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ImmunocytochemistryAntibody data
- Antibody Data
- Antigen structure
- References [1]
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- Validations
- Immunocytochemistry [5]
- Immunohistochemistry [4]
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- Product number
- PA5-58684 - Provider product page
- Provider
- Invitrogen Antibodies
- Product name
- OTUB1 Polyclonal Antibody
- Antibody type
- Polyclonal
- Antigen
- Recombinant protein fragment
- Description
- Immunogen sequence: AAEEPQQQKQ EPLGSDSEGV NCLAYDEAIM AQQDRIQQEI AVQNPLVSER LELSVLYKEY AEDDNIYQQK IKDLHKKYSY IRKTRPD Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 100%.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100 µL
- Concentration
- 0.1 mg/mL
- Storage
- Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Submitted references OTUB1 inhibits CNS autoimmunity by preventing IFN-γ-induced hyperactivation of astrocytes.
Wang X, Mulas F, Yi W, Brunn A, Nishanth G, Just S, Waisman A, Brück W, Deckert M, Schlüter D
The EMBO journal 2019 May 15;38(10)
The EMBO journal 2019 May 15;38(10)
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Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunofluorescent staining of OTUB1 in human cell line U-2 OS shows positivity in mitochondria. Samples were probed using an OTUB1 Polyclonal Antibody (Product # PA5-58684).
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunofluorescent staining of OTUB1 in mouse olfactory bulb shows nuclear immunoreactivity in neurons. Samples were probed using an OTUB1 Polyclonal Antibody (Product # PA5-58684).
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunofluorescent staining of OTUB1 in mouse cingulate cortex shows nuclear positivity in neurons. Samples were probed using an OTUB1 Polyclonal Antibody (Product # PA5-58684).
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunofluorescent staining of OTUB1 in mouse hippocampus shows neuronal positivity. Samples were probed using an OTUB1 Polyclonal Antibody (Product # PA5-58684).
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunofluorescent staining of OTUB1 in mouse dorsal raphe nucleus shows immunoreactivity in neurons. Samples were probed using an OTUB1 Polyclonal Antibody (Product # PA5-58684).
Supportive validation
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunohistochemical analysis of OTUB1 in human tonsil using OTUB1 Polyclonal Antibody (Product # PA5-58684) shows moderate nuclear and cytoplasmic positivity in germinal and non-germinal center cells.
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunohistochemical analysis of OTUB1 in human cerebral cortex using OTUB1 Polyclonal Antibody (Product # PA5-58684) shows moderate nuclear positivity in glial cells.
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunohistochemical analysis of OTUB1 in human small intestine using OTUB1 Polyclonal Antibody (Product # PA5-58684) shows moderate nuclear positivity in glandular cells.
- Submitted by
- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Immunohistochemical analysis of OTUB1 in human testis using OTUB1 Polyclonal Antibody (Product # PA5-58684) shows moderate nuclear and cytoplasmic positivity in cells in seminiferous ducts.
