BS3936

antibody from Bioworld Technology, Inc

Targeting: SEPTIN2 DIFF6, hNedd5, KIAA0158, NEDD5, Pnutl3, SEPT2

Western blot (Data presented on provider website)

Antibody Data

Product number

BS3936

Provider

Bioworld Technology, Inc

Product name

Septin 2 (L136) polyclonal antibody

Antibody type

Polyclonal

Antigen

Synthetic peptide, corresponding to amino acids 108-157 of Human Septin 2.

Description

The transcriptional regulation of all septins is complex, resulting in alternatively spliced variants. At least three septins (Septin 1, 2 and 4) are associated with a Tau-based paired helical filament core and may contribute to the formation of neurofibrillary tangle as integral constituents of paired helical filaments. Septin 3 (G-Septin), a GTPbinding protein, is highly expressed in brain and is regulated by protein kinase G in neurons. The human SEPT4 (H5/PNUTL2/CDCrREL-2) gene encodes ARTS (for apoptosis-related protein in the TGF ÉÇ signaling pathway), which is expressed in many cells and acts to enhance cell death induced by TGF ÉÇ or, to a lesser extent, by other apoptotic agents. ARTS is localized to mitochondria and translocates to the nucleus when apoptosis occurs.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Isotype

IgG

Vial size

100ul

Concentration

1 mg/ml

Storage

Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.