Antibody data
- Antibody Data
- Antigen structure
- References [7]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- 13526-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#13526-1-AP, RRID:AB_2254797
- Product name
- ZnT6 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated ZnT6 antibody (Cat. #13526-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: WB,ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Transcriptional responses of four slc30a/znt family members and their roles in Zn homeostatic modulation in yellow catfish Pelteobagrus fulvidraco.
Detailed analyses of the crucial functions of Zn transporter proteins in alkaline phosphatase activation.
Zinc transporters ZnT3 and ZnT6 are downregulated in the spinal cords of patients with sporadic amyotrophic lateral sclerosis.
Deregulation of subcellular biometal homeostasis through loss of the metal transporter, Zip7, in a childhood neurodegenerative disorder.
Deregulation of biometal homeostasis: the missing link for neuronal ceroid lipofuscinoses?
Altered biometal homeostasis is associated with CLN6 mRNA loss in mouse neuronal ceroid lipofuscinosis.
Tissue nonspecific alkaline phosphatase is activated via a two-step mechanism by zinc transport complexes in the early secretory pathway.
Song CC, Chen GH, Zhong CC, Chen F, Chen SW, Luo Z
Biochimica et biophysica acta. Gene regulatory mechanisms 2021 Aug;1864(8):194723
Biochimica et biophysica acta. Gene regulatory mechanisms 2021 Aug;1864(8):194723
Detailed analyses of the crucial functions of Zn transporter proteins in alkaline phosphatase activation.
Suzuki E, Ogawa N, Takeda TA, Nishito Y, Tanaka YK, Fujiwara T, Matsunaga M, Ueda S, Kubo N, Tsuji T, Fukunaka A, Yamazaki T, Taylor KM, Ogra Y, Kambe T
The Journal of biological chemistry 2020 Apr 24;295(17):5669-5684
The Journal of biological chemistry 2020 Apr 24;295(17):5669-5684
Zinc transporters ZnT3 and ZnT6 are downregulated in the spinal cords of patients with sporadic amyotrophic lateral sclerosis.
Kaneko M, Noguchi T, Ikegami S, Sakurai T, Kakita A, Toyoshima Y, Kambe T, Yamada M, Inden M, Hara H, Oyanagi K, Inuzuka T, Takahashi H, Hozumi I
Journal of neuroscience research 2015 Feb;93(2):370-9
Journal of neuroscience research 2015 Feb;93(2):370-9
Deregulation of subcellular biometal homeostasis through loss of the metal transporter, Zip7, in a childhood neurodegenerative disorder.
Grubman A, Lidgerwood GE, Duncan C, Bica L, Tan JL, Parker SJ, Caragounis A, Meyerowitz J, Volitakis I, Moujalled D, Liddell JR, Hickey JL, Horne M, Longmuir S, Koistinaho J, Donnelly PS, Crouch PJ, Tammen I, White AR, Kanninen KM
Acta neuropathologica communications 2014 Feb 28;2:25
Acta neuropathologica communications 2014 Feb 28;2:25
Deregulation of biometal homeostasis: the missing link for neuronal ceroid lipofuscinoses?
Grubman A, Pollari E, Duncan C, Caragounis A, Blom T, Volitakis I, Wong A, Cooper J, Crouch PJ, Koistinaho J, Jalanko A, White AR, Kanninen KM
Metallomics : integrated biometal science 2014 Apr;6(4):932-43
Metallomics : integrated biometal science 2014 Apr;6(4):932-43
Altered biometal homeostasis is associated with CLN6 mRNA loss in mouse neuronal ceroid lipofuscinosis.
Kanninen KM, Grubman A, Caragounis A, Duncan C, Parker SJ, Lidgerwood GE, Volitakis I, Ganio G, Crouch PJ, White AR
Biology open 2013 Jun 15;2(6):635-46
Biology open 2013 Jun 15;2(6):635-46
Tissue nonspecific alkaline phosphatase is activated via a two-step mechanism by zinc transport complexes in the early secretory pathway.
Fukunaka A, Kurokawa Y, Teranishi F, Sekler I, Oda K, Ackland ML, Faundez V, Hiromura M, Masuda S, Nagao M, Enomoto S, Kambe T
The Journal of biological chemistry 2011 May 6;286(18):16363-73
The Journal of biological chemistry 2011 May 6;286(18):16363-73
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Supportive validation
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- Proteintech Group (provider)
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- Experimental details
- The SLC30A6 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human SLC30A6. This antibody recognizes human, mouse, rat antigen. The SLC30A6 antibody has been validated for the following applications: ELISA, WB analysis.