Antibody data
- Antibody Data
- Antigen structure
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- Product number
- BS8795 - Provider product page
- Provider
- Bioworld Technology, Inc
- Product name
- UIMC1 polyclonal antibody
- Antibody type
- Polyclonal
- Antigen
- BRCA1-A complex subunit RAP80; Receptor-associated protein 80; Retinoid X receptor-interacting protein 110; Ubiquitin interaction motif-containing protein 1; UIMC1; RAP80, RXRIP110
- Description
- Receptor-associated protein 80 (RAP80), also known as Ubiquitin interaction motif-containing protein 1 (UIMC1) or Retinoid X receptor-interacting protein 110 (RXRIP110), is a 719 amino acid protein. Acting as a transcription repressor, RAP80 interacts with GCNF, thereby blocking GCNF interaction with the corepressor N-CoR. Localized to the nucleus, RAP80 is phosphorylated upon DNA damage. RAP80 contains two nuclear localization signals and one UIM (ubiquitin-interacting motif) repeat in the N-terminus, while the C-terminus contains two zinc fingers, a third nuclear localization signal and a potential PEST sequence. RAP80 is expressed as four isoforms produced by alternative splicing and is present in thymus, testis, heart and ovary.
- Reactivity
- Human
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100ul
- Concentration
- 1 mg/ml
- Storage
- Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
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