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antibody from Atlas Antibodies
Targeting: SEPTIN2
DIFF6, hNedd5, KIAA0158, NEDD5, Pnutl3, SEPT2
Western blot
ImmunocytochemistryAntibody data
- Antibody Data
- Antigen structure
- References [13]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- HPA018481 - Provider product page
- Provider
- Atlas Antibodies
- Proper citation
- Atlas Antibodies Cat#HPA018481, RRID:AB_1856684
- Product name
- Anti-SEPT2
- Antibody type
- Polyclonal
- Description
- Polyclonal Antibody against Human SEPT2, Gene description: septin 2, Alternative Gene Names: DIFF6, hNedd5, KIAA0158, NEDD5, Pnutl3, Validated applications: ICC, IHC, WB, Uniprot ID: Q15019, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 µl
- Concentration
- 0.1 mg/ml
- Storage
- Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Handling
- The antibody solution should be gently mixed before use.
Submitted references Dynamic remodeling of septin structures fine-tunes myogenic differentiation
Modular antibodies reveal DNA damage-induced mono-ADP-ribosylation as a second wave of PARP1 signaling
Blebs promote cell survival by assembling oncogenic signalling hubs
Human septins organize as octamer-based filaments and mediate actin-membrane anchoring in cells
ARP-T1-associated Bazex–Dupré–Christol syndrome is an inherited basal cell cancer with ciliary defects characteristic of ciliopathies
Junctional Localization of Septin 2 Is Required for Organization of Junctional Proteins in Static Endothelial Monolayers.
Septin2 mediates podosome maturation and endothelial cell invasion associated with angiogenesis
A SEPT1-based scaffold is required for Golgi integrity and function
A homozygous genome-edited Sept2-EGFP fibroblast cell line.
Mutations in DZIP1L, which encodes a ciliary-transition-zone protein, cause autosomal recessive polycystic kidney disease
In Contrast to Chlamydia trachomatis, Waddlia chondrophila Grows in Human Cells without Inhibiting Apoptosis, Fragmenting the Golgi Apparatus, or Diverting Post-Golgi Sphingomyelin Transport
Septins Arrange F-Actin-Containing Fibers on the Chlamydia trachomatis Inclusion and Are Required for Normal Release of the Inclusion by Extrusion
Modulation of septin and molecular motor recruitment in the microtubule environment of the Taxol‐resistant human breast cancer cell line MDA‐MB‐231
Ugorets V, Mendez P, Zagrebin D, Russo G, Kerkhoff Y, Kotsaris G, Jatzlau J, Stricker S, Knaus P
iScience 2024;27(9):110630
iScience 2024;27(9):110630
Modular antibodies reveal DNA damage-induced mono-ADP-ribosylation as a second wave of PARP1 signaling
Longarini E, Dauben H, Locatelli C, Wondisford A, Smith R, Muench C, Kolvenbach A, Lynskey M, Pope A, Bonfiglio J, Jurado E, Fajka-Boja R, Colby T, Schuller M, Ahel I, Timinszky G, O’Sullivan R, Huet S, Matic I
Molecular Cell 2023;83(10):1743-1760.e11
Molecular Cell 2023;83(10):1743-1760.e11
Blebs promote cell survival by assembling oncogenic signalling hubs
Weems A, Welf E, Driscoll M, Zhou F, Mazloom-Farsibaf H, Chang B, Murali V, Gihana G, Weiss B, Chi J, Rajendran D, Dean K, Fiolka R, Danuser G
Nature 2023;615(7952):517-525
Nature 2023;615(7952):517-525
Human septins organize as octamer-based filaments and mediate actin-membrane anchoring in cells
Martins C, Taveneau C, Castro-Linares G, Baibakov M, Buzhinsky N, Eroles M, Milanović V, Omi S, Pedelacq J, Iv F, Bouillard L, Llewellyn A, Gomes M, Belhabib M, Kuzmić M, Verdier-Pinard P, Lee S, Badache A, Kumar S, Chandre C, Brasselet S, Rico F, Rossier O, Koenderink G, Wenger J, Cabantous S, Mavrakis M
Journal of Cell Biology 2023;222(3)
Journal of Cell Biology 2023;222(3)
ARP-T1-associated Bazex–Dupré–Christol syndrome is an inherited basal cell cancer with ciliary defects characteristic of ciliopathies
Park H, Papanastasi E, Blanchard G, Chiticariu E, Bachmann D, Plomann M, Morice-Picard F, Vabres P, Smahi A, Huber M, Pich C, Hohl D
Communications Biology 2021;4(1)
Communications Biology 2021;4(1)
Junctional Localization of Septin 2 Is Required for Organization of Junctional Proteins in Static Endothelial Monolayers.
Kim J, Cooper JA
Arteriosclerosis, thrombosis, and vascular biology 2021 Jan;41(1):346-359
Arteriosclerosis, thrombosis, and vascular biology 2021 Jan;41(1):346-359
Septin2 mediates podosome maturation and endothelial cell invasion associated with angiogenesis
Collins K, Kang H, Matsche J, Klomp J, Rehman J, Malik A, Karginov A
Journal of Cell Biology 2020;219(2)
Journal of Cell Biology 2020;219(2)
A SEPT1-based scaffold is required for Golgi integrity and function
Song K, Gras C, Capin G, Gimber N, Lehmann M, Mohd S, Puchkov D, Rödiger M, Wilhelmi I, Daumke O, Schmoranzer J, Schürmann A, Krauss M
Journal of Cell Science 2019;132(3)
Journal of Cell Science 2019;132(3)
A homozygous genome-edited Sept2-EGFP fibroblast cell line.
Banko M, Mucha-Kruczynska I, Weise C, Heyd F, Ewers H
Cytoskeleton (Hoboken, N.J.) 2019 Jan;76(1):73-82
Cytoskeleton (Hoboken, N.J.) 2019 Jan;76(1):73-82
Mutations in DZIP1L, which encodes a ciliary-transition-zone protein, cause autosomal recessive polycystic kidney disease
Lu H, Galeano M, Ott E, Kaeslin G, Kausalya P, Kramer C, Ortiz-Brüchle N, Hilger N, Metzis V, Hiersche M, Tay S, Tunningley R, Vij S, Courtney A, Whittle B, Wühl E, Vester U, Hartleben B, Neuber S, Frank V, Little M, Epting D, Papathanasiou P, Perkins A, Wright G, Hunziker W, Gee H, Otto E, Zerres K, Hildebrandt F, Roy S, Wicking C, Bergmann C
Nature Genetics 2017;49(7):1025-1034
Nature Genetics 2017;49(7):1025-1034
In Contrast to Chlamydia trachomatis, Waddlia chondrophila Grows in Human Cells without Inhibiting Apoptosis, Fragmenting the Golgi Apparatus, or Diverting Post-Golgi Sphingomyelin Transport
Dille S, Kleinschnitz E, Kontchou C, Nölke T, Häcker G, Morrison R
Infection and Immunity 2015;83(8):3268-3280
Infection and Immunity 2015;83(8):3268-3280
Septins Arrange F-Actin-Containing Fibers on the Chlamydia trachomatis Inclusion and Are Required for Normal Release of the Inclusion by Extrusion
Volceanov L, Herbst K, Biniossek M, Schilling O, Haller D, Nölke T, Subbarayal P, Rudel T, Zieger B, Häcker G, Cossart P
mBio 2014;5(5)
mBio 2014;5(5)
Modulation of septin and molecular motor recruitment in the microtubule environment of the Taxol‐resistant human breast cancer cell line MDA‐MB‐231
Froidevaux‐Klipfel L, Poirier F, Boursier C, Crépin R, Poüs C, Baudin B, Baillet A
PROTEOMICS 2011;11(19):3877-3886
PROTEOMICS 2011;11(19):3877-3886
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Enhanced validation
- Submitted by
- Atlas Antibodies (provider)
- Enhanced method
- Genetic validation
- Main image
- Experimental details
- Western blot analysis in U-251MG cells transfected with control siRNA, target specific siRNA probe #1 and #2, using Anti-SEPT2 antibody. Remaining relative intensity is presented. Loading control: Anti-PPIB.
- Sample type
- Human
- Protocol
- Protocol
