez Cantarin MP, Philp NJ, Basu Mallick A, Martinez-Outschoorn U
Molecular oncology 2025 Aug;19(8):2431-2455
Molecular oncology 2025 Aug;19(8):2431-2455
Bag3 Regulates Mitochondrial Function and the Inflammasome Through Canonical and Noncanonical Pathways in the Heart.
Wang J, Tomar D, Martin TG, Dubey S, Dubey PK, Song J, Landesberg G, McCormick MG, Myers VD, Merali S, Merali C, Lemster B, McTiernan CF, Khalili K, Madesh M, Cheung JY, Kirk JA, Feldman AM
JACC. Basic to translational science 2023 Jul;8(7):820-839
JACC. Basic to translational science 2023 Jul;8(7):820-839
SARS-CoV-2 infection alters mitochondrial and cytoskeletal function in human respiratory epithelial cells mediated by expression of spike protein.
Yeung-Luk BH, Narayanan GA, Ghosh B, Wally A, Lee E, Mokaya M, Wankhade E, Zhang R, Lee B, Park B, Resnick J, Jedlicka A, Dziedzic A, Ramanathan M, Biswal S, Pekosz A, Sidhaye VK
mBio 2023 Aug 31;14(4):e0082023
mBio 2023 Aug 31;14(4):e0082023
Impact prediction of translocation of the mitochondrial outer membrane 70 as biomarker in Alzheimer's disease.
Cao X, Chen Y, Sang X, Xu S, Xie Z, Zhu Z, Wang P, Bi J, Xu L
Frontiers in aging neuroscience 2022;14:1013943
Frontiers in aging neuroscience 2022;14:1013943
UBXD8 mediates mitochondria-associated degradation to restrain apoptosis and mitophagy.
Zheng J, Cao Y, Yang J, Jiang H
EMBO reports 2022 Oct 6;23(10):e54859
EMBO reports 2022 Oct 6;23(10):e54859
Dynamic O-GlcNAcylation coordinates ferritinophagy and mitophagy to activate ferroptosis.
Yu F, Zhang Q, Liu H, Liu J, Yang S, Luo X, Liu W, Zheng H, Liu Q, Cui Y, Chen G, Li Y, Huang X, Yan X, Zhou J, Chen Q
Cell discovery 2022 May 3;8(1):40
Cell discovery 2022 May 3;8(1):40
HPDL deficiency causes a neuromuscular disease by impairing the mitochondrial respiration.
Sun Y, Wei X, Fang F, Shen Y, Wei H, Li J, Ye X, Zhan Y, Ye X, Liu X, Yang W, Li Y, Geng X, Huang X, Ruan Y, Qin Z, Yi S, Lyu J, Fang H, Yu Y
Journal of genetics and genomics = Yi chuan xue bao 2021 Aug 20;48(8):727-736
Journal of genetics and genomics = Yi chuan xue bao 2021 Aug 20;48(8):727-736
Mutations in TOMM70 lead to multi-OXPHOS deficiencies and cause severe anemia, lactic acidosis, and developmental delay.
Wei X, Du M, Xie J, Luo T, Zhou Y, Zhang K, Li J, Chen D, Xu P, Jia M, Zhou H, Fang H, Lyu J, Yang Y
Journal of human genetics 2020 Mar;65(3):231-240
Journal of human genetics 2020 Mar;65(3):231-240
Tom20 senses iron-activated ROS signaling to promote melanoma cell pyroptosis.
Zhou B, Zhang JY, Liu XS, Chen HZ, Ai YL, Cheng K, Sun RY, Zhou D, Han J, Wu Q
Cell research 2018 Dec;28(12):1171-1185
Cell research 2018 Dec;28(12):1171-1185
Mitochondrial E3 ubiquitin ligase MARCH5 controls mitochondrial fission and cell sensitivity to stress-induced apoptosis through regulation of MiD49 protein.
Xu S, Cherok E, Das S, Li S, Roelofs BA, Ge SX, Polster BM, Boyman L, Lederer WJ, Wang C, Karbowski M
Molecular biology of the cell 2016 Jan 15;27(2):349-59
Molecular biology of the cell 2016 Jan 15;27(2):349-59
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- human liver tissue were subjected to SDS PAGE followed by western blot with 11278-1-AP(TOMM22 antibody) at dilution of 1:500
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The Tom22 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human Tom22. This antibody recognizes human antigen. The Tom22 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
